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International Children’s Heart Fund International Manual of Cardiothoracic Surgery A. Thomas Pezzella MD, Editor Founder/Director International Children’s Heart Fund www.ichfund.org www.imcts.org [email protected] Contact: A. Thomas Pezzella MD 17 Shamrock St. Worcester, MA 01605 USA e-mail – [email protected] cell phone – 1-774-272-0241 www.ichfund.org www.imcts.org Acknowledgements To Harold Jeghers MD who inspired a generation of physicians to employ an organized system of collecting and indexing textbook, monograph, and journal subjects/articles into a readily available Index Filing System (cf Appendix) To James I. Cox MD, the founder of the World Heart Foundation, for his vision and strategic planning in developing a model for bringing voluntary and humanitarian cardiothoracic surgery treatment, education, research, and services to a wider global population, as well as initiating the concept of open access to an internet based encyclopedia of cardiothoracic surgery. To Shanghai Chest Hospital, for the opportunity to spend one year (July 2005- July 2006) in Shanghai, China on behalf of the World Heart Foundation to help initiate a model 6 year cardiothoracic residency program. This experience gained the editor insights into the daily needs of the international audience of Cardiothoracic Surgeons. To Cho Ray hospital in HCM City, Vietnam, for also extending an invitation to implement a model 5 year CT surgery residency program from July, 2012 to January, 2013. International Handbook of Cardiothoracic Surgery Preface The source of current knowledge, information, and techniques in cardiothoracic surgery is derived from major textbooks, monographs related to specific areas or topics, journals, product information, corporate exhibits, product representatives/personal, the internet, the plethora of local, regional, national, and international meetings, congresses, conferences, symposia, seminars, workshops, and the emerging teleconference, telemedicine, teleconsult vehicles. This internet based open access text is primarily oriented to medical students, general surgery and CT surgery residents, physician assistants, and all others interested in a ready source of the practical basics of cardiothoracic surgery, including adult cardiac, pediatric cardiac, and general thoracic surgery. Hopefully the international character and focus of the information will be useful to a worldwide audience. It is offered free to those desiring it, and especially those without ready access to the published literature. It will be updated annually, or more frequently at the discursion of the contributing authors. No financial gain is planned or desired. Feel free to contact the author with questions, objections, suggestions, and a willingness to contribute to future editions. The ultimate goal is to provide the international cardiothoracic community with free access to practical information for everyday use in the active practice of the full spectrum of Cardiothoracic Surgery. A. Thomas Pezzella MD International Manual of Cardiothoracic Surgery Outline Ⅰ General Topics ·Introduction ·History of Cardiothoracic Surgery ·Global Aspects of Cardiothoracic Surgery ·Risk/Quality Assurance/Cost/Database/ Coding(USA) ·Complications/Errors ·Standards/Guidelines- STS/AHA/ACC ·Evidence Based Medicine ·Statistics/Research-Development/Grants/Funding/IRB ·Education/Training/Credentials/Licensure/ECFMG/ Job Opportunities – CV info. ·Ethics/Finance/ Billing/ Malpractice/ Reimbursement ·Government/Societies/Organizations ·Internet/Library resources/Publications/Computers/Library resources/Open access ·Administrative/Logistical considerations ·Corporate/Industry. ·Product ·Information ·Cost: Donation/Discounted/Market value ·Education ·Relationship guidelines .Contact information Ⅱ Basic Considerations ·Anatomy/embryology ·Physiology ·Biochemistry ·Pathology – Anatomical/Clinical ·Pharmacology ·Microbiology/Molecular Biology ·Pathophysiology ·Genetics ·Preventive Medicine/Public Health ·Clinical evaluation ·Etiological