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Transcript
Ocular Anatomy...where ocular disease occurs! Michael Bacigalupi, OD, MS, FAAO Texas Optometric Association Convention – 2010 Tear Film Lipid layer- secreted by the Meibomian glands of upper and lower lids. Prevents evaporation and lubricates. Aqueous layer-secreted by the Lacrimal glands. 90% of tear thickness and contains antibacterial properties. Mucus layer-secreted by goblet cells in the conjunctiva. Helps tears stick to cornea. Tear Film Layers Tear Film Clinical Notes Dry Eyes Can Be Caused by a Lack of Tear Production or an Imbalance in the Three Layers of the Tear Film Treat by either adding moisture (Artificial Tears) Preventing loss of moisture (Punctal Plugs) Controlling inflammation (Restasis or Steroids) Cornea Most powerful refracting lens Avascular tissue O.5mm thick centrally and 1.00mm thick peripherally Composed of 5 distinct layers Layers of the Cornea Epithelium-stratified squamous cells Bowman’s membrane-acellular layer Stroma-collagen fibrils make up 90% of corneal thickness Descemet’s membrane-basement membrane Endothelium-single layer of pump cells Cornea Clinical Notes Keratometry Measures the Front Curvature of the Cornea Corneal Topography Shows the Elevation of the Cornea Pachymetry Ultrasonically Measures the Thickness of the Cornea. Aqueous Humor Volume = 0.6ml Replaced every 100+ minutes Produced by the the ciliary body Similar to plasma Must maintain perfect clarity Aqueous Clinical Notes Slit Lamp Can Reveal the Presence of Cells or Protein in the Aqueous As Is Found in Uveitis or Iritis Aqueous Production Maintains Fluid Pressure Balance Within the Eye Limbus Transitional zone between the cornea and the sclera Corneal stromal lamellae are less regular and more opaque Goes from vascular to avascular Limbus Clinical Notes Location Involved in Many Ocular Disease Such As: Phlyctenulosis, Vernal Catarrh, or Trachoma. Conjunctiva Thin, translucent mucous membrane Covers the sclera and the underside of the eyelids Contains goblet cells Stratified epithelium in 3-7 layers Conjunctiva Clinical Notes Pingueculum Pterygium All Types of Conjunctivitis (Pink Eyes) GPC Sclera Hard, white shell of the eye Irregularly arranged collagen fibrils 0.3mm thick anteriorly and 1.0mm thick posterior Optic nerve penetrates through sclera at the posterior foramen Sclera Clinical Notes Episcleritis Is a Common Inflammation of the Sclera Scleritis Is a Deep Painful Inflammation of the Sclera Usually Associated With a Systemic Disease Iris Contractile diaphragm Central aperture is the pupil Heavily pigmented in brown eyes and less pigmented in green to blue eyes Iris Clinical Notes The Iris Can Become Inflamed or Torn From Trauma Neovascularization of the Iris From Advanced Diabetes Can Lead to Glaucoma Angle of the Eye Responsible for aqueous fluid balance Ciliary Body- produces aqueous Trabecular Meshwork-drains aqueous Zonules-suspends the crystalline lens Iris root Angle Clinical Notes Critical in Glaucoma Location of Laser Treatment in Laser Trabeculoplasty Can Become Clogged With Pigment or Neovascularization Leading to IOP Spikes. Crystalline Lens Transparent biconvex lens Suspended in place by the zonules Location of cataracts Composed of multiple layers like an onion Crystalline Lens Clinical Notes Cataracts Are One of the Most Common Eye Diseases Nuclear Cataracts Cloud the Center of the Lens and are Age Related Cortical Posterior Subcapsular Cataracts Can Be Caused by Age, Trauma, or Steroid Usage. Three Most Common Cataracts Cataracts What does the patient see? Vitreous Humor Fills the largest chamber of the eye 4.5ml of volume Transparent gel composed of a random network of thin Collagen fibers Attaches to the optic nerve head and the peripheral retina Vitreous Humor Clinical Notes Aging Causes the Vitreous to Degenerate and Liquefy This Can Lead to a Posterior Vitreous Detachment with Symptoms of Floaters and Flashes of Light PVD’s Increase the Risk of Retinal Detachment by 15-20%. Retina Internal lining of the eye The “film of the camera” Contains photoreceptors – rods and cones 2 basic layers – neural retina and RPE Retinal Layers Retina Clinical Notes Retinal Detachment Is an Emergency That Needs Treatment to Restore the Blood Supply As Quickly As Possible Macula The central 3 disc diameters of the retina Tightly packed with cones provides sharpest visual acuity Age Related Macular Degeneration ARMD Dry form: atrophy and aging with drusen and RPE damage Wet form: bleeding from neovascular membrane with exudates and drusen Optic Nerve Formed by the axons of 1.2 million ganglion cells Contains the central retinal artery and vein Central cupping is present at the optic nerve head Travels back through the orbit, through the posterior foramen,crosses at the optic chiasm, travels back to the occipital lobe Optic Nerve Head Optic Nerve Clinical Notes Glaucoma shows increased cupping of the ONH Papilledema is swelling of the ONH and can be caused by increase intracranial pressure Pallor indicates poor circulation to the ON OHN appears smaller in hyperopes and larger in myopes Optic Nerve Pathway Intraocular Intraorbital Intracanalicular Chiasm Intracranial MRI Optic Pathway Ocular Anatomy Review Thank You for Your Attention! Michael Bacigalupi,OD, MS, FAAO [email protected]