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What are the differences between diffusion and active transport? Explain how active transport works to move substances across cell membranes (4 points) Explain why active transport is needed in our guts State two examples of active transport Define osmosis State the two main functions of sports drinks Explain the five steps involved in breathing in Explain why larger organisms require specialised exchange surfaces, but very small organisms do not Describe and explain the structure of a villi that enables it to act as a specialised exchange surface How does inhaled and exhaled air differ? State three examples of specialised exchange surfaces in animals State two examples of specialised exchange surfaces in plants and describe what they exchange State four reasons for why plants need water Active transport requires energy carried by ATP, diffusion does not Active transport requires special carrier proteins on the cell membrane, and diffusion doesn’t Active transport moves substances from low to high concentration, diffusion is from high to low concentration 1. Chemical joins to carrier protein 2. Energy from ATP changes carrier protein shape 3. This pushes chemical through 4. Carrier protein returns to normal shape By diffusion alone, sugar will reach equilibrium / equal concentrations between gut and cells Active transport needed to force molecules against their concentration gradient Mineral uptake in root hair cells Absorption of glucose in the gut The movement of water… Through a partially-permeable membrane… From a low to high concentration of SOLUTES 1. Replace water and ions lost through sweating 2. Replace sugars that are used in respiration Intercostal muscles CONTRACT Ribs move UP and OUT Diaphragm contracts and flattens Volume in the thorax increases and the pressure decreases This causes air to flow in Large organisms have a small surface area to volume ratio Simple diffusion wouldn’t be enough to allow substances to get to all cells 1. A good blood supply to maintain a steep concentration gradient 2. A lacteal to dissolve and transport fats 3. Thin walls (one cell thick) to decrease the diffusion distance Inhaled air has 21% oxygen, exhaled air has 17% oxygen Inhaled air has 0.04% CO2, exhaled air has 4% CO2 Alveoli (lungs), Gills of fish, Villi (lungs) Roots – active transport of ions, osmosis for water Leaves – gas exchange (CO2 and O2) 1. It’s a reactant in photosynthesis 2. Cooling to maintain enzyme optimum temperature 3. Maintains turgour pressure of cells 4. Transports substances (e.g. minerals and sugars) Describe the two forces involved in ensuring water is Cohesion: water molecules attract each other pulled up through the xylem during transpiration Adhesion: water is attracted to the walls of xylem What part of the leaf allows water to leave, and how Stomata do they work? If there is lots of water, guard cells fill to become turgid – this opens the stoma and water can leave If there isn’t much water, guard cells lose water and become flaccid Describe and explain how humidity affects As humidity increases, transpiration decreases transpiration More humidity means there is more water in the air, decreasing the concentration gradient Describe and explain how wind speed affects As wind speed increases, transpiration increases, transpiration but then plateaus Higher wind speed means more water in the air is moved away, increasing the concentration gradient. Once all the water is moved away, no more increase in transpiration can occur. Describe and explain how temperature affects As temperature increases, transpiration increases transpiration Higher temperatures mean water gains energy and evaporates at a faster rate Describe and explain how light intensity affects As light intensity increases, transpiration increases, transpiration but then plateaus More light means more stomata open, increasing transpiration. However once all stomata are open, no further increase in transpiration can occur. What are the upper chambers in the heart called? Atria (singular: atrium) What is the lower chamber of the heart that pumps a) Left ventricle blood to: b) Right ventricle a) the body? b) the lungs? What is the wall that separates the left and right Septum sides of the heart called? Which blood vessel takes blood: a) Pulmonary artery a) From the heart to lungs? b) Pulmonary vein b) From lungs to heart? c) Aorta c) From heart to body? d) Vena cava d) From body to heart? What are the valves that separate atria and Atrioventricular (AV) valves ventricles called, and what is their function? - They prevent backflow of blood What are FIVE differences between arteries and - Veins have valves, arteries don’t veins? - Veins have LARGE lumens, arteries have SMALL lumens - Arteries have thick muscular walls, arteries have thin walls - Arteries have a higher pressure than veins - Arteries are have many elastic fibres, veins do not When are stents used, and how do they work? They are used to widen blocked arteries Balloon inside the stent is inflated, then burst and removed – this creates space in the artery What are artificial hearts made of and why is this Polymers and titanium important? - Very smooth to avoid friction and clots - No antigens so body can’t reject them What two ways can damaged heart valves be treated? How is blood classified? State four components of blood and describe their functions Describe where the blood transports the following components from and to: a) Carbon dioxide b) Assimilates (e.g. sugars) from digestion c) Urea Explain how red blood cells are adapted to carry out their function What compound is created when oxygen binds to the oxygen-carrying compound of red blood cells? What does xylem transport, and where? What does phloem transport, and where? What is transpiration? 