Considerations: Trauma, Infection, Cancer, Congenital, Post-operative sequellae, Iatrogenic, Local manifestations of systemic disease, Combinations-coexistence ·Flow sheets/ Case flow/ Protocols ·Algorithms ·Formulas Ⅲ Clinical Disciplines ·Cardiology – Clinical/Diagnostic/Invasive/Interventional/Nuclear/EPS ·Pulmonology – Pulmonary Function/Diagnostic/Endoscopy ·Oncology - Staging/ Chemotherapy ·Gastrointestinal/Endoscopy ·Hematology/Blood Bank ·Infectious Disease ·Immunology/Transplantation ·Neurology/ Psychological testing ·Psychiatry ·Pharmacology - Clinical ·Renal ·Endocrine/Metabolic ·Pediatrics ·Surgery, general surgery - specialties ·Intensivist (Pediatric ICU, Neonatal ICU, CCU, Medical ICU, Surgical ICU, CT Surgery ICU) ·Emergency Room / Trauma ·Anesthesia ·Pathology (Anatomic/Clinical) ·Radiology - diagnostic/invasive/interventional ·Radiotherapy ·Perfusion technology ·Nursing (ICU, OR, Ward, Clinic, Special care areas) ·BLS/ ACLS/ ATLS/ PCLS ·Allied health areas (Respiratory/Rehab./Lab./Occupational/Radiology) Ⅳ Patient Care ·Preventive/Public Health/Epidemiology ·Pre-operative – Indications/ Evaluation/ Diagnostic aspects/ Clinical pathways/ Risk ·Operative – Anesthesia/ Perfusion/ Nursing/ Logistics/ Equipment – Supplies/ Instruments/ OR design, systems ·Post-operative – Subsystem Approach (outline) ·Rehabilitation – Follow up care/ Residua/ Complications ·Results/ Outcomes Adult Cardiac Surgery ·Coronary Artery Disease (cf. outline) ·Valvular Heart Disease/ Endocarditis (outline) ·Aorta – Root/ Ascending/ Arch/ Descending/ Thoracoabdominal ·Trauma – Blunt/ Penetrating/ Blast/ Iatrogenic ·Transplantation – Heart/ Heart-Lung/ Assist/ Bridge ·Tumors ·Pericardium ·Arrhythmias – Medical/ Surgical/Pacing ·Tissue engineering/ Gene therapy/ Stem cell ·Cardiomyopathy/↓LV ·Vascular Surgery ·Complications General Thoracic (Adult/Pediatric) ·Preoperative/ Operative/ Postoperative considerations ·Trauma ·Cancer ·Infection ·Anatomical ·Chest wall ·Pleura ·Lung – Congenital/ Acquired/ Transplantation ·Tracheobronchial ·Thoracic spine ·Mediastinum ·Diaphragm ·Esophagus ·motor ·congenital ·trauma ·reflux ·cancer ·Complications Pediatric Cardiac Surgery ·Epidemiology – Incidence/ Prevalence/ Etiology ·Fetal/Neonatal Physiology/Pathophysiology ·Morphogenesis ·Anatomical tables/ charts ·Clinical cardiology (NICU, PICU, Ward, Clinic, ER) ·Diagnostic ·ECG ·ECHO- TTE, TEE ·CT ·MRI ·Catheterization- invasive ·Interventional Cardiology ·Database/ Classification/ Scores/ Risk ·Preoperative aspects ·Operative aspects ·Anesthesia: Access, Airway, Anesthesia, Monitoring, Drug support ·Perfusion, ECMO ·PICU – postoperative care ·Outcomes—complications, results ·Specific Congenital Anomalies ·Isolated/combined disorders ·Conduits – Conduit disorders ·PDA ·Vascular Rings ·Coarctation ·Pulmonic stenosis ·Interrupted Arch/Hypoplasia ·ASD; PAPVR; other Atrial Anomalies ·VSD ·AV Canal ·Truncus Arteriosus ·AP window ·RVOTO ·Tetralogy Fallot- with/ without pulmonary atresia ·Pulmonary Atresia/VSD ·Pulmonary Atresia/intact septum ·DORV ·DOLV ·Double Inlet Left Ventricle ·Double Inlet Right Ventricle ·Single Ventricle- physiology/ pathway ·TGA ·cTGA ·Ebstein anomaly ·LVOTO ·HLHS ·AV/LV tunnel ·Congenital MV problems ·Straddling/Overiding AV valve ·TAPVR/Pulmonary Vein Stenosis/Cor Triatriatum ·Anomalies of Systemic Venous Connections ·Coronary Artery Anomalies· ·Dextrocardia/situs inversus ·Isomerism/Heterotaxy ·Takayusu ·Kawasaki ·Rheumatic Fever/Rheumatic heart disease ·Tumors ·Trauma ·Pericardium ·Transplantation/Assist ·Endocarditis ·Arrhythmias/Pacemakers ·Adult congenital heart disease Appendices ·Index (Jegher’s) ·ABTS ·ECFMG ·websites ·Charts/Figures/Tables ·Formulas/ Equations ·Corporate contacts ·Pre-operative - orders ·Post-operative-orders ·Flowsheets ·Protocols ·Operative sheet ·Preference list (Pick List) ·Charting – ICU/Ward – Flow sheets ·Perfusion record ·Anesthesia record ·Resuscitation ·ACLS ·PALS ·ATLS ·Drugs- Anesthesia, cardiac, other ·Instruments – Basic – Adult Cardiac/Pediatric Cardiac/General Thoracic ·OR diagram ·ICU diagram ·Equipment/Supplies ·Medications ·Hospital Aspects – bricks/mortar; infrastructure ·Volunteer/ Humanitarian Efforts Cardiac Valve Surgery General Aspects · History ·Etiology ·Demographics · Valve anatomy/ dynamics ·Diagnostic modalities ·Surgical indications/ EBM/ Risk ACC-AHA Guidelines ·Statistical modalities/database Mitral Valve · Mechanical · Bioprosthetic · Leaflet/valve preservation techniques · Homograft ·Complications · Deac procedure ·Results/outcomes · Quattro Operative Techniques Approaches ·Median sternotomy ·Mini sternotomy ·Clam shell ·Left chest ·Right chest · RossⅡ · Repair - ring/band/other ·Annulus ·Leaflets ·Cords ·Papillary muscles ·Infective Endocarditis ·Minimally invasive ·Pediatric/Congenital (cf. congenital) ·Robotic technology ·Percutaneous, trans apical technology Aortic Valve / Ascending Aorta Tricuspid ·Mechanical ·Bioprosthetic ·AVR (mechanical) ·Repair - ring/band/other ·AVR (bioprosthetic) ·Ebstein’s anomaly ·AVR - Stentless ·Infective Endoacarditis ·Valve Sparring (David/Yacoub) ·Bental (mechanical) ·Bental (bioprosthetic) ·Freestyle ·Homograft x 3 (inclusion/cylinder/root) ·Small Aortic Root - techniques ·Pediatric/Congenital Pulmonary Valve ·Replacement ·Excision ·Repair ·Conduit- homograft/heterograft/ Dacron/Other ·Pediatric/Congenital Multiple Valve ·Ross ·Aortic/Mitral ·Ross/Konno ·Mitral/Tricuspid ·Modified Konno ·Aortic/Mitral/Tricuspid ·Large Ascending Aorta ·Konno/Rastan Valve Surgery/ Combinations ·AV repair ·Other cardiac procedures ·Apical Aortic Conduit ·Other non-cardiac procedures ·Ascending Aorta/Descending Aorta ·IHSS approaches ·Infective Endocarditis ·Pediatric/Congenital Subsystem Approach to Post-operative Care of the Adult Cardiac Surgery Point ·Hemodynamics - CO; arrhythmias; ischemia; failure; tamponade; IAB-Assist ·Respiratory - mechanical ventilation; tracheotomy; fast-track ·Hematological – Bleeding/Coagulopathy/Blood products/Conservation ·Neurological – Evaluation/ Stroke/ Seisure/Paraplegia ·Renal - Tests; acute, chronic failure ·Fluid/Electrolytes - Crystalloid/Colloid ·Infectious – prophylaxis; Immunology – Transplant -----------------·Wound - sternum; leg; arm ·Vascular - PVD ·GI – prophylaxis; complications ·Nutrition – Enteral/Parenteral ·Metabolic/Diabetes - Sliding scale insulin ·Medications/Fluids/Resuscitation/ Pharmacy/ Protocols ·Clinical Pharmacology ·Nursing Aspects – protocols/ infusion systems ·ICU – design/function Coronary Artery Disease - Coronary Anatomy/Physiology/Pathogenesis/Pathophysiology Acute/Chronic Coronary Diseases/Syndromes-Incidence/Prevalence/Risk Factors/Rehabilitation Diagnostic testing Medical treatment-Drugs/Coronary Care/Rehabilitation Invasive testing-coronary scores/Hemodynamics Interventional modalities-PTCA/ Stents/ Lytic Therapy/ IVUS CAD scores; Syntax TMR/ gene therapy/ stem cell/ tissue engineering Heart failure-approaches (coronary/ non-coronary) Surgery - History - Studies-Historic/Recent - Database/ QA/ Risk/ Comorbidity/ ACC-AHA Guidelines - Indications/Timing/Techniques - ONCAB/ OPCAB/ Minimally invasive - Spasm/bridge/intracavitary - Sequential/ aneurysms/ flows/ septal/ endarterectomy - Hybrid/Total Arterial grafting - Conduits/Leg/Arm/Other - Left main/elderly/young/females/other operations - Reoperation/ median sternotomy/ left chest - Mechanical-Shock/ MR /VSD LVA/ ↓LV/Rupture - Rehabilitation - Cost -Results- Early/Mid-term/ Long-term Basic Procedures/ Techniques/ Proficiency: Techniques NG tube insertion Foley bladder catheter IV access- peripheral/ central Chest tube insertion Peritoneal dialysis catheter insertion AVC fistula catheter insertion Umbilical arterial/venous catheter placement Broviac/ Hickman deep line placement ET intubation Gasrostomy/PEG/ Jejeunostomy Equipment Multiparameter monitor calibration, adjustments Mechanical ventilator CPAP IV infusion pumps CT suction Temporary pacemaker ECG, A-wire Defibrilater OPCAB suction devices ECHO—TEE. TTE IAB Oxymetry Somanetics monitor Ultrasound Proficiency ATLS/ ACLS/PALS Drug dosing Rowlatt Charts Formulas: hemodynamic/ pulmonary ECMO placement