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Bone Formation Facial Bones Skeletal System Skull Bone Disorders Osteology – The Science of Bones Bone is living tissue it grows and changes throughout your life. You completely replace your entire skeleton about every ten years. Bone are composed of: Cells, Fibers and a Matrix ( Ca2+) The Matrix of the Bone is referred to as an Hydroxyapatite The Chemical Composition of the bone matrix is (Ca2+)10(PO4)6 (OH)2 return Structure of a Long Bone Figure 07.01 Return Bone Formation Two Types 1. Intramembranous – Develops in the connective tissue membranes in the embryo called Mesenchyma – embryonic CT 2. Endochrondral Bone Formation – Bone forms in cartilage A cartilage model of the skeleton is in place and the cartilage is removed and bone is laid down. NOTE : Bone is NOT calcified cartilage Return Return Formation of bone is called Ossification - it starts in the embryo and continues to age 18 in females and 20 in males. Within the cartilage skeleton model of the embryo are ossification centers. This is where the cartilage is being destroyed and the bone is being made. Ossification takes place in the middle of the bone shaft first and then at the ends. The bone develops moving very slowly toward the ends of the bone. Return Return Return Two types of bone are produced : Spongy Bone – Contains a lot of cavities this structure reduces weight and increases strength of the bone. This is the region that is effected by osteoporosis the most. Hemopoietic tissue (makes blood) fills the cavities of spongy bone. Compact Bone - Dense strong bone that makes up the outer surface of the bone. Compact bone is composed of millions of subunits called: Haversian Systems or Osteons Return Figure 07.02 Return Diaphysis Volksman Canal Epiphyseal Plate or Growth Plate Articular Cartilage Spongy Bone with Hemopoietic Tissue Epiphysis Return Three types of Bone Cells 1. Osteoblasts – Makes new bone 2. Osteocytes – Maintain existing bone if damage occurs. Live inside calcified bone in lacuna (“little pond” in Latin) 3. Osteoclasts – Remove bone, act like white blood cells. They are triggered by parathormone from the thyroid to breakdown bone to increase calcium level in blood. Their action can lead to osteoporosis – Loss of bone mass due to lack of calcium. Bones can become weak and brittle. Return Haversian System Lamella of bone or Osteon Canaliculi Haversian Canal Osteocyte Haversian Canal Systems Return Return Function of Bones 1. Support 2. Motion – Muscle Attachment 3. Protection – Skull protects Brain Ribs & Sternum protects Heart & Lungs 4. Calcium Storage – There is a constant exchange between bones and blood. 5. Bone Marrow – Process called Hemopoisis is the making of Red and White blood cells. In the infant red marrow is found in most of the bones. In the adult it is only found in 1. Sternum and Ribs 2. Hip Bones (iliac Crest) Take marrow samples here 3. Bodies of Vertebrae 4. Proximal end of Long Bones return Classification of Bones 1. Long Bones Upper Extremities - Humerus Radius & Ulna Lateral Medial Palm - Metacarpals Fingers - Phalanges Lower Extremities - Femur Tibia & Fibula Medial Lateral Foot - Metatarsals and Phalanges return 2. Short Bones - Wrist - Carpal bones or carpus Ankle - Tarsals bones or Tarsus 3. Irregular Bones - Vertebrae & Skull may be movable or immovable contain many irregular bones 4. Flat Bones - Scapula – Shoulder blade Clavicle – Collar bone Skull - Frontal & Parietal bones of skull 5. Sesamoid Bones “seed” – small, nodular found within tendon ex: patella (knee cap) return Identifying Characteristics of Bones 1. Fossa – Depression in a bone ex: TMJ (Temporal Mandibular Joint) forms a fossa 2. Sinus – Cavity in a bone ex: maxillary sinus – cavity above upper jaw 3. Foramen – Hole in a bone ex: Foramen Magnum – hole for spinal cord in skull 4. Meatus – Tubular structure in bone ex: External auditory meatus let sound enter skull 5. Condyles – Large smooth curved surfaces that touches another bone. ex: Distal end of femur 6. Trochanter – A large projection on a bone for muscle attachment Lec 1 return Table 07.02 Axial Skeleton Figure 07.09 Appendicular Skeleton Return Skeleton Axial Skeleton - Skull Ossicles (ear bones) Hyoid Sternum & Ribs Vertebral column Appendicular Skeleton - Upper Extremities Pectoral Girdle - clavicle & scapula (attachment to axial skeleton) Lower Extremities Pelvic Girdle – ilium, ischium, pubic bone Return Skull Two major components – 1. Skull Cap - Calvarium or cranium contains 8 bones that enclose the brain. 