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Objectives Observe what parts of the body are involved with breathing Hypothesize why the body responds the way it does when we breathe How do you breathe? AND WHY DO THOSE THINGS HAPPEN? What does breath affect? Nervous system Given what you know about blood flow and breathing, how are the circulatory and respiratory systems related? Respiration Involves both the respiratory and the circulatory systems Supply the body with O2 and dispose of CO2 Parts of the Respiratory System Nasal cavity Pharynx Larynx Trachea Bronchial tree Alveoli Nose Why do you have a nose? Passageway Warm and moisten air Filters Resonating chamber Contains olfactory receptors Nasal Cavity External nares (pair of opening) nostrils Internal nares (internal constriction) Act to reduce air flow to maximize efficiency and filtration Pharynx Passageway 3 divisions Nasopharynx: just air Uvula Oropharynx: air and food Laryngopharynx: food and air Larynx Point of divergence for air and food Air to trachea, food to esophagus Epiglottis Produces voice Larynx Trachea Sits atop esophagus Branches into bronchial tree Further branching descends into lungs Lungs Pleural cavities Lungs divided into lobes 3 on right, 2 on left Surfactant reduces the surface tension of fluid in the lungs and helps make the small air sacs in the lungs (alveoli) more stable. This keeps them from collapsing when an individual exhales. In preparation for breathing air, fetuses begin making surfactant while still in the womb. Babies that are born very prematurely often lack adequate surfactant and must receive surfactant replacement therapy immediately after birth in order to breathe. Alveoli End of bronchial branches Site of gas exchange Oxygen transport Can you remember?? Describe the path air takes as it moves from outside of your body to inside your lungs. Breathing Inspire/expire Largely regulated by pressure Intrapulmonary: Pressure inside lungs Atmospheric: Pressure outside lungs Breathing video Breathing Caused by changes in pressure Pressure moves from high concentration to low Inhalation: diaphram contracts, intercostal muscles contract Volume in thoracic cavity goes up, pressure goes down Atm. pressure> intraplural pressure= causes air to go in Exhalation Diaphram and intercostals relax Volume goes down, pressure goes up, air goes out Respiratory Volume Spirometer- will be using in lab Tidal volume: normal breathing ~0.5 L Inspiratory reserve: extra you can bring in ~3 L Expiratory reserve ~1 L Residual volume ~1.5 L Respiratory Capacity Inspiratory capacity: amount you can bring in Inspiratory reserve + tidal Functional residual capacity: amount typically in Expiratory reserve + residual volume Vital capacity: amount you can move Ir + tidal + er Total lung capacity: all volumes OPENER DAY 2 How do your diaphragm and intercostal muscles behave during an inhalation versus during an exhalation? How Gases Move in Blood Pressure moves from high to low Pressure of CO2 in alveoli = 40 mmHg(mm of mercury-unit of pressure) Pressure in capillaries = 45 mmHg Pressure of oxygen in alveoli = 104 mm Hg Pressure in capillaries = 40 mm Hg video Ventilation-Perfusion Coupling Control of Breath Rate Depth: how much air is brought in with each inhalation Rate: how frequently breaths are taken Affected by: Irritant reflexes Stretch receptors in lungs Hypothalamic controls Chemical controls Influences on Breath Rate and Depth Main influence: raising CO2 levels Hyperventilation Exercise Altitude Acclimation Disorders of Respiratory System COPD several causes Asthma: constrict respiratory apparatus Inhaler dilates Tuberculosis Bacterial infection Pnemonia: fluid buildup in lungs Lung cancer Usually die within 1 year of diagnosis 90% smokers OPENER What is the main thing that controls breath rate? What is the difference between tidal volume and vital capacity? What does the uvula do?