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Transcript
Peter P. Domitrovich, Jr., Ph.D.
Resume:
April 23, 2017
2807 NW 25TH ST. Lawton, OK 73505 U.S.A.
Home: (580)-581-1815; Cell: (580)-514-9795;
Skype Name: live:ingridpeter_4
Email: [email protected]
Web page: http://ppdomitrovich.ingridpeter.fastmail.us/ppdomitrovich/
Skills Matrix in detail:
http://ppdomitrovich.ingridpeter.fastmail.us/ppdomitrovich/skillsmatrixdetailed.html
Skill
Cumulative FTE*
Experience
When**
Unix
> 17 years @
40hrs/wk
1986-1994; 19962008; 2008-2017
2 years @
40hrs/wk
3 months @
40hrs/wk
3 years @
40hrs/wk
2000-2013;
03/2013-07/2017
Recently, RHEL
2000-2008; 20152017
Ran HRV code
often in Cygwin
Always up-to-date
with windows OS’s
Unix system
administration
1 year @ 40hrs/wk
2000-2008
Solaris 6, 7, 8
C
6.6 years @
40hrs/wk
1991; 1996-2008;
2008-2017
Unix/C console
applications
development
C++
3 years @
40hrs/wk
2000-03/2013;
03/2013-08/2017
Apps
FORTRAN
5 years @
40hrs/wk
1986-1994; 2008f90, and f95. 19862009
MS Visual Studio
MFC/C++
10 months @
40hrs/wk
2000-2008
Java/Java Swing
3 months @
40hrs/wk
2008; 2012-2017
Linux
Cygwin
MS Windows
3 months @
40hrs/wk
1.3 years @
Bash; Ksh; Sh; Csh
40hrs/wk
DOS/DOS
1.4 months @
COMMAND SHELL
40hrs/wk
Windows/C;
2 months @
WIN32
40hrs/wk
MS Office
1 year @ 40hrs/wk
MATLAB
1996-2017
Additional
Information
Mostly Solaris
user; 1986-1991:
grad school
Mostly f77, some
2005-2008
2000-2017
1996-2008
1999
2004-2017
1991: grad school
Windows GUI
development
Java learning;
maintaining Java
Swing code
Automation or GUI
Sys admin and
automation
Win admin and
older programs
Windows GUI
Development
Since 2000
GTK 2.0
gnuplot
2 months @
40hrs/wk
1 month @
40hrs/wk
2014
Linux GUI
development
1996-2014
Used often for HRV
time series
analyses
2.4 years @
40hrs/wk
1996-2008
mathematics
2.6 years @
40hrs/wk
1996-2008; 2009,
2013-2017
* FTE =
Full-Time
Equivalent
or 40
hours per
week.
Heart Rate
Variability; some
signal processing.
Mostly HRV math
and signal
processing
**part-time
usually
MTA 98-367 Security Certificate 07/19/2016
Professional Experience:
08/14-Present
 Independent contractor tutoring in math, physics, and programming (11/14-present)
 Adjunct instructor of physics for CTC since 10/16 (no classes to teach yet).
 Established a business: retail book seller and independent tutor. (6/16-present)
 Adjunct instructor in math or physics at Cameron U, Lawton, OK (1/15-6/16)
 Adjunct instructor of physics at WOSC, Altus, OK (1/16-6/16)
 Freelance programming for Guru.com. 8/16-present.
03/13-07/14
Models and Simulations Programmer
Fires Battle Lab, 2421 NW Austin Road, Suite 214, Fort Sill, Oklahoma 73503 through Alatec
Inc., 650C Pratt Ave NW, Huntsville, AL 35801.
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Using C++ in a RHEL 5.8 64-bit OS, programmed in the modeling and simulations group. Added
new behavior to a UAV model with three degrees of freedom.
Wrote (Graphical User Interface) GUI code using GTK+2.0 with C++ in a Linux OS for a new
FIRESIM XXI GUI. Utilized g++, SCRUM, DIS, and HLA.
Performed unit and system testing. Debugged code using ddd. Merged code forward. Created
reports.
05/08-02/13
CGI/CGIFEDERAL, 1224 SW Rex Madeira Rd, Lawton, OK 73501.
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Software Engineer, Jr.
Maintained the Computer Meteorological Data-Profiler (CMDP). Helped to correct code
written in Java Swing. Tested a new capability of the CMDP using AFATDS.
Tested the Meteorological Measuring Set Profiler (MMSP) to determine its range as a function
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of latitude. Discovered inconsistencies in the measurements. Determined that there was a
problem in the model code and solved it. This problem had been present and unsolved for
years.
Placed again into full-time software sustainment of the MMSP profiler.
Managed the SDF for a new profiler software release, and assisted in the development of that
new release. Primarily independently, upgraded the MMSP modeling computer to RHEL 6.0.
Set up a Solaris 10 build machine for the new profiler.
Designed, developed, and tested, primarily independently, the code necessary to allow the
MMSP profiler to handle two types of GRIB data, and presented a code walk through. Found
seven errors in the profiler code written by the OEM. C++, csh, sh, and Perl were utilized for a
Solaris OS computer among a system of three networked computers.
Helped to set up a Solaris 8 build machine for an older version of the profiler. Assisted with
putting the software transition of the profiler (18,000 files) from the OEM to the FSED under
CM control.
Developed algorithms, programs, and shell scripts to analyze radar detection data and
debugging output data for the LCMR/Q48. Deduced logical, statistical data analysis issues
with mathematical proof in C++ radar code written by the OEM. Assisted with the algorithm
to detect rockets with the LCMR.