2. Facial Bones – 14 bones that support muscles of the face. Bones of the Calvarium – 1. Frontal – forehead – Anterior fossa of base of skull 2. Parietal – 2 – means “walls”- top of skull 1 3. Temporal – 2 – sides of skull 2 4. Occipital – posterior part of skull 6 5. Sphenoid 5 3 6. Ethmoid 4 Return Temporal Bone - Four Parts 1. Squamous – Flat/thin part of skull ( Don’t get hit here) 2. Mastoid Process – “breast” – contain sinus for middle ear. 3. Zygomatic Process – “bar” – posterior portion of cheek bone 4. Petrous portion – “hard” – houses the inner ear Occipital Bone – Thick Bone Contains the Foramen Magnum “Big Hole” Articulates with first cervical vertebra - Atlas Greek god Atlas Return Sphenoid – Floor of skull – called the keystone of the skull keeps the other bones in place. Holds the Pituitary Gland in the “Turkish Saddle” formed by the four Clinoid processes. Sphenoid Ethmoid Ethmoid Bone – “sieve” contains holes for olfactory nerves to pass through. This is called the Cribriform Plate. Return Looking down into skull Pituitary would be here Clinoid Processes “Turkish Saddle” Squamous Petrous portion V shape of Occipital is called a Lambdoidal Shape Return The immovable joints between the bones of the skull are called Sutures Anterior Posterior Return Infant Skull – Contains areas of connective tissue called Fontanelles Allows the skull to move during birth and accommodates rapid growth of brain. Return 3 Facial Bones 4 2 5 7 1 There are two of each of the facial bones 1. Maxilla – Upper Jaw called keystone of face all facial bone touch the maxilla except mandible. 2. Zygomatic Process – Anterior roof of mouth formed by maxilla 3. Nasal Bones – Forms bridge of nose 4. Lacrimal Bones – Inferior medial orbit 5. Zygomatic Bones – Middle of cheek 6. Palatine Bones – Posterior portion of the roof of the mouth 7. Vomer – Bone of lower septum of nasal cavity Return Return The Cheek is made up of : Zygomatic Process - Maxilla Zygomatic Bone Zygomatic Process - Temporal The roof of the mouth is called the Hard Palate It is composed of the: Maxilla - Anterior Palatine - Posterior Return Nose – Lateral Nose - Two inferior Conchae in the Inferior lateral nasal cavity Medial Nose - Vomer – medial nasal cavity (called the Septum) Mandible – Jaw bone only moveable joint of skull Coronoid Process Condyloid Process Part of TM Joint Ramus “branch” Angle Body Return Figure 07.12 Return Teeth—Humans have a heterodont dentition ( Different Teeth) C1 Figure 07.17 C7 T1 Ribs attach to all the Thoracic Vertebrae T12 L1 L5 C1 – Atlas C2 – Axis Odontoid Process “tooth” connects these two together allows you to rotate your head Laminectomy – Cut through this part of the vertebra to get to the spinal cord Longest spinous processes in Thoracic region Figure 07.18 Muscle attachment Spinal cord found here Rib attachment Thoracic is area most common for tumors Largest bodies in Lumbar region due to carrying all of the body’s weight Vertebral Column – Posterior Lateral Anterior Cervical Scoliosis Thoracic Lumbar Sacral Abnormal Curves – Coccyx Kyphosis – Hunchback – Accentuated Thoracic Curve Lordosis – Swayback – Accentuated Lumbar Curve Scoliosis – Lateral curve in Thoracic region more common in females begins during puberty. Intervertebral Discs – Rings of Fibrocartilage between the vertebrae Annulus Fibrosis Stiff cartilage ring Nucleus Pulposus – Soft gelatinous center Slipped Disc When someone has a slipped disc the disc doesn’t really move. The Annulus tears and the soft gelatinous center gets squeezed out. Sort of like putting pressure on a jelly donut the jelly squeezes out. Best cure is bed rest and to let the ring heal and the center to regenerate. Figure 07.21 Return Deltoid Tuberosity Surgical Neck Humerus – Bone of Arm Proximal Figure 07.25 Semilunar notch Lateral Distal Medial Figure 07.29 Female Male Common fracture site Figure 07.30 For muscle attachment, you can see how active person is by looking at this area of a bone. Patella in tendon found here Femur Articulates with femur Articulates with Talus Figure 07.31 Bumps on side of ankle Figure 07.33 Dancer’s Fracture Return Bone Fractures Box Figure 07.01a Repair of Bone Fracture 1. Severe Bleeding 2. Blood clot forms in the bone 3. Cells from the Periosteum produce Osteoblasts that produce new bone. 4. New bone fragment + Blood clot form a Callus 5. Bone forms between fracture ends called a Bony Collar 6. Osteoclasts remove excess bone Box Figure 07.01b Arthrology – Science of Joints 1. Fibrous Joints – Contain very little connective tissue between the bones. ex: sutures of the skull 2. Cartilaginous Joints – Fibrocartilage between bones – strong joints ex: Intervertebral Discs, Pubic Symphysis 3. Synovial Joints – Connections between bones of appendicular skeleton “ with egg white” ex: Humerous & Glenoid fossa, Femur & Acetabulum Synovial Fluid is there to reduce friction in the joint and to moisten and nourish the cartilage. Cartilage doesn’t have blood vessels so the cartilage celled get nourish by synovial fluid. A Bursa is a bag of synovial fluid attached to a joint that is there to reduce friction. Inflammation of the bursa is called Bursitis. Return Figure 07.35 Made of Hyaline Cartilage Produces Synovial Fluid Figure 07.37 Types of Joints Movement of a Joint Flexion - Decrease an angle Extension - Increase an angle Adduction - Bring limb toward the midline Abduction - Move limb away from midline Circumduction - Circular motion Dorsiflexion – Lift foot toward shin Supination / Pronation- rotate hand palm up or palm down Arthritis Rheumatoid Arthritis – “discharge” of synovial fluid. Disorder of the immune system, joints swell with stiffness and pain due to excess of synovial. Osteoarthritis – Breakdown of articular cartilage so bone grind on bone with pain and reduced movement Bone Loss Osteoporosis - Loss of bone mass more frequent in women. Return Plate 10 Table 07.01