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Unit 6: DNA to RNA to Protein Essential Knowledge: 1. DNA, and in some cases RNA, is the primary source of heritable information. I.e. Polymerase Chain Reaction (PCR), Synthesis 2. Changes in genotype can result in changes in phenotype. i.e. Sickle cell, Pesticide resistance, Antibiotic resistance 3. Gene regulation results in differential gene expression, leading to cell specialization. i.e. Promoters, Terminators, and Enhancers 4. A variety of intercellular and intracellular signal transmissions mediate gene expression. i.e. Levels of cAMP regulate metabolic gene expression in bacteria, Expression of the SRY gene triggers the male sexual development pathway in animals 5. Timing and coordination of specific events are necessary for the normal development of an organism, and these events are regulated by a variety of mechanisms. 6. Interactions between external stimuli and regulated gene expression result in specialization of cells, tissues and organs. 7. Viral replication results in genetic variation, and viral infection can introduce genetic variation into the hosts. i.e. Transduction in bacteria, Transposons present in incoming DNA Reading& Notes: While reading follow along with the posted PowerPoints 1. CH 16.1 & 16.2 2. CH 17.1 - 17.5 3. CH 18.1 – 18.4 4. CH 19.1 & 19.2 Videos: All videos are from Bozeman Biology 1. DNA and RNA – Part 1 (12:29): This should be watched after reading CH 16 2. DNA and RNA – Part 2 (10:00): This should be watched after reading CH 17 3. Gene Regulation (10:06): This should be watched after reading CH 18 4. Signal Transmission and Gene Expression (8:37): This should be watched after reading CH 18 5. Viruses (8:06): This should be watched after reading CH 19 Case Study: Posted on my website; due on Monday 01/06/14 1. Viruses: This should be done after the readings and videos. Test: Given to you in class; due on Monday 01/06/14 1. Multiple Choice: I strongly recommend doing all of the above before this. 2. Essay: Please make sure this is in your own words