Wrote an 87-page document describing how to playback recordings using the process
automation programs and shell scripts I independently developed for a Linux OS. By affecting
synchronization of the interface computer and radar cylinder computer, more insight was
obtained into the various software modules of the entire system. With these methods, a bug
manifested by timing discrepancies between the two computers was detected in the LCMR
system.
Successfully completed the Modern Radar Systems and Phased Arrays Radar short courses
from Georgia Institute of Technology.
Was invited to create and program an algorithm to predict the current likelihood of obtaining
the correct FY-end planned effort based on the current actual effort for larger contracted
projects. My solution was selected over those offered by the section managers. The algorithm
provides simple, visual evidence of the likelihood of future success obtaining the correct FYend planned effort every pay period. The original, complex mathematical and statistical
algorithm is the primary indicator of the status of each project. This algorithm and several
simple, supplemental algorithms provided by several section managers were approved by the
government and have been utilized since 2009. Programmed the entire solution for WINXP
Pro in C using MSVS C++ express and wrote a 60-page user’s manual for this program. A senior
engineer, my former team leader, attempted to program this solution in Java and could not.
Took the personal software process (PSP) fundamentals and advanced courses of the SEI,
Carnegie Mellon University, over a 2-week period in August 2009.
Wrote a 156-page, single-spaced description of one run through the entire weather prediction
algorithm for the laptop profiler. Wrote a document describing the corrections I made to the
laptop software.
Researched the new WRF weather model as compared to the MM5 model. Developed a plan
to upgrade the laptop profiler software with a more modern weather model. CGI obtained
funding for this task in 2012 for the CMDP.
Independently, tested and debugged the prototype laptop profiler in conjunction with the
currently fielded profiler by comparing numerical output within various identical modules of
the systems. These comparisons revealed many issues in both systems. Corrected
(Unix/Linux/FORTRAN 77) code for most software modules of the laptop profiler before the
project ended.
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Began maintenance of the MMSP. Studied Java several months.
Computers (OS): x86 (WINXP Pro, Vista Enterprise, and Windows 7 Pro Enterprise); (Dell Dual
Core laptop, RHEL 2.6); (VMware, VT Miltope); (RHL Fedora 5, Solaris 7); (RHEL 5.5, Solaris 8);
(RHEL 6.0, Solaris 10).
Programming and scripting languages: C, C++, FORTRAN 77 and 90, in Linux and Solaris;
WINXP/MSVS/C++ express C; Linux/Solaris/sh, csh; Linux/bash; Solaris/Perl.
07/05-04/08
Staff Scientist
Washington University School of Medicine, Heart Rate Variability Laboratory, Department of
Internal Medicine, Cardiovascular Consultants, Campus Box 8086, 13th floor Northwest Tower,
660 S. Euclid Ave. St. Louis, MO 63110.
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I developed about 80% of the research methods/tools that are still being used in 2014: cf.
hrv.wustl.edu; www.hrvconsultants.com.
Independently, on 01/08/08, repaired the qrsdk.c program of GE-Marquette. The program
had intermittently caused misalignment of the detected QRS-complex peaks and the actual
ECG-QRS-complex peaks for more than a decade due to unexpected characters in the
beginning of the binary QRS file output by the scanner.
Independently designed and programmed a 48,000-line Heart Rate Variability (HRV) analysis
program (UNIX/Cygwin/C)(gcc). HRV is a mathematical time series analysis of annotated
cardiac inter-beat intervals. Completed the mathematics for all of the many new algorithms
included in the program. Features are: 1) Easy variable selection. 2) Easy analysis period
selection. 3) Automatic placement of results in a .csv spreadsheet. 4) HRV analyses methods
for sleep and physiological studies. 5) 700 epoch-averaged or total-recording variables. 6)
140 adjustable parameters. 7) HRV analyses of ECG and EEG signals. 8) Automatic
concatenation of results while running in batch mode. 9) Computation of time- and
frequency-domain, and nonlinear variables. 10) Inclusion of several original methods of
analyses, 11) Multithreading option.
Programmed the Detrended Fluctuation Analysis (DFA) algorithm (UNIX/Cygwin/C).
Discovered an error in the code of the original authors’ version posted on www.physionet.org.
The web site acknowledges the discovery in the program’s documentation.
Independently designed and programmed (UNIX/Cygwin/C) a method to line up R-wave peak
times of QRS complexes in RR-interval beat files with the correct R-wave peak times in the
ECG. Recorder and scanner errors caused misalignment. The method can align RR-interval
beat files with ECG’s of various sampling rates.
Upgraded the HrvInteractive (MSVS2005Pro/MFC/C++) GUI described below. The lab utilizes
HrvInteractive extensively to find in-bed/out-of-bed times from graphically displayed HRV
plots over a 24-hour period.
Wrote shell scripts and programs to prepare and load the text ECG’s for scanning on a GEMarquette MARS PC (WINXP) Holter (ambulatory ECG recorder) scanner and a Cardioscan
Holter scanner.
Completed the writing of MATLAB code necessary to automate the running of the QT-segment
variability index (QTVI) program developed at Johns Hopkins Medical School.
Collected data from heart transplant patients on my personal time until about 07/2007.
Approximately 500 ECG’s were collected.
Part-time UNIX system administration.
07/03-06/05
Research Associate
Washington University School of Medicine, Heart Rate Variability Laboratory. Job, title, and
seniority (since 03/96) transferred to the HRV Lab from Barnes-Jewish Hospital (BJH).
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Independently designed and programmed (UNIX/C) methods to automate the extraction of
data for HRV analyses of scanned Holter recordings for the SAGE drug study.
