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Cells The basic structural and functional unit of all organisms. A cell is the smallest unit that can carry on all of the processes of life. Discovery of Cells: Scientists: Robert Hooke (1665) – used an early microscope to see cork cells. He coined the word “cells”. He mentioned that the cork cells reminded him of “a great many little boxes”. Anton van Leeuwenhoek (1673) – was the first to observe living cells. (algae) Discovery of Cells: More Scientists: Matthias Schleiden (1838) concluded that all plants were composed of cells. Theodor Schwann (1839) – concluded that all animals were composed of cells. Rudolf Virchow (1821 – 1902) – Observed that all cells come from other cells The Cell Theory: These scientists’ discoveries led to the Cell Theory: 1. All living organisms are composed of one or more cells. 2. Cells are the basic unit of structure and function in an organism. 3. Cells come only from the reproduction of existing cells. I. Introduction: A. Two types of cells: 1. Prokaryotes • Generally single celled organisms like bacteria. • Do NOT contain a nucleus or other membrane organelles. • Came about first • DNA is in an area called nucleoid 2. Eukaryotes • Single or multicellular organisms • Have nucleus and membrane bound organelles I. Introduction B. How many cells? • Some organisms are single cellular. • • Bacteria Some organisms are multicellular • 75 trillion cells in the human adult. C. How big are cells? • Different cells are different sizes. • Basically, cells are just large enough for their organelles • The average size is 10 microns I. Introduction Biggest reason for cell size: SURFACE TO VOLUME RATIO • In order for cells to survive, they must constantly exchange ions, gases, nutrients, and wastes with their environment. These exchanges take place at the cell’s surface. To perform this function efficiently, there must be an adequate ratio between the cell’s volume and its surface area. As a cell’s volume increases, its surface area increases, but at a decreased rate. If you continued to increase the cell’s volume, it would soon be unable to efficiently exchange materials and the cell would die. This is the reason that the kidney cell of an elephant is the same general size as a mouse kidney cell. I. Introduction D. Cell Shapes 1. Most cells are cubodial or spherical. 2. SHAPE DETERMINES THE FUNCTION • • • • Nerves Cells – elongated to reach out; receive and transmit impulses Epithelial Cells – thin and flattened to cover the body White Blood Cells – change shape to surround infectious disease cells Muscle cells – slender, rod-like to pull parts closer. Organelles The following organelles are in both prokaryotic and eukaryotic cells. II. Cell Membrane (also known as Plasma Membrane) A. Cell Membrane Function 1. Separates cell from its external environment 2. Gives cell its shape 3. Site of many metabolic reactions 4. Communication with other cells. II. Cell Membrane B. Cell Membrane Structure 1. Fluid Mosaic Model a. lipid bilayer acts as a liquid b. lipids and proteins change position c. many different pieces make it up: i. phospholipids ii. Proteins iii. Carbohydrates and lipids 2. Phospholipid bilayer a. makes up a majority of the membrane b. inside is hydrophobic (fatty acids) c. outside is hydrophilic (phosphate group) II. Cell Membrane B. Cell Membrane Structure 3. Proteins a. aid in communication b. form pores, gates or channels to allow molecules or ions to move in and out II. Cell Membrane B. Cell Membrane Structure 4. Carbohydrates a. bound to protein b. allows cells to recognize each other and communicate III. Cytosol & Cytoplasm A. Cytosol: • Jelly-like material inside the cell. • Surrounds organelles B. Cytoplasm: • All organelles and cytosol in the cell except nucleus and plasma membrane. • Is in constant motion (Cytoplasmic Streaming) IV. Ribosomes • Most numerous organelle • Site of proteins synthesis • Round, granular structures Last slide Organelles The following organelles are in eukaryotic cells… Both plant & animal cells. V. Endoplasmic Reticulum (ER) • Membrane network of folded & connected sacs and tunnels • Act as a transport system inside the cell. • Found in both plant & animal cells • Two Types 1. Rough ER: a. has ribosomes b. produces and transports proteins 2. Smooth ER: a. no ribosomes; b. absorbs fat c. metabolizes drugs VI. Golgi Apparatus 1. Flat stacks of membranes that are unconnected. 2. Modifies proteins from the ER by adding lipids and carbohydrates 3. Packages the modified protein 4. Secretes the proteins outside the cell. 5. Found in both plants & animal cells. VII. Mitochondria 1. Carries out cell aerobic respiration 2. Release energy from glucose 3. Makes Adenosine Triphosphate (ATP) • ATP provides energy for all cell reactions. i. Plants get glucose by making it themselves during photosynthesis. ii. Animals must eat plants or other animals to get glucose to make ATP 4. Large, elongated bean shape • Has 2 membranes an inner & outer • Inner membrane has many folds called cristae. i. These improve surface area to volume ratio for the cell respiration rxn’s that happen in the mitochondria. 5. Found in both plants & animals. VIII. Chloroplasts *Found in plant cells only! A. Football shaped structure B. Traps light energy from the sun and converts it to glucose during photosynthesis. C. Key Parts 1. Has 3 membranes: a. inner & outer like mitochondria. b. membrane around thylakoids. 2. Chlorophyll: green pigment that absorbs light energy. 3. Stroma: Fluid inside chloroplasts inner membrane. 4. Thylakoid: membrane sac 5. Grana: stack of thylakoids IX. More Plant Cell Only Structures 1. Cell Wall • Composed of cellulose • Supports and protects the plant 2. Central Vacuole • Large fluid filled structure • Contains: Enzymes, wastes (toxic), Water, ions, other nutrients • Provides pressure on the cell wall that keeps plants upright. X. Lysosomes & Vacuoles *Found in both plant & animal cells A. Lysosomes 1. Small, round organelles that contain digestive enzymes. 2. Digests food particles, bacteria trapped by white blood cells, and broken cell parts 3. Clean up and waste management B. Vacuoles 1. Saclike structures 2. store water, salts, and proteins 3. In animal cells it assists in endocytosis & exocytosis. 4. Plant cells have a large central vacuole. XI. Microtubules and Microfilaments A. Make up cytoskeleton: • Shape and support cell B. Move cellular material C. Make up centrosomes: • Found only in animal cells • Two hollow cylinders at right angles • Help distribute chromosomes during cell division. XII. Cilia and Flagella A. B. C. Function: Cell movement Structure: Both made of microtubules Differences 1. Cilia: a. Short, hair-likestructures b. ex.: Cells in nose & throat 2. Flagella: a. Long, whip-like structures b. ex. Sperm cells XIII. Nucleus A. Controls all cell activities B. Site where nucleic acids are made C. Parts of nucleus 1. Nuclear Envelope w/ pores: surrounds entire nucleus 2. Chromatin: Fine strands of DNA and protein (histones) 3. Chromosome: Strand of chromatin that coils up during cell division 4 . Nucleolus: Site where ribosomes are made Tissues Groups of cells that carry out a particular function XIV. Tissue Human tissue is organized into 4 categories: XV. Organ Systems A. Organs: Groups of tissue that perform a specific function B. Organ Systems: Groups of organs that perform a set of related tasks Remember from simplest to most complex level of organization: cells tissues organs organ systems organisms