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1 COLLEGE OF MEDICINE GIT - 323 BLOCK Intended Learning Outcomes (ILO’s) 1435 [2014] 2 GIT 323 Block Educational Framework (Week 1) The intended learning outcomes 123456- Teaching and learning method Enlist the structures forming oral cavity. Enumerate the types and arrangement of teeth. Discuss the structure of teeth. Explain the structure of tongue. Describe the muscles of tongue. Enumerate the structures present in the roof and floor of mouth. Anatomy Lecture Anatomy Lab SDL 1- Types of food we take, carbohydrate, fat & protein their end products for digestion 2- Four basic processes of digestion- motility, secretion, digestion and absorption 3- Functional Anatomy of digestive system 4- Accessory glands salivary, pancreas, liver Physiology lecture SDL 1234567- Enlist the salivary glands. Define their location. Discuss the parotid gland. Where does the parotid duct open . Describe the submandibular and sublingual glands. Where does the ducts of submandibular and sublingual glands open. Know the important relations of salivary glands. Anatomy Lecture SDL 1- Understanding the definitions and utilization of dietary reference standards (DRIs). 2- Explaining the concepts of energy balance in human body. 3- Recalling the food sources and contents of energy. 4- Recognizing the ways of energy expenditure in human body. Biochemistry 5- Understanding the concepts of acceptable macronutrient distribution ranges Lecture (AMDRs). 6- Understanding the general concepts of the biological effects of macronutrients in SDL health and disease. 7- Understanding the concepts of the role of micronutrients including vitamins and minerals in maintain normal metabolism in human body. 8- Recognizing the biochemical explanation of clinical manifestations of deficiency Assessment strategy MCQs SAQs OSPE MCQs SAQs MCQs SAQs OSPE MCQs SAQs Remarks for achievement of ILO’s yes no 3 and excessive intakes of micronutrients. - 1- Define Pharynx. 2- Describe its different parts. 3- Why its anterior wall is deficient . 4- Discuss the pharyngeal muscles. 5- Give its blood supply and venous drainage. 6- Discuss its sensory and motor nerve supply. Name of the glands contributing to the saliva secretion and their % of contribution Enlist thecomposition, and functions of saliva Process of regulation of saliva secretion Xerostomia Anatomy Lecture SDL Physiology lecture MCQs SAQs OSPE MCQs SAQs MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning 4 GIT 323 Block Educational Framework (Week 2) The intended learning outcomes 12345- 123- 1- Define esophagus. 2- Enlist relations of esophagus. 3- Describe the constrictions of the esophagus . 4- Give its blood and nerve supply. 1- Identify the results of folding. 2- Identify the derivatives of the hindgut. 3- Describe the development of the hindgut. 4- Identify the congenital anomalies of the hindgut. Enumerate the composition of gastric secretion Control or regulation of gastric secretion (neural & hormonal) Functions, digestion and absorption in stomach Why acidic pH in stomach does not damage the gastric mucosa Peptic ulcer 1- Define the abdominal wall. 2- Enlist the layers. 3- Give its blood and nerve supply. 4- Applied anatomy 5- Discuss stomach in terms of its parts and musculature. 6- Enlist the peritoneal relations of the stomach . 7- Enlist the structures forming stomach bed. 8- Discuss the blood supply of the stomach. Gastric motility - Filling storage, mixing and emptying of stomach Chyme formation Factors affecting the motility – role of secretin and CCK Teaching and learning method Assessment strategy Anatomy Lecture Anatomy Lab SDL MCQs SAQs OSPE Embryology Lecture SDL MCQs SAQs OSPE Physiology Lecture SDL Anatomy Lecture Anatomy Lab SDL Physiology Lecture SDL MCQs SAQs MCQs SAQs OSPE MCQs SAQs Remarks for achievement of ILO’s yes no 5 123412345- Understanding definition of GERD. Discussing the Pathophysiology of GERD. Listing the clinical manifestations of GERD. Listing the complications of GERD specially Barrett's esophagus. Recognizing the typical clinical presentation and risk factors for peptic ulcer disease. Understanding pathophysiology of PUD focusing on H. pylori. Identifying the gross and microscopic picture of peptic ulcer. Identifying the complications of PUD. Recognize the microbiological properties, virulence, pathogenesis, type of infection, and the diagnostic procedure of Helicobacter pylori. Pathology Lecture SDL Pathology Lecture Microbiology Lecture MCQs SAQs MCQs SAQs OSPE MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning 6 GIT 323 Block Educational Framework (Week 3) The intended learning outcomes 1- Define Peritoneum. 