Independently designed and programmed (UNIX/C) methods to compute HRV data for
unusual studies: 1) HRV of mice. 2) HRV of anxiety and consequent work injuries of
professional musicians. 3) HRV anxiety studies of subjects during various sleep stages.
Migrated the HrvInteractive GUI to (MSVS2003Pro/MFC/C++) from MSVC++ 6 standard
edition. Designed and programmed additional capabilities in the GUI, independently.
Collected data from heart transplant patients on my personal time.
Part-time UNIX system administration.
07/98-06/03
Research Associate
Barnes-Jewish Hospital, Department of Internal Medicine, Division of Cardiology, 1 Barnes
Jewish Hospital Plaza, St Louis, MO 63110.
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Independently designed and programmed software (UNIX/Linux/C) to read various
commercial binary formats of ECG’s and the EDF format of polysomnograms for conversion
to text. Wrote shell scripts and programs to prepare and load the text ECG’s for scanning on a
GE-Marquette MARS 8000 Holter scanner (Solaris 6).
Designed and programmed, independently, (UNIX/Cygwin/C) the automation of the HRV
analyses of the TAKEDA drug study. Automation began with the extraction of ECG’s with a
Delmar Medical Systems’ Impresario Holter scanner. Automation ended with Holter scanning
on the MARS 8000 and then HRV analyses.
Independently designed and programmed an HRV interactive GUI (MSVC++ 6/MFC/C++),
called HrvInteractive, using a 4-pane dynamic splitter window, the single document interface,
and the document/view architecture. The GUI currently provides 270 different four-paned
views, along with one- and two-paned views. Segments can be quickly viewed for up to 24
hours of data. There are 59 adjustable parameters. HrvInteractive also contains: 1) Time- and
frequency-domain HRV. 2) Nonlinear HRV. 3) 720 different segment lengths. 4) An editable
sleep apnea detector based on heart rate. 5) An HRV application to determine in-bed/out-ofbed times using 13 different views. Independently designed and programmed the algorithms
for sleep apnea detection. Independently designed and programmed all of the graphical
representations of HRV data.
Independently designed and programmed, for short recordings from heart transplant
recipients: 1) A fully automated 1000 Hz ECG scanner (UNIX/Linux/DOS/C). 2) Algorithms for
QRS signal averaging. 3) Algorithms to detect cardiac allograft rejection directly from the ECG
signal.
Received additional funding by the BJH Foundation for and carried out research in cardiac
rejection detection for cardiac transplant recipients using HRV and signal processing
analyses. The funding lasted one year. Afterwards, collected data from heart transplant
patients on my personal time.
Independently designed and programmed (UNIX/DOS/C) an ECG scanner that detected Rwave peaks and allowed interactive editing of the R-wave peak locations and beat labels,
while using only 64KB of RAM. Applied the scanner to ECG’s obtained from polysomnograms
of patients with suspected sleep apnea. Analysis of the output of this scanner was used obtain
a $3,000,000 grant by Robert M. Carney, a psychologist. Scanning for some of the unusual HRV
projects mentioned above required this ECG scanner.
Designed and programmed algorithms (UNIX/C) for the analysis of HRV data of various
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patient populations. Programmed algorithms from original research articles. Enhanced HRV
code by including new signal processing, data processing, and numerical algorithms.
Designed and programmed shell scripts and C programs to automate data processing.
Invented an algorithm to detect exceptionally high HRV (assumed erratic sinus rhythm).
Independently designed and programmed algorithms for the automatic detection of sleep
apnea (DOS/C). Designed and programmed a sleep apnea scanner similar to the previously
mentioned ECG scanner that used 64KB of RAM. Designed and programmed a plot of 24-hour
heart rate tachograms (UNIX/Cygwin/C). The lab uses the tachogram extensively. Developed
an easy method to detect sleep apnea with these tachograms. Cardioscan, owned by Bill
Parsons, utilizes the tachogram and easy sleep apnea detection method.
Part-time UNIX system administration beginning in the year 2000.
01/01-06/01
Remote, Part-time, Temporary Computer Programming Consultant
Itamar Medical Ltd., 9 Halamish Street, PO Box 3579, Caesarea, 38900 Israel.
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Independently designed and programmed the analysis of experimental data obtained from a
pulse arterial tonometer (PAT) device placed on the tip of a subject’s finger. The software was
written using (DOS/C).
01/97-06/98
Research Technician II
Barnes-Jewish Hospital, Department of Internal Medicine, Division of Cardiology.
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Independently derived the mathematics and programmed univariate Cox and logistic
regression statistical algorithms (UNIX/C). Showed that high HRV predicts mortality in postmyocardial infarction patients.
Independently programmed: 1) Algorithms from nonlinear dynamics. 2) Csh scripts for batch
jobs. 3) Algorithms for the statistical analysis and/or manipulation of output data (UNIX/C).
All algorithms were utilized for the analysis of clinical data. Programmed in the SAS statistical
programming language to analyze data.
Obtained a grant from the BJH Foundation to detect acute rejection in cardiac transplant
patients using heart rate variability analyses.
01/97-04/98
Remote, Part-time, Temporary Computer Programming Consultant
Department of Psychology, University of Missouri in Columbia, 210 McAlester Hall, Columbia,
MO 65211
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Independently designed and programmed an HRV analysis package (UNIX/Linux/DOS/C) that
included: 1) Five autoregressive spectral analyses algorithms. 2) A smoothed-pseudo-WignerVille time-frequency analysis algorithm. 3) Spectral decomposition for the autoregressive
analysis. 4) Statistical algorithms for the validation of the autoregressive models. 5) HRV timedomain algorithms. 6) Algorithms from nonlinear dynamics. 7) Algorithms for statistical
analysis and/or further processing of the output data. 8) Utilization of only 64 KB of RAM.
