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1 Genetics 3500 Fall 2014: In the tomato three genes are linked to the same chromosome. Tall is dominant to dwarf, skin that is smooth, is dominant to skin that is peachy, and fruit with a normal tomato shape is dominant to oblate. A plant that is true breeding for the dominant traits was crossed to a dwarf plant with peachy skin and oblate fruit. The F1 plants were then test-crossed to dwarf plants with peachy skin and oblate fruit. The following results were obtained. 155, tall smooth normal + + + 160 dwarf, peach ,oblate D P O 36 + + O 11 tall , peach oblate + P O 37 dwarf peach, normal D P + 12 dwarf, smooth normal d + + 1 dwarf smooth oblate D + O 2 tall peach normal + P + (a) (b) (c) (d) (e) (f) (g) tall smooth, oblate What indicates that the genes are linked? What was the genotype of the original heterozygous females? What is the order of the genes? What is the map distance between tall and smooth Between smooth and normal What is the coefficient of coincidence? Diagram the crosses in this experiment. 2 6 marks In cats , yellow coat color is determined by the b allele and black coat color is determined by the B allele. The heterozygous condition results in a condition known as tortoise shell. These genes are X linked. What kinds of offspring would be expected from a cross of a black male and a tortoise shell female. What are the chances of getting a tortoise shell male. 4 marks In mice, a series of five alleles determines fur color. In order of dominance, these alleles are: yellow fur but homozygous lethal; agouti with light belly; agouti (wild-type); black and tan; and a, black. For each of the following crosses, give the genotypes of the parents that generate these phenotypic ratios Parents A:light belly x yellow B; agouti x black and tan Offspring 1 yellow: 1 light belly 1 agouti: 1 black and tan 3 6 marks Summer squash plants with the dominant allele C bear white fruit, whereas plants homozygous for the recessive allele c bear colored fruit. When the fruit is colored, the dominant allele G causes it to be yellow; in the absence of this allele (that is, with genotype gg), the fruit color is green. What are the phenotypes and proportions expected from intercrossing the progeny of CC GG and cc gg plants (in otherword the F2 generation) ? Assume that the C and G genes assort independently. 6 marks ina puppy mill, multiple crosses were made between true-breeding lines of black and yellow Labrador retrievers. All the progeny were black. When these progeny were intercrossed, they produced puppies consisting of 91 black, 39 yellow, and 30 chocolate. (a) Propose an explanation for the inheritance of coat color in Labrador retrievers. (b) Propose a biochemical pathway for coat color determination and indicate how the relevant genes control coat coloration. 4 4 marks In fruitflies the genes b and r are separated by 16 map units. A fruitfly of genotype B R/b r is test crossed with b r/b r. What proportion of the progeny will be br/br? 4 marks A true breeding pea plant with round and green seeds was crossed to a true breeding plant with wrinkled and yellow seeds. The F1 were allowed to self fertilize. What percentage of the seeds are expect to be round and green? 5 marks A cross was made between a true breeding plant with blue flowers and purple seeds to a true breeding plant with white flowers and green seeds. The following data were obtained. F1 all progeny had blue flowers and purple seeds. Assume that there are two genes involved and that blue flowers and purple seed traits are dominant. What is the genetic explanation for this result? F2 generation : 103 blue flowers, purple seeds 40 blue flowers, green seeds 41white flowers. Purple seed 104 white flowers, green seeds.