1. How is carbon dioxide produced? 2. Why does it need to be removed? 3. How is it removed? 1. How is urea produced? 2. Why does it need to be removed? 3. How is it removed? Explain the negative effects of water or ion imbalance on the body Explain how the kidneys regulate water and ion concentration What happens to sugar in the blood as it passes through the kidneys? Describe two treatments for people with kidney failure Describe the risks of kidney transplants 1. Use animal valves 2. Synthetic valves can be used Both have no risk of rejection It’s a tissue (the only liquid tissue in the body) Plasma – carries proteins, CO2 and hormones Red blood cells – carries oxygen White blood cells – destroys pathogens Platelets – cell fragments that form clots a) From respiring tissues / muscles to the lungs b) From the gut to respiring tissues/muscles c) From the liver to the kidneys Biconcave shape and no nucleus – large surface area Haemoglobin to carry oxygen Oxyhaemoglobin Water and mineral ions UP the plant Dissolves sugars from SOURCE (e.g. leaves) to SINK (e.g. roots) The movement of water from the roots, through the xylem and then out of the leaves by evaporation 1. It’s a waste product of respiration 2. It dissolves to lower pH of blood, and causes asphyxiation 3. It diffuses from blood through the alveoli and leaves with air that is breathed out 1. Ammonia formed by breakdown of amino acids – it reacts with CO2 in liver to form urea 2. Ammona/urea are alkaline and increase pH 3. Urea travels in blood to kidneys, and is filtered and dissolved in water before being excreted If solute concentration in blood is too high, water moves OUT of cells causing metabolism to cease If solute concentration in blood is too low, water moves INTO cells causing them to swell and possibly burst Water and ions pass into the NEPHRON Some water and ions are selectively reabsorbed as needed. It first enters the nephron by filtration… But ALL sugar is reabsorbed back into the blood stream 1. Frequent dialysis – patient blood passes through a partially permeable membrane to extract urea, and salts are removed or added to blood as needed 2. Kidney transplants Donor kidney could be rejected – the immune system may recognise antigens as a threat and produce antibodies to destroy it Explain two methods that are used to reduce the impact or risk of kidney rejection Describe two ways our body monitors temperature Explain two ways that the body changes to cool down if temperature is too high Explain two ways that the body changes to prevent heat loss if the temperature is too low Which organ monitors and controls blood glucose concentration? Which hormone increases the amount of glucose in the blood? Which hormone decreases the amount of glucose in the blood? Explain the steps involved in decreasing glucose concentration in the blood after eating Explain the steps involved in increasing glucose concentration in the blood after fasting Describe what causes Type 1 diabetes What four things should Type 1 diabetes sufferers do as part of their treatment? State four medical risks for people with uncontrolled Type 1 diabetes State four reasons for the human population explosion 1. Tissue typing – kidneys from donors are matched with a patient’s tissue type 2. Immunosuppressant drugs to avoid damage by immune system The hypothalamus monitors blood temperature The skin monitors external temperature 1. Vasodilation – arterioles near the skin widen… … causing blood to pass nearer to skin… … leading to heat loss by radiation 2. Sweating – skin heat transfers energy to water. As it evaporates, mean energy of remaining water decreases 1. Vasoconstriction – arterioles narrow… … causing blood to flow deeper in the body… … leading to less radiation 2. Shivering – muscles contract involuntarily leading to heat produced by respiration The pancreas Glucagon Insulin 1. Pancreas detects glucose is too high 2. Insulin is released into bloodstream 3. Insulin reaches target cells in liver/muscles, causing glucose to be stored as glycogen 4. Insulin causes all cells to increase respiration 1. Pancreas detects glucose is too low 2. Glucagon is released into bloodstream 3. Glucagon reaches target cells in liver/muscles 4. Glucagon causes glycogen to be broken into glucose which enters the bloodstream Immune system recognises antigens on pancreas