Autoregression, FFT, and filtering algorithms were translated from FORTRAN 77. Tested code.
Completed the mathematics for the statistical analyses, spectral decomposition, and timefrequency analyses. The National Institutes of Health later purchased the software. Very many
publications have been produced with this code.
Education:
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Southern Illinois University, Edwardsville, IL; B.S. Mathematics; 08/31/1978; GPA: 4.42/5.0
(3.54/4.0).
 Southern Illinois University, Edwardsville; (All but Master's Degree thesis) Physics; 05/1980;
GPA: 4.88/5.0 (3.90/4.0).
 Washington University, St. Louis, MO; M.A. Physics; 05/21/1982; GPA: 3.18/4.0.
 Washington University, St. Louis, MO; Ph.D. Physics; 12/19/1991; GPA: 3.34/4.0.
 Eberhard-Karls Universität Tübingen, Tübingen, Germany; Institute for Theoretical Physics;
PostDoctoral Fellowship; 04/1992 –08/1993and (part-time: 09/1993 –12/1993).
 University of Missouri, St. Louis; 36 semester hours toward a M.Ed. in Sec. Ed. plus a
Mathematics teaching certification (Also took several advanced math classes.); 01/1994 –
12/1995; GPA: 3.83/4.0.
Dissertation:
Spectral Functions and the Validity of the Shell Model in Finite Nuclei. After working on my
dissertation for four years, in1986, I changed from a dissertation in Low Temperature Experimental
Physics to one in Nuclear Many Body Theory.
Honors/Awards:
B.S. with honors, 1978; Illinois State Scholar, 1974-1978; πμε honorary Mathematics
Fraternity, Southern Illinois University; Washington University Fellow, 1982-1985. In 2008, Who’s
Who in America invited me to submit my biography, and I did not.
Salary Requirements:
Negotiable. Relocation assistance is desired if applicable.
Visa Status:
I am an American citizen, born in Granite City, IL (20 minutes from downtown St. Louis, MO).
Availability:
I am available May 15, 2016 for local positions. For positions requiring relocation, several
months are required.
Location Preferences:
OK (Lawton), OKC; MO (St. Louis); SC (Charleston); FL (Miami, Orlando); CA (SF, coast); WA
(coast); OR (coast); Germany (Southwest, West, South).
Summary of System Administration and Mathematics Experience as of 4/1/2008:
For nine of the past twelve years, in the HRV lab, I was the only person with knowledge of
computer programming. Also in the HRV lab, I was the only person capable of doing sophisticated
mathematical calculations. Between 1975 and 1994, I have been studying or regularly doing
advanced mathematics. In 1991, I significantly improved the Levenberg-MarQuardt algorithm by
finding a much better estimate of the global minimum, while gaining professional programming
experience in (Unix/C). From 1995 to March 2008, I have occasionally done advanced mathematics
on the job.
I have been the part-time UNIX/Linux system administrator for 8 years in the HRV lab. I
managed one RHL 7.3 server, one Solaris 7 server, and two Solaris 8 servers. The servers were an IBM
PC, a Sun SPARCstation 5, a Sun Ultra Enterprise 450, and a Sun Ultra 60, respectively. I also spent years
administrating the x86 PC’s (WIN95, WIN98, WIN2000 Pro, WINXP Pro) in the lab.
Publication List: http://ppdomitrovich.proinbox.com/ppdomitrovich/List_Of_Publications.html
List of Publications
PUBLISHED ARTICLES:
1. Dickhoff WH, Domitrovich PP, Polls A, Ramos A. The Foundation of the Nuclear Shell model.
Condensed Matter Theories, Vol.5, V.C. Aguilera-Navarro, ed., (Plenum, New York, 1990,
pp.275-83).
2. Dickhoff WH, Domitrovich PP, Allaart K, Brand MGE, Muller FA, Rijsdijk G, Polls A, Ramos A.
Generalized Spectral Functions and the Validity of the Shell Model. Two Nucleon Emission
Reactions, O. Benhar and A. Fabrocini, eds., (ETS Editrice, Pisa, 1991, pp.332-47).
3. Domitrovich PP, Bückers D, Müther H. Nambu-Jona--Lasinio Models beyond the Mean-Field
Approximation. Phys Rev C 48(1), 1993, pp. 413-22. PMID: 9968835.
4. Domitrovich PP, Müther H. On the Analytic Structure of the Quark Self-Energy in NJL Models.
J Phys G 20(12), 1994, pp. 1885-1900.
5. Hogue CW, Domitrovich PP, Stein PK, Despotis GD, Re L, Shuessler RB, Kleiger RE, Rottman
JN. RR Interval Dynamics Prior to Atrial Fibrillation in Patients after Coronary Artery Bypass
Graft Surgery. Circulation 98, 1998, pp. 429-34. PMID: 9714093.
6. Stein PK, Ehsani AA, Domitrovich PP, Kleiger RE, Rottman JN. The Effect of Exercise Training
Heart Rate Variability in Healthy Older Adults. Am Heart J 138(3), Sept 1999, Part 1, pp. 56776. PMID: 10467210.
7. Stein PK, Hagley MT, Cole PA, Domitrovich PP, Kleiger RE, and Rottman JN. Changes in Heart
Rate Variability during Normal Pregnancy. Am J Obstet Gynecol 180(4), April 1999, pp. 97885, PMID: 10203667.