2- Enumerate its functions. 3- Explain the general organization of the peritoneum. 4- Distinguish between Intraperitoneal and Retroperitoneal Structures. 5- Describe Peritoneal Ligaments. 6- Define lesser and greater omenta. 7- Understand the location of epiploic foramen . 8- Discuss mesentery and mesocolon. 9- Explain the Peritoneal sacs. 1- Identify the results of folding. 2- Identify the derivatives of the foregut. 3- Describe the development of the esophagus. 4- Describe the development of the stomach. 5- Identify the congenital anomalies of the esophagus and stomach. 1- Identify location of the Pancreas 2- Recognize important anatomical relations to the pancreas 3- Identify different parts of the pancreas 4- Recognize main and accessory pancreatic ducts 5- Identify blood supply of the pancreas 6- Discuss lymphatic drainage, and nerve supply of the pancreas 1- List the parts of the gastrointestinal tract and associated glands 2- Describe the general histological features of the gastrointestinal tract 3- Identify tongue papillae and describe their structures. 4- List the location of the taste buds & Describe the structure of the taste bud 5- Describe the histological features of the various salivary glands Teaching and learning method Anatomy Lecture Anatomy Lab SDL Embryolog Lecture Anatomy Lab SDL Anatomy Lecture Anatomy Lab SDL Histology Lecture SDL Assessment strategy MCQs SAQs OSPE MCQs SAQs OSPE MCQs SAQs OSPE MCQs SAQs OSPE Remarks for achievement of ILO’s yes no 7 1234- Exocrine function of pancreas Pancreatic secretion – composition, regulation, functions Effect of secretin and CCK hormone on pancreatic secretion Role of enzymes present in pancreatic secretion in food digestion • • Identifying different types of pancreatitis. Listing various causes of pancreatitis as biliary stone, alcohol and the mechanism of their action. Understanding how to diagnose a case of pancreatitis by the help of clinical presentation, histopathologic changes and imaging studies and differentiating it from other causes of acute abdomen. Know the serious complications of pancreatitis. • • 12345671- Describe the surface anatomy of the duodenum. Enumerate parts of the duodenum. Discuss anatomical relations of the duodenum. What structures open in the second part of the duodenum. Explain the blood supply of the duodenum. Define celiac trunk. Enumerate the branches of celiac trunk. Describe the mechanism of action, therapeutic uses, pharmacokinetic, contraindications and adverse effects of antiulcer drugs. Physiology Lecture SDL Pathology Lecture Anatomy Lecture Anatomy Lab SDL Pharmacology Lecture MCQs SAQs MCQs SAQs OSPE MCQs SAQs OSPE MCQs SAQs MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning 8 GIT 323 Block Educational Framework (Week 4) The intended learning outcomes 1234- 1- Identify location of the liver. 2- Recognize important anatomical relations of the liver. 3- Identify different lobes of the liver. 4- Discus the biliary tract. 5- Identify blood supply and venous drainage of the liver. 6- Discuss lymphatic drainage of the liver. 7- Discus innervation of the liver. 1- Identify the results of folding. 2- Identify the derivatives of the midgut. 3- Describe the development of the midgut. 4- Identify the congenital anomalies of the midgut. Functions of liver Bile secretion, composition Role of bile in in fat emulsification and digestion Entero hepatic circulation of bile 1- Describe the histological features of the esophagus 2- Identify the muscular wall structure of the esophagus 3- Describe the histological features of the stomach. 