cells as a threat and attacks them Pancreas can’t produce enough insulin Increase complex (starchy) carbohydrates and reduce simple carbohydrates Exercise regularly Monitor blood glucose and inject insulin at mealtimes Avoid alcohol Retinal damage blindness Ulcers in feet gangrene / loss of toes Increased risk of stroke Increased risk of heart attack Improved diets food contains more nutrients and minerals Improved sanitation / hygiene lower spread of disease Medical advances (give a specific example) Lower infant mortality rate State four problems caused by unsustainable growth World food shortages in the human population Increase in pollution Unsustainable use of resources (e.g. fossil fuels) Land used for farming and building 1. Describe why fertilisers are used 1. They provide nitrates that help plants grow 2. Explain the environmental harm they cause quickly through eutrophication 2. Nitrates leach into water sources causing water plants / algae to grow. This reduces oxygen so animals die and rot, producing CO2. Explain how burning fossil fuels leads to acid rain Sulfur dioxide dissolves in rainwater to make sulphuric acid Nitrogen dioxide dissolve to make nitric acid Carobn dioxide dissolves to make carbonic acid Explain how acid rain causes environmental harm Damages plant leaves Acidifies lakes Changes mineral availability in soil Causes bronchitis Explain two problems associated with allowing Bacteria (e.g. cholera and typhoid) may be untreated sewage into waterways present causing illness Sewage contains nitrates causing eutrophication Explain how toxic chemicals lead to bioaccumulation Toxins leach into waterways These build up in higher quantities in the food chain, as animals at higher trophic levels consume many organisms Explain the causes and effects of global dimming Incomplete combustion releases smoke / particulates into the atmosphere These can block the Sun’s rays, causing dimming Lower light intensity means less photosynthesis occurs. Describe how methane is produced agriculturally Methane produced by rearing cattle and growing and how it causes environmental problems rice crops. Methane is a powerful greenhouse gas that traps and re-emits infra-red light. This leads to global warming, causing climate change. Explain how CFCs affect the environment CFCs break down the ozone layer. This layer normally absorbs ultraviolet light. If the ozone layer is depleted, this means the rates of skin cancer increase Explain how detergents affect waterways Detergents kill microbes. This means microbes cannot rot dead plants and animals, affecting the food chain. Describe three ways that deforestation leads to an Slashing and burning trees produces CO2 by increase in CO2 combustion Left-over tree stumps rot, decomposers produce CO2 Fewer trees mean less photosynthesis so less CO2 absorbed Explain what peat is, and how it leads to CO2 Peat is made of preserved sphagnum moss. production If used as compost, it decomposes to produce CO2 Explain four biological effects of global warming Explain how carbon dioxide can be sequestered in oceans Explain three ways that humans have ensured our farming food chains are efficient Describe and explain two methods of preventing overfishing Which fungus is used to make protein-rich food, and by which process? State three common examples of biofuels State three advantages of using biofuels State and describe the disadvantage of using biofuels How is biogas made? State three uses of biogas State the difference in production between biogas and bioethanol Reduced biodiversity – therefore more extinctions as habitats destroyed Ice caps melting – leads to sea levels rising Climate change – leads to storms, droughts that affect organisms Migration patterns affected – animals winter in different countries 1. Carbon dioxide dissolves in water to form carbonic acid 2. Phytoplankton absorb CO2 through photosynthesis The number of stages (trophic levels) are reduced, meaning less energy is lost Animals are kept warm, reducing homeostasis energy loss Battery farmed animals can’t move much, reducing energy loss from respiration Large net sizes – prevents small fish being caught, so they can breed and restock oceans Fishing quotas – limiting how many, or which types, of fish allows them to restock Fusarium, used in fermentation Wood, biogas, bioethanol (alcohol) Reduced fossil fuel consumption No net increase in CO2 No particulates are produced Habitat loss due to large areas of land used for crops This leads to extinction of species Fermentation of carbohydrates from plant material and sewage… by bacteria… at a temperature between 32-35OC to produce methane and other gases Vehicle fuel Generating electricity Central heating systems Biogas requires bacteria for fermentation, bioethanol requires yeast What is bioethanol called when it is mixed with Gasohol petrol? Explain why Brazil uses gasohol (bioethanol and fuel) They don’t have natural oil reserves in their cars They have plenty of sugar cane They have plenty of land Therefore they can grow and ferment sugar cane to produce bioethanol