- Biology of Blood and Marrow Transplantation
... obliterans (BO), immune cytopenias, and chronic immunodeficiency. The pathogenesis of chronic GVHD is poorly understood [1]. Symptoms usually present within 3 years after allogeneic HCT and are often preceded by a history of acute GVHD. Manifestations of chronic GVHD may be restricted to a single org ...
... obliterans (BO), immune cytopenias, and chronic immunodeficiency. The pathogenesis of chronic GVHD is poorly understood [1]. Symptoms usually present within 3 years after allogeneic HCT and are often preceded by a history of acute GVHD. Manifestations of chronic GVHD may be restricted to a single org ...
National Institutes of Health Consensus Development Project on
... obliterans (BO), immune cytopenias, and chronic immunodeficiency. The pathogenesis of chronic GVHD is poorly understood [1]. Symptoms usually present within 3 years after allogeneic HCT and are often preceded by a history of acute GVHD. Manifestations of chronic GVHD may be restricted to a single org ...
... obliterans (BO), immune cytopenias, and chronic immunodeficiency. The pathogenesis of chronic GVHD is poorly understood [1]. Symptoms usually present within 3 years after allogeneic HCT and are often preceded by a history of acute GVHD. Manifestations of chronic GVHD may be restricted to a single org ...
A review of the epidemiology of scrapie in sheep
... exposing healthy animals to infected stock, gave negative results (71, 74, 86). However, Parry demonstrated the autosomal recessive pattern of inheritance by investigating the occurrence of scrapie in commercial flocks (72). It has been suggested that there may have been considerable misclassificati ...
... exposing healthy animals to infected stock, gave negative results (71, 74, 86). However, Parry demonstrated the autosomal recessive pattern of inheritance by investigating the occurrence of scrapie in commercial flocks (72). It has been suggested that there may have been considerable misclassificati ...
Narrative Review: The Role of Th2 Immune Pathway Modulation in
... identified both frequent and severe exacerbations of asthma as hallmarks of severe disease. In addition, severe asthma is associated with comorbid conditions, such as obesity, hypertension, sinusitis, and type 2 diabetes (2, 5). This small subgroup of asthma drives most of the health care costs rela ...
... identified both frequent and severe exacerbations of asthma as hallmarks of severe disease. In addition, severe asthma is associated with comorbid conditions, such as obesity, hypertension, sinusitis, and type 2 diabetes (2, 5). This small subgroup of asthma drives most of the health care costs rela ...
Pneumococcal Septic Arthritis: Review of 190 Cases
... (20 of 108) among adults and 0% (0 of 82) in children. By univariate analysis (x2 test), mortality was predicted by pneumococcal bacteremia (mortality was 24% among patients with bacteremia [18 of 74 patients] and 6% among patients without bacteremia [2 of 31 patients] for whom adequate data were av ...
... (20 of 108) among adults and 0% (0 of 82) in children. By univariate analysis (x2 test), mortality was predicted by pneumococcal bacteremia (mortality was 24% among patients with bacteremia [18 of 74 patients] and 6% among patients without bacteremia [2 of 31 patients] for whom adequate data were av ...
... rather to attack its own cells and tissues. Such antibodies are called auto antibodies. It reacts with antigens to form immune complexes. Immune complex contained in the network can cause inflammation, tissue injury, and pain. Every patient has different symptoms as well as trigger factors dependin ...
Oxidative stress, innate immunity, and age
... restricting immune activation in response to these molecules [8]. The risk-associated CFHY402H mutation reduces the affinity of CFH to bind such molecules, thereby reducing its ability to maintain immune homeostasis in the eye. While wild-type CFH has demonstrated protective benefits in AMD, express ...
... restricting immune activation in response to these molecules [8]. The risk-associated CFHY402H mutation reduces the affinity of CFH to bind such molecules, thereby reducing its ability to maintain immune homeostasis in the eye. While wild-type CFH has demonstrated protective benefits in AMD, express ...
Pathophysiology - The Carter Center
... syndrome or condition that may not qualify to be called a disease. An alternate definition is "the study of the biological and physical manifestations of disease as they correlate with the underlying abnormalities and physiological disturbances. This lecture-note will provide a summarized basis for ...
... syndrome or condition that may not qualify to be called a disease. An alternate definition is "the study of the biological and physical manifestations of disease as they correlate with the underlying abnormalities and physiological disturbances. This lecture-note will provide a summarized basis for ...
Thrombocytopenia in neonates
... Infant's platelet count should be monitored if exposed to quinidine, penicillins, digoxin, and antiepileptic drugs; indomethacin, heparin-induced thrombocytopenia less common Management — If drug-associated thrombocytopenia is suspected, the offending agent should be withdrawn. – Transfusions sh ...
... Infant's platelet count should be monitored if exposed to quinidine, penicillins, digoxin, and antiepileptic drugs; indomethacin, heparin-induced thrombocytopenia less common Management — If drug-associated thrombocytopenia is suspected, the offending agent should be withdrawn. – Transfusions sh ...
Ankylosing spondylitis
_anagoria.JPG?width=300)
Ankylosing spondylitis (AS, from Greek ankylos, crooked; spondylos, vertebra; -itis, inflammation), previously known as Bekhterev's disease and Marie-Strümpell disease, is a chronic inflammatory disease of the axial skeleton, with variable involvement of peripheral joints and nonarticular structures. AS is one of the seronegative spondyloarthropathies and has a strong genetic predisposition. It mainly affects joints in the spine and the sacroiliac joint in the pelvis. In severe cases, complete fusion and rigidity of the spine can occur.""Bamboo spine"" develops when the outer fibers of the fibrous ring of the Intervertebral discs ossify, which results in the formation of marginal syndesmophytes between adjoining vertebrae.