4- Describe the gastric gland 5- List the type of the cells comprising the gastric gland and their functions 1- Jaundice – Hemolytic, Hepatic and Obstructive 2- Gall stones 3- Source of bilirubin, its excretion Teaching and learning method Anatomy Lecture Anatomy Lab SDL Embryology Lecture SDL Physiology Lecture SDL Histology Lecture Histology Lab. SDL Physiology Lecture SDL Assessment strategy MCQs SAQs OSPE MCQs SAQs MCQs SAQs MCQs SAQs OSPE MCQs SAQs Remarks for achievement of ILO’s yes no 9 1- Understanding the normal Liver functions and predicting what is the clinical picture when liver failure occur. 2- Recognizing definition of hepatitis and discussing its types (Acute, Chronic, and Fulminant). 3- Listing different causes and patterns of hepatitis. Pathology Lecture 4- Understanding the differences between different types of hepatotropic SDL viruses regarding type of nucleic acid, method of Transmisson, Carrier state, Chronicity. 5- Listing the cellular changes in both acute and chronic Hepatitis. 123456- Discuss anatomical structure of small intestine. Enlist the characteristic features of small intestine. Identify blood supply and venous drainage of the small intestine. Discuss lymphatic drainage of the small intestine. Discus innervation of the small intestine. Identify the branches of the superior mesenteric artery. Anatomy Lecture Anatomy Lab SDL MCQs SAQs OSPE MCQs SAQs MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning 10 GIT 323 Block Educational Framework (Week 5) The intended learning outcomes 12345612- 3456- Discuss anatomical structure of large intestine. Enlist the characteristic features of large intestine. What are the different positions of the Appendix. Identify blood supply and venous drainage of the large intestine. Discuss lymphatic drainage of the large l intestine. Discus innervation of the large l intestine. Compare the histological features of the small and large intestines. Identify the histological features of different transitional areas in the gastrointestinal tract (gastro-esophageal, gastro-duodenal, ilio-ceacal and recto-anal). Compare between the histological features of the major salivary glands Describe the histology of the liver Describe the histology of the biliary system. Describe the Histology of the pancreas. Teaching and learning method Anatomy Lecture Anatomy Lab SDL Histology Lecture Histology Lab SDL 1- Understand the overall process of dietary protein and carbohydrates digestion, the organs involved, the enzymes required, and the end products. Biochemistry Lecture 2- Recognizing the biochemical explanation for the clinical manifestations of diseases that involve defective protein or carbohydrates digestion and/or SDL absorption. Recognize Hepatitis A, B, and C considering classification, port of entry, virulence Microbiology Lecture factors, pathogenesis and clinical presentation, and diagnostic procedure. 1- Identify the derivatives of the midgut. 2- Describe the development of the midgut. 3- Identify the congenital anomalies of the midgut. 1- Mechanisms of intestinal Motility, Secretin, Digestion, Absorption, 2- Factors affecting intestinal motility, & secretion Embryology Lecture Physiology Lecture Physiology Tutorial Assessment strategy MCQs SAQs OSPE MCQs SAQs OSPE MCQ SAQs MCQs SAQs MCQs SAQs OSPE MCQs SAQs Remarks for achievement of ILO’s yes no 11 SDL 12 1- Understand the overall process of dietary lipids digestion, the organs involved, the enzymes required, and the end products. Biochemistry Lecture 2- Recognizing the biochemical explanation for the clinical manifestations of diseases that involve defective lipids digestion and/or absorption. (maldigestion SDL and malabsorption syndrome). 1- Pathology Understanding mechanism of Bilirubin formation and how its increase can lead to jaundice. 2- Discussing Pathophysiologic classification of Jaundice and clinical characteristics of each type. Pathology lecture MCQs SAQs MCQs SAQs MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning 13 GIT 323 Block Educational Framework (Week 6) The intended learning outcomes 123456- Discuss the anatomical structure of the rectum. Describe the anatomical structure of the anal canal. Identify blood supply and venous drainage of rectum and anal canal. Discuss lymphatic drainage of rectum and anal canal. Discus innervation of rectum and anal canal. Define external and internal hemorrhoids. 