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ABR-Scan Science Week 17 Unit for Antibiotics and Infection Control This ABR-Scan Science is compiled by the Unit for Antibiotics and Infection Control at the Public Health Agency of Sweden. It includes a summary of links to recent articles from a selection of 17 scientific journals that we find interesting. All journals included in the scan are listed at the bottom of the document. The articles are sorted according to our categorization: surveillance, treatment and diagnosis, prevention and intervention, microbiology and other. If you have any comments or suggestions, please send an e-mail to Karin Carlin at [email protected] Surveillance Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene. Eurosurveillance Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014. Eurosurveillance Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016. Eurosurveillance Risk factors for the acquisition of OXA-48-producing Enterobacteriaceae in a hospital outbreak setting: a matched case–control study. Journal of Antimicrobial Chemotherapy Plasmid-Mediated Colistin-Resistant Escherichia coli in Bacteremia in Switzerland. Clinical Infectious Diseases Neisseria gonorrhoeae Resistant to Ceftriaxone and Cefixime, Argentina. Emerging Infectious Diseases Shigella Antimicrobial Drug Resistance Mechanisms, 2004–2014. Emerging Infectious Diseases Bloodstream infection caused by extensively drug-resistant Acinetobacter baumannii in cancer patients: high mortality associated with delayed treatment rather than with the degree of neutropenia. Clinical Microbiology and Infection The worldwide spread of ciprofloxacin-resistant Shigella sonnei among HIV-infected men who have sex with men, Taiwan. Clinical Microbiology and Infection Solna Folkhälsomyndigheten, SE-171 82 Solna. Visit: Nobels väg 18. Östersund Folkhälsomyndigheten, SE-831 40 Östersund. Visit: Forskarens väg 3. Telephone + 46 10 205 20 00 E-mail [email protected] www.folkhalsomyndigheten.se Page 2 (3) Epidemiological Markers for Interactions Among Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Upper Respiratory Tract Carriage. Journal of Infectious Diseases Carbapenem- and Colistin-Resistant Enterobacter cloacae from Delta, Colorado, in 2015. Antimicrobial Agents and Chemotherapy Treatment and diagnosis Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study. Lancet Infectious Diseases Studying ceftazidime-avibactam in selected populations. Comment. Lancet Infectious Diseases Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance. Journal of Antimicrobial Chemotherapy Shiga Toxin–Producing Escherichia coli Infection, Antibiotics, and Risk of Developing Hemolytic Uremic Syndrome: A Meta-analysis. Clinical Infectious Diseases Time Is of the Essence: The Impact of Delayed Antibiotic Therapy on Patient Outcomes in Hospital-Onset Enterococcal Bloodstream Infections. Clinical Infectious Diseases Optimizing the Clinical Use of Vancomycin. Antimicrobial Agents and Chemotherapy Prevention and intervention Reducing Unnecessary Antibiotic Prescriptions. JAMA Executive Summary: Implementing an Antibiotic Stewardship Program: Guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clinical Infectious Diseases A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit. Clinical Infectious Diseases Effect of vaccination programmes on mortality burden among children and young adults in the Netherlands during the 20th century: a historical analysis. Clinical Infectious Diseases Solna Folkhälsomyndigheten, SE-171 82 Solna. Visit: Nobels väg 18. Östersund Folkhälsomyndigheten, SE-831 40 Östersund. Visit: Forskarens väg 3. Telephone + 46 10 205 20 00 E-mail [email protected] www.folkhalsomyndigheten.se Page 3 (3) Microbiology In vitro pharmacokinetics/pharmacodynamics of the combination of avibactam and aztreonam against MDR organisms. Journal of Antimicrobial Chemotherapy Real-time PCR for detection of plasmid-mediated polymyxin resistance (mcr-1) from cultured bacteria and stools. Journal of Antimicrobial Chemotherapy Next-Generation Sequencing of Mycobacterium tuberculosis. Emerging Infectious Diseases High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus. Emerging Infectious Diseases Rapid Detection of Polymyxin Resistance in Enterobacteriaceae. Emerging Infectious Diseases Acquisition of Broad-Spectrum Cephalosporin Resistance Leading to Colistin Resistance in Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy Other Tackling antimicrobial resistance in France. Lancet Phagocytosis and Killing of Carbapenem-Resistant ST258 Klebsiella pneumoniae by Human Neutrophils. Journal of Infectious Diseases Protective Effect of a Synbiotic against Multidrug-Resistant Acinetobacter baumannii in a Murine Infection Model. Antimicrobial Agents and Chemotherapy The publications included in the scan are: Antimicrobial Agents and Chemotherapy, British Medical Journal, Clinical Infectious Diseases, Clinical Microbiology and Infection, Emerging Infectious Diseases, Eurosurveillance, Infection Control & Hospital Epidemiology, Infectious Diseases, JAMA - The Journal of the American Medical Association, Journal of Antimicrobial Chemotherapy, Journal of Hospital Infection, Journal of Infectious Diseases, Lancet, Lancet Infectious Diseases, New England Journal of Medicine, Pediatrics and Scandinavian Journal of Primary Health Care. In addition, other articles from other publications can be included. Solna Folkhälsomyndigheten, SE-171 82 Solna. Visit: Nobels väg 18. Östersund Folkhälsomyndigheten, SE-831 40 Östersund. Visit: Forskarens väg 3. Telephone + 46 10 205 20 00 E-mail [email protected] www.folkhalsomyndigheten.se