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Transcript
Transport of materials across the
cell membrane
Packet 5 part 2
What is a concentration gradient?
An increase or decrease in the
density of a type of molecule in a
given area.
Which way will the molecules move?
Molecules naturally spread out with their
kinetic energy.
Molecules move from high to low
concentration naturally
• Diffusion
Molecules move down their concentration gradients.
Osmosis
• Water is very important, so we talk about
water separately
• Osmosis
– diffusion of water from HIGH concentration of
water to LOW concentration of water
• across a semi-permeable membrane
Passive Transport: Simple Diffusion
• Move from HIGH to LOW concentration
• No energy required
fat
inside cell
LOW
fat
fat
fat
fat
fat
Which way
will fat move?
HIGH
outside cell
fat
fat
fat
fat
fat
fat
fat
fat
Crossing the cell membrane
• What molecules can get through the cell membrane
directly with simple diffusion?
– Small lipids (fatty acids, glycerol) can pass directly through
– small uncharged molecules like O2, CO2 and H2O (**) can also pass
directly through
Fatty
CO2 acid
O2
inside cell
salt
waste
outside cell
sugar
aa
H 2O
but…
what about
other stuff?
Protein channels
• Proteins act as doors in the membrane
– channels to allow specific molecules through
cell membrane
Facilitated Diffusion
• Move from HIGH to LOW through a protein
channel
inside cell
sugar sugar
sugar
sugar
sugar
sugar
LOW
Which way will
sugar move?
HIGH
outside cell
sugar
sugar sugar
sugar
sugar
sugar
sugar
Diffusion Summary
• Move from HIGH to LOW concentration
– directly through membrane
• simple diffusion
• no energy needed
– help through a protein channel
• facilitated diffusion (with help)
• no energy needed
HIGH
LOW
Active transport
• Cells may need molecules to move
against concentration gradient
– need to pump “uphill”
• from LOW to HIGH using energy
– protein pump (transport protein)
– requires energy
• ATP
ATP
Figure 8.19 The three types of endocytosis in animal cells
RME
Transport summary
simple
diffusion
facilitated
diffusion
No energy needed
High to low
concentration
With the concentration gradient:
Floating downstream
active
transport
energy needed
ATP
Low to high
concentration
Against the concentration gradient:
swimming against the current
Tonicity
2006-200
Keeping water balance
• Cell survival depends on balancing water uptake & water loss
• Tonicity= the relative amount of dissolved solutes in an aqueous
solution
freshwater
balanced
saltwater
Keeping water balance
•
•
•
A hypotonic solution has a concentration of solutes that is lower than
inside the cell.
A hypertonic solution has a concentration of solutes that is higher than
inside the cell.
An isotonic solution has a concentration of solutes that is equal to the
concentration inside the cell.
Solutions and osmosis
Remember, water will diffuse from an area of high
concentration to an area of low concentration.
Hypotonic Hypertonic
Less solute,
more water
The net
movement is from
the left side to the
right side.
More solute,
less water
Isotonic
The net
movement is
now equal.