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WHAT ABOUT MELATONIN?? Melatonin is a naturally occurring hormone that has been used to treat anxiety and stress in a many animal species. Anecdotal stories abound regarding its benefits and there has been a published case report regarding potential benefits for canine noise phobia. Like most supplements or “natural” remedies, there is not strong scientific evidence of efficacy. But Melatonin might be worth trying or adding to other therapies. It does appear to help reduce anxiety in some dogs. The beneficial effects of Melatonin appear to have a rapid onset. Ideally if used, it should be started 24 hours before need, but may even have benefit at the last minute. Melatonin is available over the counter in drug and health food stores. Sustained release formulations should not be used. The dose is approximately 1 mg per 15-20 lbs and it can be given 2-3 times daily. Since Melatonin is not an FDA regulated drug there is little to no quality control in the various products marketed. The quality and bioavailability of this supplement may vary widely brand to brand. The cheapest product may not be as effective as a moderate or higher priced product. One brand that has been used with some success by Veterinary Dermatology Specialists for skin problems is Nature’s Bounty. It may be a reasonable brand to start with, but caution is still advised purchasing the best quality product.