8. Bilge AR, Stein PK, Domitrovich PP, Gérard PL, Rottman JN, Kleiger RE, Kulbertus HE, Piérard
LA. Alternative Methods for Assessing the Ultra-Low Frequency Component of Heart Rate
Variability: Application to Clinical Recordings. Intl J of Cardiol 71, 1999, pp. 1-6. PMID:
10522558.
9. Stein PK, Domitrovich PP, Kleiger RE, Rottman JN. Clinical and Demographic Determinants
of HRV in Post-MI Patients: Insights from the Cardiac Arrhythmia Suppression Trial (CAST).
Clin Cardiol 23(2), Mar 2000, pp. 187-94. PMID: 10761807.
10. Stein PK and Domitrovich PP. Detecting OSAHS from Patterns Seen on Heart-Rate
Tachograms. Computers in Cardiology 27, 2000, pp. 271-4.
11. Stein PK, Schmeig RE, Jr., El-Fouly A, Domitrovich P, Buchman TG. Association between Heart
Rate Variability Recorded on Post-Operative Day One and Length of Stay in Abdominal Aortic
Surgery Patients. Crit Care Med 29(9), Sept 2001, pp. 1738-43. PMID: 11546974.
12. Hogue CW, Talke P, Stein PK, Richardson C, Domitrovich PP, Sessler DI. Autonomic Nervous
System Responses during Sedative Infusions of Dexmedetomidine Anesthesiology 97(3), Sept
2002, pp. 592-8. PMID: 12218525.
13. Stein PK, Yanez D, Domitrovich PP, Gottdiener JS, Chaves P, Kronmal RA, Rautaharju PM.
Heart Rate Variability is Confounded by the Presence of Erratic Sinus Rhythm. Computers in
Cardiology 29, 2002, pp. 669-72.
14. Domitrovich PP, Stein PK. A New Method To Detect Erratic Sinus Rhythm In RR-Interval Files
Generated From Holter Recordings. Computers in Cardiology 29, 2002, pp. 665-8.
15. Williams C, Stein PK, Domitrovich PP. Feasibility of a Simple Method for Identifying Sleep
Periods from Holter Recordings. Computers in Cardiology 29, 2002, pp. 533-6.
16. Stein PK, Duntley SP, Domitrovich PP, Nishith P, Carney RM. A Simple Method for Detecting
Sleep-Disordered Breathing Using Holter Monitoring. J Cardiovasc Electrophysiol 14(5), May
2003, pp. 467-73. PMID: 12776861.
17. Nishith P, Duntley SP, Domitrovich PP, Uhles ML, Cook BH, Stein PK. Effect of Cognitive
Behavioral Therapy on Heart Rate Variability during REM Sleep in Female Rape Victims
Diagnosed with PTSD. J Trauma Stress 16(3), June 2003, pp. 247-50. PMID: 12816336.
18. Stein PK, Domitrovich PP, Kleiger RE. Including Patients with Diabetes or CABG Decreases
the Association Between Heart Rate Variability and Mortality Post-MI. Am Heart J 147(2), Feb
2004, pp. 309-16. PMID: 14760330.
19. Stein PK, Hui N, Domitrovich PP, Gottdiener JS, Rautaharju PM. Distinguishing Normal and
Abnormal HRV Using Graphical and Non-Linear Analyses. Computers in Cardiology 31, 2004,
pp. 205-8.
20. Stein PK, Domitrovich PP, Ambrose K, Lyden A, Fine M, Gracely RH, Clauw DJ. Gender Effects
on Heart Rate Variability in Fibromyalgia and Gulf War Illness. Arthritis Rheum 51(5), Oct
2004, 700-8. PMID: 15478168.
21. Stein PK, Domitrovich PP, Huikuri HV, Kleiger RE, the CAST Investigators. Traditional and
Nonlinear Heart Rate Variability are Each Independently Associated with Mortality after
Myocardial Infarction. J Cardiovasc Electrophysiol 16(8), Jan 2005, No 1, pp. 13-20. PMID:
15673380.
22. Carney RM, Blumenthal JA, Freedland KE, Stein PK, Howells WB, Berkman LF, Watkins LL,
Czajkowski SM, Hayano J, Domitrovich PP, Jaffe AS. Low Heart Rate Variability and the Effect
of Depression on Post-MI Mortality. Arch Intern Med 165(13), July 2005, pp. 1486-91. PMID:
16009863.
23. Stein PK, Domitrovich PP, Hui N, Rautaharju PM, Gottdiener JS. Sometimes Higher Heart Rate
Variability is Not Better Heart Rate Variability: Results of Graphical and Non-Linear Analyses.
J Cardiovasc Electrophysiol 16(9), Sep. 2005, pp. 954-9. PMID: 16174015.
24. Stein PK, Lundequam EJ, Clauw DJ, Freedland KE, Domitrovich PP. Circadian and Ultradian
Rhythms in Cardiac Autonomic Modulation. IEEE Eng Med Bio Soc, 28th Ann Int Conf IEEE,
2006, pp. 429-32. PMID: 17946831.
25. Stein PK, Domitrovich PP, Lundequam EJ, Duntley SP, Freedland KE, Carney RM. Circadian
and Ultradian Rhythms in Heart Rate Variability. Biomed Tech 51(4) (Berl), 2006, pp. 155-8.
PMID: 17061928.
26. Carney RM, Howells WB, Blumenthal JA, Freedland KE, Stein PK, Berkman LF, Watkins LL,
Czajkowski SM, Steinmeyer B, Hayano J, Domitrovich PP, Burg MM, Jaffee AS. Heart Rate
Turbulence, Depression, and Survival after Acute Myocardial Infarction. Psychosom Med
69(1), Jan 2007, pp. 4-9. (Epub 2006 Dec 13.) PMID: 17167127.
