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Microbiology: Bacteria and Viruses 5/14/17 Paper Topics for Microbiology: Bacteria and Viruses You may want to start your paper by choosing a specific bacterium, Archean, or virus and subsequently focus to something you find particularly interesting about that organism. Alternatively, you may want to choose a current issue or problem in microbiology and focus on the problem, covering the relevant organism from that perspective. However, it is absolutely required that you discuss the pertinent biology of the organisms you are studying in your paper. Please talk to the instructors and we can provide you with more specifics on the topics listed below. Please do not feel constrained by these suggestions. Follow your own creative idea! Recent discoveries Flu vaccine shortages Bacteria with cytoskeletons/evolutionary tree Biofilm formation in disease, the environment, or industry Quorum sensing: how bacteria communicate Development in prokaryotes- spore formation, Caulobacter, Myxococcus, Streptomyces Life in extreme environments Extraterrestrial life Biodegradation of anthropogenic compounds (PCB's, dioxins pesticides, etc.) by bacteria Evolution of life Antibiotic/antiviral resistance mechanisms How to prevent antibiotic resistance Antibacterial products Symbiotic relationships between bacteria and other organisms Viable, but non-culturable organisms Anti-bacterial effects of spices Emerging infectious diseases Avian flu SARS Increase in hepatitis C Mad cow disease (BSE) Norwalk viruses and cruise ship outbreaks Bioterrorism Pathogenesis of agents of concern- anthrax, smallpox, etc. Preparedness response- vaccines, antibiotic stockpiling, drills Microbiology: Bacteria and Viruses 5/14/17 Pathogens and links to chronic disease Helicobacter pylori and ulcers Chlamydia pneumoniae and heart disease Chlamydia and infertility Crohn’s disease Guillian-Barre syndrome Pathogens and links to malignancy Human herpes virus and Kaposi sarcoma Papilloma virus and cervical cancer Human T cell leukemia virus and leukemia Epstein Barr virus and lymphoproloferative disorders Pathogenesis (many bacteria and viruses can be examined in this context) Biotechnology Novel pharmaceutical products from bacteria or Archaea from extreme environments. Gene therapy using viral vectors Level 4 labs Food irradiation Use of PCR and DNA fingerprinting for characterization of bacterial communities in soil, biofilms or host environments. Production or biodegradation of PHVB's (i.e., biodegradable plastics) by bacteria. Epidemiology Identifying and following an outbreak Tracking foodborne pathogens Molecular methods for identifying microbes Bacteria and your body Use of botulinum toxin for cosmetic purposes Acne and bacteria Normal microbiota and prevention of disease Flatulence, intestinal bacteria, and probiotics
