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Vitamins/Minerals Review for Midterm #3 BIOL 103 Details on your midterm! • 50 Multiple Choice questions (100 points) • Short Answers • Topics – Chapter 9: Vitamins – Chapter 10: Water and Minerals – Chapter 11: Sports Nutrition – Documentary Movie #1 Bring with you… • • • • Scantron (Green) Pencil/Eraser 3x5 Cheat Sheet, double sided (optional) No calculator is necessary! Chapter 9: Vitamins • Fat-soluble vs. water-soluble vitamins – Which is stored in small or large amounts? – Which is absorbed into blood or lymphatic system? – Which is more vulnerable to cooking losses? Understanding Vitamins • Food preparation affects vitamin content in food – Examples: Source, Sunlight, Moisture, Growing conditions, plant’s maturity at harvest, packaging and storage. • Enrichment vs. Fortification • Provitamins: inactive forms of vitamins Categorize & Memorize • For all of your vitamins, know: 1. 2. 3. 4. 5. 6. Fat or water soluble Active form (fat-soluble) Main functions Deficiency/Toxicity Food source Interactions with other vitamins/minerals inhibition/absorption Fat-Soluble Vitamin Example #1 • Vitamin A/Retinol 1. Food source: liver, egg yolks, milk • • Animals: retinoids Plants: provitamin A carotenoids 2. Function: vision, cell development, immunity, bones, reproduction, skin 3. Deficiency: Xerophtalmia, Hyperkeratosis 4. Toxicity: Teratogen, Discoloration of skin Fat-Soluble Vitamin Example #2 • Vitamin K1/K2/menaquinones 1. 2. 3. 4. Food source: Green veggies + gut bacteria Function: Blood clotting, bone formations Deficiency: Newborn at risk Toxicity: may interfere with blood clotting meds Water-Soluble Vitamins • Many water-soluble vitamins act as coenzymes in energy metabolism of macronutrients or as antioxidants. • What to keep in mind: – – – – – Both their vitamin names/#s Function Food sources Toxicity vs. Deficiency Interactions with other vitamins/minerals inhibition/absorption Water-Soluble Vitamin Examples • Thiamin/B1 1. 2. 3. 4. Food source: pork, seafood, nuts/seeds, grain Functions: Coenzyme of TPP Deficiency: Beriberi Toxicity: None • Niacin/B3 1. 2. 3. 4. 5. Food source: tryptophan from poultry Functions: coenzyme in energy metabolism, FA synthesis Deficiency: Pellegra (4 D’s) Toxicity: Skin flushing, liver damage Interaction: need B1, B6, and iron to convert to B3 Homocysteine • High levels of homocysteine increases heart disease – B6/Pyridoxine – B9/Folate – B12/Cobalamin – Choline Anemia • Anemia can be caused by: – Low RBC count • Copper deficiency – may be macro or micro or normocytic… – Low amount of hemoglobin in each RBC. • Microcytic vs. Macrocytic Anemia – Microcytic hypochromic anemia: (small, pale) • B6 or iron deficiency – Macrocytic anemia: (enlarged, underdeveloped) • B9 deficiency – needed for DNA and RBC synthesis • B12 deficiency via pernicious anemia (damaged stomach linings) Water • When minerals or salts dissolve in water, they form ions (electrolytes) – Cations vs. Anions • Osmosis: diluted to concentrated • Functions of water • Dehydration/Intoxication Water Balance • Water intake/sources of water? • Water excretion: – Insensible water loss (1/4-1/2): lungs and skin – Urine – Illness – External factors (low humidity, salty foods, etc.) • Regulation: – Hormones (ADH, Aldosterone) – Is thirst a reliable? Understanding Minerals • Minerals – Inorganic – Not destroyed by heat, light, acidity, alkalinity – Micronutrients (needed in small amounts) – Grouped as: 1. Major minerals: Na, K, Cl, Ca, P, Mg, S 2. Trace minerals: Fe, Zn, Se, I, Cu, Mn, Fl, Cr, Mo – Involved in body structure and regulation Categorize and Memorize! • For all of your minerals, know: 1. 2. 3. 4. Main functions Deficiency/Toxicity Food source Interactions with other vitamins/minerals/phytates/oxalates inhibition/absorption Minerals Example • Calcium – Main functions: bone remodeling, muscle contraction – Food source: Dairy products, green vegetables – Interactions with other vitamins/minerals inhibition/absorption: • Enhances iron absorption • Supplemental calcium inhibit zinc absorption – Toxicity/deficiency? Blood Calcium Regulation 1. Calcitriol: increase calcium absorption in the intestine 2. Parathyroid hormone: – Activates osteoclasts to release bone calcium increase blood calcium 3. Calcitonin: reduce blood calcium Absorption vs. Inhibition • Enhances Absorption: – Vitamin C Iron – Vitamins A, C, E Selenium • Inhibition/Competition: – Copper, Iron, Zinc, (& Calcium) – Magnesium, Calcium, Manganese (& Iron) – Copper and Molybdenum – Oxalate: Calcium + Iron – Phytates: All the minerals Relationships • Need vitamins B1, B6, and iron to convert Tryptophan to B3 • Copper & Iron – Works with ceruloplasmin, a copper-dependent enzyme required for iron transport. • Copper & Zinc – Wilson’s disease (genetic disorder that increases copper absorption) • Selenium & Iodine – Goiters: Iodine deficiency can be caused by selenium deficiency Hypothyroidism Terms I have bolded on the slides! • • • • • • • Heme vs. non-heme iron Ferritin vs. Transferrin Hemoglobin vs. Myoglobin Osteoblast vs. Osteoclast Hydroxyapaptite Keshan disease Wilson’s disease