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Heart Damage [ Some cancer treatments can damage the heart in different locations and in a variety of ways. In some cases, the heart’s valves may become stiff or leaky, reducing blood flow. The heart’s electrical system may become damaged, causing irregular heartbeats or arrhythmias. Some treatments can affect the pericardium, the thin sac of tissue that surrounds the heart, causing it to become inflamed or scarred. ILLUSTRATION BY ERIN MOORE ORIGINALLY PUBLISHED IN “HAZARDOUS TO YOUR HEART,” CURE SPRING 2007 ©CURE Media Group For patient handouts only ] Blocked or scarred blood vessels may prevent delivery of oxygen and nutrients to the heart and other tissues. The muscle cells of the heart, called myocytes, can become damaged and reduce the heart’s ability to contract and relax, leading to cardiomyopathy or left ventricular dysfunction. SIDE EFFECTS 81