12345- Identify the causative agents of invasive Gastroenteritis, the pathogenesis, the virulence factors, and their toxicity and diagnostic procedures. Motility Secretion Absorption Feces Defecation reflex 1- Understanding definition of malabsorption. 2- Discussing causes and mechanism of malabsorption. 3- Listing the commonest diseases associated with malabsorption such as celiac sprue, whipple disease, Short Bowel Syndrome and tropical sprue. Teaching and learning method Anatomy Lecture Anatomy Lab SDL Microbiology lecture SDL Physiology lecture SDL Pathology lecture SDL 1- Understanding the biochemical aspects of fatty acid oxidation and ketone bodies synthesis taking place in the liver cells. 2- Recognizing the biochemical impacts of defects of fatty acid oxidation on Biochemistry Lecture clinical manifestations. SDL 3- Explaining the causes of overproduction of ketone bodies in the liver with reference to clinical consequences of ketonemia especially in diabetic ketoacidosis. Assessment strategy MCQs SAQs OSPE MCQs SAQs MCQs SAQs MCQs SAQs MCQs SAQs Remarks for achievement of ILO’s yes no 14 1- Identifying in brief the major form for the disposal of amino groups derived from amino acids Biochemistry Lecture 2- Understand the importance of conversion of ammonia into urea by the liver 3- Recalling the reactions of urea cycle. SDL 4- Identify the causes and manifestations of hereditary and acquired hyperammonemia. 1- Explain the pharmacological profile of antiemetic and pro kinetic Pharmacology lecture agents SDL MCQs SAQs OSPE MCQs SAQs MCQs: Multiple choice questions; SAQs: Short answer questions OSPE: Objective structured practical examination; SDL: Self Directed Learning 15 GIT 323 Block Educational Framework (Week 7) The intended learning outcomes 1- Recalling general liver functions. 2- Understanding the biochemical aspects of normal billirubin metabolism with its implications on clinical aspects of laboratory diagnosis of jaundice. 3- Recognizing laboratory investigations used to assess the liver functions. 4- Interpretation results of liver function tests in diagnosing different liver disease. 1- Understanding definition of IBD 2- Discussing the etiology of IBD. 3- Recognizing the commonest two types of IBD (Crohn’s disease, ulcerative colitis). 4- Understanding the pathological features of ulcerative colitis. 5- Understanding the pathological features of crohn's disease. 1- Enumerate three major hormones of GIT a. Gastrin b. Secretin c. Cholecystokinin 2- + Other Hormones 3- Motilin - Intestinal Motility 4- GIP – Stimulate Insulin secretion 5- VIP – Increases intestinal secretion Correlate the pathogenesis of Vibrio cholera, and Brucella with the Assessment strategy Biochemistry Lecture SDL MCQs SAQs OSPE Pathology Lecture SDL MCQs SAQs OSPE Physiology Lecture SDL Enlist the causative agents of non-invasive enteritis, Malta fever, and food poisoning. Teaching and learning method Microbiology Lecture SDL MCQs SAQs MCQs SAQs OSPE mechanism of action of microbial virulence factors. 1- Understand and discuss the pharmacology of drugs used as laxative and anti-diarrheal MCQs Pharmacology Lecture SAQs SDL Remarks for achievement of ILO’s yes no 16 MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning GIT 323 Block Educational Framework (Week 8) The intended learning outcomes 1-Enlist the parasitic and viral causative agents of enteritis. 2-Differentiate between parasitic and viral causative agents of enteritis according to microbiological aspects. 1- Recognize the pharmacological agents for the treatment of inflammatory bowel disease Teaching and learning method Microbiology Lecture Microbiology Tutorial SDL Assessment strategy Remarks for achievement of ILO’s yes no MCQs SAQs MCQs Pharmacology Lecture SAQs SDL MCQs: Multiple choice questions; SAQs: Short answer questions; OSPE: Objective structured practical examination; SDL: Self Directed Learning