27. Stein PK, Tereschenko L, Domitrovich PP, Perez A, Deedwania P. Diastolic Dysfunction and
Autonomic Abnormalities in Patients with Systolic Heart Failure. Eur J Heart Fail 9(4), April
2007, pp. 364-9. (Epub 2006 Nov 22.) PMID: 17123863.
28. Stein PK, Barzilay JI, Domitrovich PP, Chaves PM, Gottdiener JS, Heckbert SR, Kronmal RA.
The Relationship of Heart Rate and Heart Rate Variability to Non-Diabetic Fasting Glucose
Levels and the Metabolic Syndrome: The Cardiovascular Health Study. Diabet Med 24(8), Aug
2007, pp. 855-63. (Epub 2007 Apr 2.) PMID: 17403115.
29. Domitrovich PP. A Graphical User Interface for the Study of Heart Rate Variability.
Computers
in
Cardiology
34,
2007,
pp.
469-72.
http://www.cinc.org/Proceedings/2007/pdf/0469.pdf
30. Stein PK, Cohen RJ, Devlin NM, Lundequam EM, Domitrovich PP, Gottdiener JM, Redline S.
Cyclic Variation of Heart Rate During Sleep in Four Recordings of Up to 13 Years in Elderly
Adults. Computers in Cardiology 34, 2007, pp. 33-5.
31. Stein PK, Cohen RJ, Mau B, Domitrovich PP, Gottdiener JM, Redline S. A Comparison of Holterand Polysomnogram-Based Detection of Bed and Wake Times. Computers in Cardiology 34,
2007, pp. 697-700.
32. Stein PK, Lundequam EJ, Oliveira LP, Clauw DJ, Freedland KE, Carney RM, Domitrovich PP.
Cardiac Autonomic Modulation. Analyzing Circadian and Ultradian Rhythms. IEEE Eng Med
Biol Mag. 2007 Nov-Dec;26(6):14-8. BMID: 18189081.
33. Watanabe MA, Bhalodia R, Lundequam EJ, Domitrovich PP, Steinmeyer BC, Stein PK,
Freedland KE, Duntley SP, Carney RM. Increased Ventricular Premature Contraction
Frequency During REM Sleep in Patients with Coronary Artery Disease and Obstructive Sleep
Apnea. Ind Pacing and Electrophys J. 2008;8(4):258-67. PMCID: PMC2572026.
34. Stein PK, Barzilay JI, Chaves PHM; Traber J, Domitrovich PP, Heckbert SR, Gottdiener JS.
Higher Levels of Inflammation Factors and Greater Insulin Resistance are Independently
Associated with Higher Heart Rate and Lower Heart Rate Variability in Normoglycemic Older
Individuals: The Cardiovascular Health Study. J Am Geriatric Soc. 2008;56(2):315-21. PMID:
18179502.
35. Stein PK, Le Q, Domitrovich PP. Development of More Erratic Heart Rate Patterns is
Associated with Mortality Post-Myocardial Infarction. J Electrocard. 2008;41(2):110-5.
PMCID: PMC2323590.
36. Hoyer D, Friedrich H, Stein PK, Domitrovich PP, Hoyer H, Faldu C, Buchman TG. Autonomic
Information Flow Improves Prognostic Value of Heart Rate Patterns After Abdominal Aortic
Surgery. J Crit Care. 2008;23(2):255-62. PMID: 18538221.
37. Carney RM, Steinmeyer B, Freedland KE, Blumenthal JA, Stein PK, Steinhoff WA, Howells WB,
Berkman LF, Watkins LL, Czajkowski SM, Domitrovich PP, Burg MM, Hayano J, Jaffe AS.
Nighttime Heart Rate and Survival in Depressed Patients Post Acute Myocardial Infarction.
Psychosomatic Med. 2008;70(7):757-63. PMID: 18725430.
38. Stein PK, Sanghavi D, Domitrovich PP, Mackey RA, Deedwania P. Ambulatory ECG-based Twave Alternans Predicts Sudden Cardiac Death in High-Risk Post-MI Patients with Left
Ventricular Dysfunction in the EPHESUS Study. J Cardiovasc Electrophys, 2008;19(10):103742. PMID: 18554193.
39. Stein PK, Barzilay JI, Chaves PHM, Mistretta SQ, Domitrovich PP, Gottdiener JS, Rich MW,
Kleiger RE. Novel Measures of Heart Rate Variability Predict Cardiovascular Mortality in Older
Adults Independent of Traditional Cardiovascular Risk Factors: The Cardiovascular Health
Study (CHS). J Cardiovasc Electrophys. 2008;19(11):1169-74. PMID: 18631274.
40. Stein PK, Barzilay JI, Chaves PHM, Domitrovich PP, Gottdiener JS. Heart Rate Variability and
Its Changes Over 5 Years in Older Adults. Age and Ageing. 2008;38(2):212-8. PMCID:
PMC2724889.
41. Tereshchenko LG, Fetics BJ, Domitrovich PP, Lindsay BD, Berger RD. Prediction of Ventricular
Tachyarrhythmias by Intracardiac Repolarization Variability Analysis. Circulation: Arrhyth
and Electrophys. 2009;2(3):276-84. PMID: 19808478.
PUBLISHED ABSTRACTS:
1. Stein PK, Domitrovich PP, Freedland KE, Skala JA, Carney RM, Kleiger RE, Rottman JN. Heart
Rate Variability Indices during Hospitalization for Acute CHF and One-Year Risk of All-Cause
Mortality. J Heart Failure 4, 1997, Abs., p. 33.
