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Characteristic #4 All living things reproduce using the same genetic mechanism (code) Each organism reproduces its own species Offspring inherit genetic instructions from their parents through a molecule called DNA Offspring can differ from their parents (genetic variation) Mitosis & Meiosis Mitosis and meiosis are processes of making new cells from old cells Both involve passing on genetic information from the old to the new cells Genetics is the study of the transfer of information at the level of the cell. Genetic information is found on DNA molecules within each cell nucleus DNA is divided into chromosomes Chromosomes are found in the nucleus of the cell Each organism has a different number of chromosome pairs (from one pair to hundreds of pairs) Humans have 23 pairs of chromosomes (see right) Chromosomes come in homologous (matching) pairs Homologous chromosomes are two chromosomes that have the same genes Chromosomes are divided into genes Genes control traits New Terminology Diploid: a body cell that has homologous pairs of chromosomes. Human diploid cells have 23 chromosome pairs (46 chromosomes). The picture above shows the chromosomes in a diploid cell. Autosome: body cells (every type of cell except for sex cells). All autosomes are diploid. Human autosomes have 46 chromosomes. Haploid: a sex cell that has only one set of chromosomes (one from each pair). Human haploid cells have 23 chromosomes. Gamete: sex cell (sperm, egg) that are haploid Mitosis & the Cell Cycle The cell cycle and mitosis are required for growth, repair, and replacement of cells. DNA passes from old to new cells during the cell cycle Before mitosis can begin, each parent cell must duplicates its DNA by making two copies of each chromosome After the DNA in the diploid cell is copied, the cell splits in half, with one copy of DNA in each of the two new diploid daughter cells Each new daughter cell is identical to the parent cell from which it was created Mitosis creates autosomes (body cells) How Does the Cell Cycle Work? Prior to division, the DNA relaxes in the nucleus. This is the Interphase stage Before dividing, each chromosome creates a copy of itself that remains attached to the original chromosome The copies thicken to form in an “X” shape After interphase, the nucleus of the cell divides in a series of four steps called mitosis o Prophase: Nucleus dissolves, and fibers attached to centrioles stretch across the cell o Metaphase: The chromosomes line up on the cell equator, and the fibers attach to them from both sides o Anaphase: The fibers shorten, splitting the chromosomes in half and pulling one half to each pole o Telophase: A new nucleus begins to form around each set of chromosomes, and the cell starts to split in half After mitosis, the cell splits into two daughter cells in a step called Cytokinesis o In animal cells, a cleavage furrow develops and the cell simply splits in two o In plants, a cell plate grows across the center of the cell, dividing it in half Summary o Mitosis is a way for cells to pass information to new autosomal cells within the same organism o The cell cycle & mitosis result in two diploid daughter cells that are identical to the original diploid parent cell o Cell cycle and Mitosis are important in growth, replacement, and repair of all body cells Meiosis Meiosis is the creation of gametes (sperm and eggs) to be used in sexual reproduction When the sperm fertilizes the egg, mom’s & dad’s DNA is combined together to produce a zygote (one-celled offspring) that will grow into a fetus, and then a baby To produce a baby with a normal # of chromosomes, each sperm and egg must have half the number of chromosomes Gametes (sex cells): Sperm and eggs that are found only in the testicles & ovaries. Gametes are haploid - they have 23 chromosomes (no pairs) and are formed through meiosis Differences between gametes and autosomes : o Gametes are sex cells - Autosomes are body cells o Gametes are only in the testicles and ovaries - Autosomes are found everywhere else in the body o Gametes are haploid - Autosomes are diploid o Gametes are made from meiosis - Autosomes are made from mitosis o Meiosis produces 4 different haploid gametes - Mitosis produces 2 identical diploid body cells How does Meiosis Work? The cell makes an extra copy of DNA as it does in the cell cycle Chromosomes “cross over” to exchange information before the first division. In crossing over, the homologous chromosomes get so close together that pieces of each chromosome actually swaps from one chromosome to the other. The cell divides two times. o During the first division, one of each homologous pair of chromosomes goes into each of the two cells (the pairs are separated from one another). o In the second division, the two copies of each chromosome are divided and end up in different cells At the end of meiosis, there are 4 haploid daughter cells The two chromosomes from each pair will end up in different daughter cells After meiosis, each daughter cell will have half as many chromosomes as the parent. After mitosis, the daughter cell will have the same number of chromosomes as the parent. Meiosis vs. Mitosis If the parent cell has 60 chromosomes, the 4 daughter cells will have 30 chromosomes each after meiosis If the parent cell has 60 chromosomes, the 2 daughter cells will also have 60 chromosomes each after meiosis Crossing Over Homologous chromosomes move very close together… so close that they sometimes they swap pieces. This creates brand new combinations of genes on each chromosome Crossing over leads to genetic variation – the offspring will have different traits than either of their parents Other Reproductive Issues Grab Bag of Knowledge Selective Breeding: selective breeding is when humans breed specific individuals with specific mates to exaggerate or produce certain traits. For example, dairy cows have been modified through selective breeding for large udders and high milk production. As a result, many cows have udders so large that they cannot walk without swinging their legs out to the side. Asexual reproduction is when one parent produces one or more identical offspring. No gametes or sex is involved, and there is no variation of traits. Examples of Asexual Reproduction: (1) A branch of a tree grows into a new tree when planted; (2) Hydra create offspring that grow from their body and then pinch off Sexual reproduction involves the fertilization of an egg by a sperm (two parents). Offspring are different from the parents and show genetic variation. Animal Life Cycles: some organisms such as plants and animals go through changes in form as they grow. Three types of life cycles are incomplete metamorphosis, complete metamorphosis, and alternation of generations. o Incomplete metamorphosis has 3 stages: egg, nymph, adult. Grasshoppers use incomplete metamorphosis. o Complete metamorphosis has 4 stages: egg, larvae (caterpillar), pupae (cocoon), adult. Complete metamorphosis is the life cycle that butterflies go through. o Alternation of Generations: Plants use alternation of generations because they alternate between a diploid and haploid life phase. This is the alternation of generations.