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Basic Ultrasound Physics Tavakoli. M.B, Isfahan University of Medical Sciences, School of Medicine Department of Medical Physics and Medical Engineering 1 Main topics • • • • • • • • • • • • • 2 Basic Physics Mechanical Phenomena Sound wave Spectrum Velocity of sound Transmission through a barrier Attenuation Production and detection Ultrasonic field in front of a transducer Resolution Ultrasonic systems Clinical Uses Biological effects Basic Ultrasound Physics continue • Sound Wave: Is a type of mechanical energy that is transmitted through medium. • Propagation: Sound wave propagate through deformation of the elastic medium • Sound wave spectrum: Is divided into three region of Inferasound (f<20Hz); Sound (f=20 to 20000Hz) and Ultrasound (f>20kHz) • Wave equation: A=A0sin (ωt+θ) A=amplitude; A0=Maximum amplitude; θ=initial phase and ω =2пf f=1/T 3 4 Basic Ultrasound Physics continue • Types of sound wave: • Longitudinal • Shear wave • Compressibility: The fractional decrease in volume when pressure applied to the material. • B=Bulk modulus=-stress/strain • The reciprocal of compressibility is bulk modulus • B(bulk modulus)=1/ K (compressibility of medium) 5 Sound velocity • Sound velocity • c(m./sec)=f(1/sec or Hz)λ(m) • Sound velocity depends on compressibility (K) • c=1/(Kρ)1/2=(B/ ρ)1/2 In materials with higher compressibility velocity of sound is less and Vic versa 6 Propagation velocity = C C B 1 K B = modulus of elasticity ρ = density of rest K=Comperesibility C =λf 7 Acoustic Impedance Z is the acoustic impedance Acoustic Pressure: P=Zv It can be show that B Z Z C .B C 8 Reflection • According to Snell laws • 1-Incident and reflected angles are equal αi = α r • 2-the relation between incident and transmission angles is: Sinαi/ Sinαt=ci/ct • 3-All of the incident reflection and transmitted rays are in the same plane Z cos i Z1 cos t I A R r ( r ) 2 2 Ii At Z 2 cos i Z1 cos t • Energy transmission and reflection percentages are: T 9 2 It A 4Z1Z 2 cos i cos t ( t )2 Ii Ai Z 2 cos i Z1 cos t 2 For specular reflection: Amplitude reflection coefficient r : r I r Pr Z 2 Z1 I i Pi Z 2 Z1 Energy transmitted and reflection coefficient t : • T It 1 R2 Ii 4Z1Z 2 Z 2 Z1 2 Pt Z 2Z 2 t 2 1 R Pi Z1 Z 2 Z1 10 The continuity condition is: R+T=1 Typical values for diagnostic ultrasound: Ultrasound f > 20KHz f : 1 to 10 MHz λ : 1.5 to 0.15 mm in muscle J (Acoustic Intensity)< 100 mW 2 cm Acoustic Pressure P<0.57 bar Particle velocity v<3.5 cm/s Elongation ξ < 2*10-6 11 Particle acceleration < 7*104 g usually 1 to 10 mW cm2 Physical effects Reflection Refraction Diffraction Scatter Absorption 12 Attenuation • Intensity(Watt/cm2) 13 The special unit for these coefficient is the Neper (NP) per centimeter. The attenuation coefficient at 1 MHZ for various tissue types are different. Level (db)= 10 log ( AMax )2 ( I max ) A Level (db)= 20 I A log ( Max ) 10log( I max ) A I dB=8.868np Ultrasound production and detection • Use pizoelectric • Natural-Quartz • Artificial-PVDF, PZT… 16 - crystal with coated electrodes on each side - Backing material - Matching layer - Housing and insulator - Ground electrode - Connector - Resolution Near field: D2 F D2 a2 NFD 4C 4 Far field: 1.22 1.22c Sin 0.61 a D Df Actual intensity distribution - Focused transducer with an acoustic lens. - Focused transducer with a curved piezoelectric. • Side lobes are secondary projections of ultrasonic energy that radiate away from the main ultrasound beam. • The intensity of side lobes is normally 60 to 100 dB below that of the main ultrasound beam, which usually does not pose significant problems. Ultrasonic technique Pulse echo Real time A-scan B-scan M-mode Doppler 22 A-scan Main part Clock pulse repetition frequency (PRF) Ultrasonic velocity Depth of investigation Number of line per image Filter Transmitter Receiver TGC+Amplifier Radio Amp. Video Amp. Time