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:::Index>Profound Human World>Knowledge Acquisition>Internal Regulation> The Function of Endocrine Glands The Function of Endocrine Glands Glands of the human body, like sweat glands or tear glands, have specialized ducts to transport the substances secreted, like sweat glands expel sweat to the skin surface, and tear ducts transport tears to the eye. But hormones secreted by endocrine glands are transported through the whole body by the bloodstream, and every communication between each endocrine gland is conducted through hormonal levels in the blood. The commander of all endocrine glands is the hypophysis, located below the brain. Hormones secreted by the pituitary gland include growth hormone that affect the metabolism of saccharides, proteins and fats in the body, therefore affecting body metabolic function. For growing children, this will affect their height; any form of gigantism or dwarfism is caused also by long-term anomaly in growth hormone secretion. The hypophysis also secretes adrenocorticotropic hormone, which stimulates the epinephrine to produce epinephrine, and thyroid-stimulating hormone affects the thyroid gland; the hypophysis also secretes luteinizing hormone and follicle-stimulating hormone. These last two hormones stimulate the growth and maturation of sexual glands; during puberty, the dormant ovaries and testis begin to develop under the influence of these two hormones, which also affect the development of secondary sexual characteristics, and the production of eggs and sperms. Adrenal glands are situated above the kidneys, and secrete epinephrine, which can be considered a protective net for body emergencies. During major and severe stress situations, epinephrine is produced in large quantities, increasing blood sugar levels, heart rate and dilating blood vessels, putting the body in the best condition to face crisis, and do things that normally should be impossible. It had been reported that during a fire, a small woman was able to transport a very heavy fridge out of the house, but afterwards it took 5 grown men to return this fridge to its original place; this is all due to epinephrine. Therefore during Olympic trials, athletes have to submit to drug tests; because of the concern that somebody may use epinephrine-based drugs, causing unfairness in the competition. Thyroid glands are located at the sides of the trachea and can be divided into thyroid and parathyroid glands. They secrete thyroxine, which affects the metabolism of the whole body. For growing children, insufficient thyroxine production affects mental All rights reserved by National Taiwan Science Education Center and body development. Parathyroid hormones are very important for the balance of electrolytes like calcium and phosphorus, and therefore affect bone development. Iodine is a very important element of thyroxine: insufficient consumption of iodine lowers thyroxine in the body, and causes thyroid swelling. At present all commercialized salt contain iodine, to prevent deficiencies. Pancreatic islets are specialized tissues located in the pancreas; unlike the digestive enzymes secreted by the pancreas, hormones secreted by the pancreatic islets circulate in the bloodstream, and affect blood sugar balance in the body. There are two types of hormones: insulin lowers blood sugar levels, while glucagon raises blood sugar levels. After every meal, the body digests the food, raising blood sugar levels and stimulating insulin production. Insulin converts blood saccharides into glycogen, to be stored in the liver. Insulin’s part in blood sugar lowering is very important, because if production is insufficient or lacking, blood levels will skyrocket, causing diabetes. Glucagon’s function is just the opposite: when blood sugar levels are low, insulin production diminishes, while glucagons secretion will increase, promoting the conversion of glycogen to blood sugar, to be used by the body. Therefore, when we are hungry, we fell light-headed, experience tremor and clamminess; but after a while these condition improve, because of glucagon releases saccharides in the blood. Testis and ovaries are reproductive organs, but they are also important endocrine glands. During puberty, luteinizing hormone and follicle-stimulating hormone stimulate male testes to produce androgens, inducing the development of secondary sexual characteristics, maturity of sexual organs and sperm production; in females, the ovaries begin to produce estrogens, inducing the development of breasts, secondary sexual characteristics and menstrual cycles. Reviewed by:Zhang, Yong-Ta、Lu, Yu-Ling professor All rights reserved by National Taiwan Science Education Center