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Lesson Plan – Lipids (SBI4U) Curriculum Expectations: - B2.3: construct and draw three-dimensional molecular models of important biochemical compounds (lipids) B3.2: describe the structure of important biochemical compounds (lipids) and explain their function within cells B3.3: identify common functional groups within biological molecules and explain how they contribute to the function of each molecule Lesson Structure of Lipids - Elemental composition & description of basic properties Energy-rich, hydrophobic, thermoregulation, building blocks for membranes & hormones 5 types of lipids: fatty acids, fats, phospholipids, steroids, waxes Fatty Acids & Fats - Molecular model kit: construct a short fatty acid chain Make a glycerol model and ask for volunteers to link 3 fatty acids to glycerol to make a triglyceride (dehydration synthesis) Demonstrate saturated vs unsaturated fats (kink) & explain significance o Saturated: obtained from animals, solid at room temperature (butter, lard, yogurt, milk) o Unsaturated: obtained from plants, liquid/oil at room temperature Monounsaturated fats: olives, rapeseed, nuts, avocados and their oils Polyunsaturated fats: omega-6 (sunflower seeds, sesame, walnuts, corn and their oils) & omega-3 (salmon, mackerel, herring, trout, soybean, flax seed and their oils) o Ask question: which fat is healthier & why? (Answer: least to most healthiest is saturated, monounsaturated, omega-6, omega-3 (heart-healthy)) o “trans fat free” labels may not mean 0g of trans fat! It may have less than 0.5g o Applies to other nutrient facts too (e.g. calorie free means less than 5 calories per serving) Phospholipids - Draw structure & compare with fat Hydrophobic sand in water demonstration Describe significance of polarity (amphipathic molecule) in terms of cell membrane Steroids - - Similar to phospholipids (hydrophobic & hydrophilic properties) Cholesterol/phytosterol fluidity of cell membrane Cholesterol vitamin D; too much cholesterol atherosclerosis heart attack Sex hormones (estrogen, testosterone) & anabolic steroids (mimics testosterone; side effects include high blood pressure, reduced growth in youth, depression, suicidal tendencies, change in sex hormone levels) Testosterone vs estradiol molecular structure and stability Waxes - Long fatty acid chains linked to alcohols/carbon rings Serve as protection from predators for fruits and leaves (cutin) Also found on feathers of birds & furs of some animals acting as a water repellent Copy table (pg. 37 textbook)