Download seasonal flank alopecia - Delaware Valley Academy of Veterinary

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Transcript
SEASONAL FLANK ALOPECIA
Edmund J. Rosser Jr., DVM, Diplomate ACVD
Professor of Dermatology
Department of Small Animal Clinical Sciences
Michigan State University
College of Veterinary Medicine
Etiology
Unknown
Change in photoperiod important
Role of pineal gland controlled hormones
Prolactin
Melatonin
Localized hair follicle hormone receptor abnormality
Sex Predisposition
Most frequently reported in spayed females
Can occur in intact males or females and neutered males
Breed Predisposition
Boxers
Airedale Terriers
Bulldogs
Giant and Miniature Schnauzers
Bouvier de Flanders
Doberman Pinschers
Scottish Terriers
German Wirehaired Pointers
Clinical Features
Bilaterally symmetrical alopecia with hyperpigmentation
Affects primarily the flank region
May extend to the lateral thorax or dorsally
Most commonly occurs in fall/early winter and resolves in late spring/early summer.
Cyclical pattern may vary
Diagnosis
History and physical exam
Rule out other endocrine skin diseases
Hypothyroidism
Cushing’s Disease
Reproductive hormone imbalances
Histopathology
Follicular atrophy, keratin plugging, comedone formation
“Witches-foot” appearance
Hypermelanosis
Treatment
None established at this time
Manipulation of photoperiod
Use of exogenous prolactin or melatonin
Melatonin – 1-6 mg/dog TID for the duration of the Alopecic cycle. Needs to be started
prior to the onset of alopecia.