Download Viral capsid proteins bind to receptors on host cell membrane (outer

Viral capsid proteins
bind to receptors on
host cell membrane
(outer part of host
cell)
Host cell continues to
read its own DNA, but
also starts reading
the viral DNA and
starts to make viral
proteins
Now, only viral
proteins are made, and
thousands of virus
particles are created
using the host cell’s
body
L
E
C
Genetic material (DNA)
from virus enters cell
Viral proteins destroy
the cellular DNA by
chopping it up into
little pieces
(basically, virus chops
up the brain of the
cell and turns it into
mush)
Infected cell bursts
and virus particles are
then free to infect
other cells
R
K
Host cell DNA is gone
so only viral DNA is
left. The host cell
basically got a brain
transplant and its
body is being
controlled by the evil
virus’ mind (DNA). O
Host cell can tell the
difference between its
own DNA and viral
DNA
I
Host cell is unable to
tell the difference
between its own DNA
and viral DNA
F
S
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Viral DNA
incorporates into
host cell DNA and
hides, undetected
(hibernates)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
Factors activate
viral DNA to start
making viral
proteins (wakes-up)
1. Print and laminate the first page in one color. Print this second page in a different color. To make a full set, cut all from page 1 and 1 of each from page 2. Have groups
of 2 sequence page one only, the lytic cycle. Have them put the different colored cards aside.
2. Once each group has completed the lytic cycle, check and tell them the difference between lytic and lysogenic (Lysogenic embeds itself in Host DNA and can stay there
latently for a while, like HIV can. Lysogenic is “silent but deadly”). Have them incorporate into the sequence wherever they think the two remaining cards should go (right
after “genetic material (DNA) from virus enters cell”.
 First page sequences from first box on left, down, then to next column down, then final column. (Lower left corner will spell “LIFE ROCKS”)
 Last box on page 1 “Host cell can tell the difference between its own DNA and viral DNA” is not true. To up the level of thinking you can tell your students there is
one card that isn’t true and see if they can figure it out. Or, you can simply exclude this card from your set.