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Kigali Institute of Science and Technology Institut des Sciences et de Technologie de Kigali Avenue de l'Armée, B.P. 3900 Kigali, Rwanda INSTITUTE EXAMINATIONS – ACADEMIC YEAR 2012 - 2013 SUPPLEMENTARY EXAMINATION FACULTY OF SCIENCE SCIENCE 3: APPLIED BIOLOGY FOURTH YEAR SEMESTER II BIO 3421: EPIDEMIOLOGY OF INFECTIOUS DISEASES: Date: ---/---/2013 TIME: 2 HOURs MAXIMUM MARKS = 60 _____________________________________________________________________ INSTRUCTIONS 1. 2. 3. 4. 5. 6. 7. This paper contains TWO sections. Section A is compulsory, and Answer any Two out of the Three questions in Section B. No written materials are allowed into the Examination Room. Write all your answers in the answer booklet provided. Do not forget to write your Registration Number. Do not write any answers on this question paper. Where appropriate draw large, clear and well labeled diagram in your answers 1 Section A : (Compulsory Questions) Attempt all of the following Short-answer and Definition Questions. (20 marks) 1. Which type of the diseases like Legionnaires, Influenza, Cholera and AIDS are the examples that fulfill the epidemiological status of infectious diseases? (3 marks) 2. In the characteristic pattern of the course of an epidemiologically qualified infectious diseases, what are the following periods called? (1 marks each) a) The period between the pathogen’s entry into the host’s body till the time of expression of the infection’s symptoms and signs. b) The period of the stage in which there is an onset of the signs and symptoms but not yet diagnosable c) The period in which the disease is in the phase of severe status and diagnosable d) The period with declining symptoms and signs or disappearing to be a recovery stage. 3. a) What are the different forms of disease types that the scope of epidemiological science has nowadays encompassed? (2 marks) b) How can one distinguish between an infection, a disease and health? (2 marks) 4. What are the four distinguishing properties of the African Histoplasmosis that differes from the usual Histoplasmosis? Which species is its causative agent ? (4 marks) 5. Distinguish between each of the following paired terminologies? (1 marks each) a) An endemic and sporadic disease. b) An epizootic and enzootic disease. c) Communicable and non-communicable diseases. d) Herd immunity and compromised immunity. e) Coagulase positive and catalase positive bacterial species. SECTION B : (Descriptive and Essay-type Questions) Attempt any Two of the following Three questions. (40 marks) 1. Write an essay to show all the detailed epidemiological features of the following fungal diseases : (20 marks) a) Histoplasmosis b) Cryptococcicosis c)Candidiosis 2. Using one example of the bacterial pathogens causing an epidemiological problem of either watery diarrhoeal disease or sexually transmitted disease, write an essay on its epidemiological features related to the following issues : (5 marks each) a) The causative agent of the disease you picked and the morphological, physilogical and pathogenesis features of this agent. b) The links of all the infectious cycle of that disease. c) The clinical and laboratory diagnosis and possible results. d) The treatment, control and preventive measures against that disease. 2 3. Which of the human body parts serve as the portal of entry of a pathogen as well as a physical, chemical, and biologcal barriers ? Write an essay on how each of these body parts perform all these mentioned activities. (20 marks) . END OF THE QUESTIONS and GOOD LUCK 3