2. Hogue Jr. CW, Domitrovich PP, Stein PK, Despotis GD, and Rottman JN. Atrial Fibrillation Risk
after CABG is Associated with Altered Heart Rate Dynamics. Anesthesiology 87, 1997, Abs., p.
A129.
3. Stein PK, Domitrovich PP, Kleiger RE, Rottman JN. Decreased Baseline Heart Rate Variability
Predicts Mortality in CAST. Circulation 96(8), Oct. 1997, Suppl. I, p. 653.
4. Stein PK, Domitrovich PP, Kleiger RE, Rottman JN. Heart Rate Variability After Treatment
with Type IC Antiarrhythmics Predicts Mortality in CAST. Circulation 96(8), Oct 1997, Suppl.
I, p. 716.
5. Kleiger RE, Stein PK, Domitrovich PP, Rottman JN. Association between Changes in HRV from
Baseline to Suppression: Holters and Mortality in CAST. PACE (NASPE) 21, April 1998, Part II,
p. 821.
6. Kleiger RE, Stein PK, Domitrovich PP, Rottman JN. Effect of Treatment with Type Ic
Antiarrhythmics on Heart Rate Variability in CAST. PACE (NASPE) 21, April 1998, Part II, p.
822.
7. Stein PK, Domitrovich PP, Kleiger RE, Rottman JN. Baseline Heart Rate Variability after CABG
or PTCA in CAST. Annals of Noninvasive Electrocard 3(3), 1998, Abs., p. S45.
8. Kleiger RE, Stein PK, Domitrovich PP, Rottman JN. CABG and Diabetes Confound HRV
Prediction of Mortality Post-MI. PACE (NASPE) 22, April 1999, Part II, p. 790.
9. Stein PK, Domitrovich PP, Shectman KB, Kleiger RE, Rottman JN. Increased Short-term RRInterval Variability Associated with Abnormal Spectral Patterns Predicts Mortality in the
Cardiac Arrhythmia Suppression Trial. Circulation 100(18), Nov 1999, Suppl. I, p. 158.
10. Stein PK, Schmeig RE, El-Foley A, Domitrovich PP, and Buchman TG. Heart Rate Variability
and Length of Stay in Abdominal Aortic Surgery Patients. Soc Crit Care Med. Symposium,
2000, Abs.
11. Carney RM, Stein PK, Freedland KE, Domitrovich PP, Duntley SP. Sleep Apnea and Depression
after Myocardial Infarction. J Psychosom Med 62(1), 2000, Abs., p. 110.
12. Domitrovich PP, Rogers, JG, Ewald GA, Stein PK, Rottman JN, Kleiger RE. Acute Cardiac
Allograft Rejection Detection Using Electrocardiogram-Based Analyses. Transplantation
60(8), 2000, Suppl., p. S230.
13. Domitrovich PP, Stein PK, Freedland KE, Skala JA, Rottman JN, Kleiger RE. Differences in
Heart Rate Complexity among Post-MI and CHF Patients and Normal Controls. Circulation
102(18), Oct 2000, Suppl. II, p. 494.
14. Stein PK, Domitrovich PP, Makikallio TH, Huikuri HV, Kleiger RE. Nonlinear but not TimeDomain Indices of Heart Rate Variability Predict Mortality in the Cardiac Arrhythmia
Suppression Trial (CAST). Circulation 102(18), Oct 2000, Suppl. II, p. 493.
15. Stein PK, Duntley SP, Domitrovich PP, Stuckey M, Uhles ML, Nishith P, Carney RM. A Simple
Method for Detecting Possible Obstructive Sleep-Apnea Hypopnea Syndrome from Holter
Recordings. Internat Symposium on Sleep and Autonomous Function. Marburg, Germany.
Somnology 5(2), 2001, Suppl.
16. Stein PK, Duntley SP, Domitrovich PP, Young M, Uhles ML, Nishith P, Carney RM. Patients
Undergoing Routine Holter Monitoring Can Simultaneously Be Screened for Obstructive Sleep
Apnea-Hypopnea Syndrome Using a Simple Technique. Circulation 104(17), Oct 2001, Suppl.
II, p. 602.
17. Gottdiener JS, Stein PK, Domitrovich PP, Kitzam DW. Time and Frequency Domain and NonLinear Heart Rate Variability in Diastolic and Systolic Congestive Heart Failure of the Elderly:
The Cardiovascular Health Study. Circulation 106(19), Nov 2002, Suppl. II, p. 648.
18. Nishith P, Duntley SP, Smith B, Uhles M, Domitrovich PP, Stein PK, Morissey M. Sleep
Functioning in Treatment-Seeking Female Rape Victims Diagnosed with PTSD. Sleep 26, Nov
2003, Abs. Suppl., p. A383.
19. Stein PK, Tereschenko L, Perez A, Domitrovich PP, Deedwania P. Diabetic Patients with Heart
Failure Have Great Derangement of Cardiac Autonomic Function as Assessed by Heart Rate
Variability Parameters. Circulation 110(17), Oct 2004, Suppl. III, p. 456.
20. Stein PK, Domitrovich PP, Gottdiener JS, Rautaharyu PM. The Combination of Short-Term
Fractal Scaling Exponent and Decreased High Frequency Power Provides a Powerful
Independent Predictor of Mortality in the Elderly. Circulation 110(17), Oct 2004, Suppl. III, p.
457.
21. Tereschenko L, Stein PK, Perez A, Domitrovich PP, Deedwania P. Severe Diastolic Dysfunction
is Associated with Greater Autonomic Function Abnormalities as Assessed by Heart Rate
Variability in Patients with Stable Systolic Heart Failure. Circulation 110(17), Oct 2004, Suppl.