generator Processing B-scan One dimension Two dimension 24 Commercial system Mechanical Linear Sector Electrical Linear Sector 25 Mechanical sector scanner Advantages Simple Cheap Acceptable resolution Disadvantage Noise Mechanical fracture Reverberation Sector field 26 Electronic Scanners Linear Typical values: Number of elements 60-120 Elements width (b) 1-4 λ Frequency 3.5-7MHz Length of ceramic (L) 2-11.5 cm Scanning length (image width) 2-10 cm 27 Sector 28 Electronic focusing M-Mode ioo • 29 nbbnnb • 30 Doppler ultrasound jdffgg • 31 Velocity determination 2vf fD cos C Optimum frequency for doppler is f0=90/R R = soft tissue distance from target Suitable frequency=2 MHz for deep 5-7 MHz for superficial Doppler examination continues wave 32 pulse wave Color flow imaging Duplex scanners spectral Analysis Power spectrum 33 Doppler systems 34 Ultrasonic probes tkyk • 35 Clinical application • Cardiology Shortcut to Doppler_mitral_valve.lnk 36 Endocarinology • 37 Gasteroenterology ghjhgjgj • 38 Obstetric and Gynaechology bdzz • 39 Urology hkhh • 40 Ophtalemology Malignant melanoma of the iris at pupil margin. Pigmented lesion of the iris in the region of the angle demonstrating extension to the ciliary body. Ciliary body melanoma. 41 sdfs • Quality controls (Q.A) Axial resolution Lateral resolution Penetration depth and sensitivity Dynamic range Accuracy Hand copy performance 42 Biological effects • 1-Thermal • 2-Mecanical • 3-Cavitation 43 Biological effects 44 The Ear • • • • • • • • • • • • • • 45 Structure External ear Canal length=2.4cm Tympanic membrane diameter=7mm Thickness=0.1mm Vibration amplitude=a few A Middle ear Three small bones: of malleus, incus, stepes and oval window Amplification by the bones=1.5 by the membrane area=20 Internal ear Three semicircular canal for balance Chochlea Prelymph, Vestibular chamber and endolymph Hearing level and ear sensitivity 46 • • • • • Threshold of hearing=10-12W/m2 Hearing level is determined by dB Ear sensitivity depend on frequency Max sensitivity is about 2-3kHz Resonant frequency of ear canal 3300Hz • • • • • • Resonant frequency of middle ear 700-1500Hz High frequency is sensed by initial portion of inner ear Low frequency is sensed by end portion Resolution of ear is very high (about 3Hz) Ear can differentiate different sound level Ear can determined source position • Hearing loss • 1-Conduction loss • Can be treated • 2-nerve loss • Can not be treated Audiometry • Determination of threshold of hearing level 47 High frequency electricity • Mainly used in therapy • Biological effects • The main effective factors are frequency and current 48 Types of current • AC current • DC current • Production of AC current 49 Types of AC current • • • • 50 1-Contineus damping ac current 2-Noncountinous damping ac current 3-Non-countineous current 4-Countineous current Heat production • 1-Capacitor applicator • 2-Coil applicator • 3-Shortwave (10 to 100MHz) • 4-Microwave (2450 and 4329.2MHz) 51 Types of capacitor applicators • 1-conterplannar (chest) • 2-Co-plannar (vertebra column) • 3-Crossfire (sinus) • 4-Monopolar (Mostly for surgery) 52 Physiological effects of high frequency currents • • • • • • 53 1-Increase blood flow 2-Increase metabolism 3-Effect of nervous stimulation 4-Effects of muscle 5-Reduce blood pressure 7-Increase endocrine Diathermy • Use of electric current to increase temperature • The frequency used (10-100MHz and mainly 27MHz • The effects are: • Stimulation with less than 0.01s period can not be sensed=> f above 100KHz can not make shock 54 Forbidden case for diathermy • • • • • • 55 1-bleeding 2-therombosis 3-pregnancy 4-inability to sense temperature 5-Tumers and radiotherapy 6-Mental impaired Electric surgery (electrocuthery) • 1-Coagulation • 2-Vaporization • 3-Discication 56 Types of electrodes • Usually needs two electrodes of active and null or inactive • Active types: • Inactive types 57 58