III, p. 634.
22. Domitrovich PP, Pigeon WR, Stein PK, Perls ML. Heart Rate Variability in Patients with
Insomnia and Good Sleeper Controls. Sleep 27, 2004, Abs. Suppl., p. A269.
23. Stein PK, Sootedehnia N, Domitrovich PP, Larson E, Siscovick D, Gottdiener JS, Rautaharyu
PM. Abnormal Heart Rate Variability is Significantly Associated with Sudden Cardiac Death
Among the Community-Dwelling Elderly. J Am Col Card 45, Feb 2005, Abs. Suppl., p. 126A.
24. Stein PK, Barzilay JI, Gottdiener JS, Domitrovich PP, Rautaharju PM, Heckbert SR, Kronmal
RA. Heart Rate Variability, Glucose Intolerance and the Metabolic Syndrome in the Elderly:
The Cardiovascular Health Study. Circulation 112(17), Oct 2005, Suppl. II, p. 827.
25. Gottdiener JS, Stein PK, Domitrovich PP, Rautaharju PM. Association of Heart Rate Variability
with Heart Failure Symptoms in the Elderly: The Cardiovascular Health Study. Circulation
112(17), Oct 2005, Suppl. II, p. 774.
26. Stein PK, Lundequam EJ, Howells WB, Duntley SP, Domitrovich PP, Freedland KE, Carney RM.
Characteristics of Heart Rate Changes in Response to Sleep-Disordered Breathing Among
Cardiac Patients. J Am Col Card 47, Feb 2006, Abs. Suppl., p. 27A.
27. Barzilay JI, Stein PK, Gottdiener JS, Domitrovich PP, Rautaharju PM, Heckbert SR, Kronmal
RA. Inflammation is Independently Associated with Diminished Heart Rate Variability in
Glucose Intolerant Older Adults: The Cardiovascular Health Study. Meeting of the 3rd Int. Conf.
on Insulin Resistance, Nov 2005, San Francisco, CA, Abs. A-292.
28. Stein PK, Barzilay JI, Domitrovich PP, Chaves PH, Gottdiener JS, Rich MW, Rautaharju PM,
Kleiger RE, Kronmal RA. Abnormal Heart Rate Variability is a Powerful Independent Predictor
of Long-Term Cardiovascular Mortality in the Elderly: The Cardiovascular Health Study. J Am
Col Card 47, Feb 2006, Abs. Suppl., p. 29A.
29. Bhalodia R, Domitrovich PP, Carney RM, Stein PK, Watanabe MA. Patients with Severe Sleep
Apnea Have Increased and Altered Sleep Stage Distribution of Ventricular Premature
Contraction Frequency. Circulation 114(18), Oct 2006, Suppl. II, p. 472.
30. Stein PK, Lundequam EJ, Domitrovich PP, Yonamine AJ, Redline S. Cyclic Heart Rate Patterns
are Variability Associated with REM and Wake cycles in the Elderly. Sleep 29, 2006, Abs.
Suppl., p. A30.
31. Stein PK, Lundequam EJ, Howells WB, Duntley SP, Domitrovich PP, Freedland KE, Carney RM.
Determinants of Heart Rate Accelerations in Response to Sleep-Disordered Breathing Among
Cardiac Patients. Sleep 29, 2006, Abs. Suppl., p. A160.
32. Gallucci MA, Lichtman SW, Wanstall DA, King ML, Pellicone JT, Stein PK, Domitrovich P, De
Meersman R. Effects of An Outpatient Pulmonary Rehabilitation Program on Heart Rate
Variability and Right Heart Function in Patients With Chronic Obstructive Pulmonary Disease.
J Cardiopul Rehab and Prev 26(4), July/Aug 2006, p. 257.
33. Stein PK, Oliveira L, Domitrovich PP, Lundequam EJ, Redline S. Changes in Nighttime
Ultradian Parameters of Heart Rate Over Time in the Elderly. Sleep 30, 2007, Abs. Suppl., p.
A59.
34. Stein PK, Domitrovich PP, Lundequam EJ, Redline S. Decreased Heart Rate Variability from
Polysomnography Predicts Mortality in the Elderly. Sleep 30, 2007, Abs. Suppl., p. A110.
PRESENTATIONS:
1. Domitrovich PP, Müther H. Beyond Hartree-Fock in the Nambu-Jona--Lasinio Model. Meeting
of the German Physical Society, Mainz, Germany, Mar 1993.
2. Domitrovich PP, Rogers, JG, Ewald GA, Stein PK, Rottman JN, and Kleiger RE. Acute Cardiac
Allograft Rejection Detection Using Electrocardiogram-Based Analyses. Poster presentation.
Transplant 2000, May 2000, Chicago IL, U.S.A.
3. Domitrovich PP, Stein PK, Freedland KE, Skala JE, Rottman JR, Kleiger RE. Differences in
Heart Rate Complexity among Post-MI and CHF Patients and Normal Controls. Oral
presentation. Scientific Sessions 2000 of the AHA, Nov 2000, New Orleans, Louisiana, U.S.A.
4. Domitrovich PP, Stein PK. A New Method to Detect Erratic Sinus Rhythm in RR-Interval Files
Generated from Holter Recordings. Computers in Cardiology Conference, Sept 2002,
Memphis, Tennessee, U.S.A.
5. Domitrovich PP. A Graphical User Interface for the Study of Heart Rate Variability.
Computers in Cardiology Conference, October 2007, Durham, North Carolina, U.S.A.