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5/5/15 The Cardiovascular System Chapter 14 The Cardiovascular System When you h ave completed this chapter should be able to: • 1. Describe the external and internal anatomy of the heart. • 2. Follow the flow of blood through the heart, pulmonary circulation, and systemic circulation. • 3. Explain how the heart valves keep blood flowing in the proper direction through the heart. 1 5/5/15 The Cardiovascular System • 4. Describe the components of the cardiac conduction system and explain how it works to keep the heart beating in an organized fashion. • 5. Explain what happens during one cardiac cycle. • 6. Understand cardiac output and what conditions can affect it. • 7. Describe the anatomy of arteries, veins, and capillaries and understand the function of each type of blood vessel The Cardiovascular System • 8. Understand the difference between fetal and newborn circulation. • 9. Understand the different m ethods used to evaluate the cardiovascular system. • 10. Know the common pulse points and venipuncture sites for common species of animal. 2 5/5/15 The Cardiovascular System • Vocabulary Fundaments: Be able to define, describe, or identify the terms on pages 338 and 339. The Cardiovascular System • Blood continuously flows through a animal’s body through the heart. • Blood is propelled by a beating, pumping m uscular heart. • Blood vessels are: Arteries, arterioles, capillaries, v enules, v eins 3 5/5/15 The Cardiovascular System • Blood cycles through the body in a “figure 8” • Circulation can be divided into two categories: Pulmonary circulation (lungs) Systemic c irculation (body) 4 5/5/15 The Heart • The base of the heart is rounded at the cranial end. • The apex of the heart is more pointed at the caudal end • The heart is located in the middle of the thoracic cavity, between the two lungs, in an area called the mediastinum. • The apex is shifted to the left and sits more ventrally. 5 5/5/15 6 5/5/15 The Heart • The heart lies in a fibrous sac called the pericardium, or pericardial sac. • The pericardium, or serous pericardium, has a visceral layer and a parietal layer. • The pericardial space is filled with a small amount of pericardial fluid. 7 5/5/15 The Heart • The heart wall is made up of three separate layers of tissue: Epicardium Myocardium Endocardium • The endocardium covers the papillary muscles as well. 8 5/5/15 The Heart • The heart is composed of m yocardium, or specialized heart muscle tissue. • There are four chambers in the mammalian heart: Right and left atria Right and left v entricles 9 5/5/15 The Heart • The atria sit on the top of the heart to form the base. (Atrium = singular) • The atria receive blood returning to the heart. • The r ight and left atria are separated by the interatrial septum. • When filled with blood the right and left atrial contract and push blood down into the right and left ventricles. 10 5/5/15 The Heart • The auricles are blind pouches that are a part of the atria. • The interventricular grove is formed by the interatrial septum and the interventricular septum. • The interventricular grove contains coronary blood vessels and fat. 11 5/5/15 The Heart • The ventricles sit below the atria. • The ventricles pump blood to the body and the lungs. The right ventricle pumps blood to the lungs. The left v entricle pumps blood to the body. • The ventricles are separated by the interventricular septum. The Heart • There are four one-way valves that control blood flow through the heart: Right Atrioventricular Valve (Tricuspid) Left Atrioventricular Valve (Bicuspid or Mitral) Pulmonary Semilunar Valve Aortic Semilunar Valve 12 5/5/15 The Heart • There are three components to the Right and Left Atrioventricular Valves: Leaflets or Cusps Chordae tendineae Papillary muscles 13 5/5/15 The Heart • The “ skeleton” of the heart is located between the atria and the ventricles, and is made up of four dense fibrous connective tissue rings. • The tissue: Separates the atria and the ventricles Anchors the heart valves Serves as a point if attachment for the myocardium Serves as electrical insulation between the atria and the ventricles 14 5/5/15 The Heart • The heart has its own blood supply. • The coronary arteries branch off the aorta and carry oxygenated blood to the myocardium. • The coronary veins carry deoxygenated blood from the myocardium back to the right atrium of the heart. 15 5/5/15 The Heart • The cardiac muscle creates its own electrical impulses and produces its own contractions and relaxation. • There are nerves that slow or speed the heart, but they are not necessary for cardiac contractions. • Cardiac conduction system: SA Node AV Node Right and left AV bundles Right and left bundle branches Purkinje fibers 16 5/5/15 The Heart • The cardiac cycle is made up of one complete heartbeat. • There is one cycle of atrial contraction and one cycle of ventricular contraction. Systole = active contraction and depolarization of the myocardium Diastole = relaxation and repolarization of the myocardium • Each heart chamber does through a cyclic period of systole and diastole to complete one cardiac cycle. • The chamber contractions are sequential, not at the same time. 17 5/5/15 The Heart • The normal heart sounds are produced by the heart valves snapping closed. • One cardiac cycle produces two distinct heart sounds: First heart sound “Lub” is produced by the right and left AV v alves c losing. Occurs after atrial systole. Second heart sound “Dub” is produced by the pulmonary and aortic v alves c losing. Occurs after ventricular systole. 18 5/5/15 The Heart • Abnormal heart sounds can be heard when the valves are not closing properly. • Abnormal heart sounds are r eferred to as heart murmurs. • Valvular insufficiency = one or more values do not close completely • Valvular stenosis = one or more valves do not open properly. The Heart • Reference Web Site: http://www.vetgo.com/cardio/ 19 5/5/15 The Heart • Cardiac Output ( CO) is the volume of blood that is ejected from the left ventricle over a period of time, usually defined as one minute. • CO = Stroke volume ( SV) X Heart r ate (HR) • SV = Represents the relative strength of the heart The Heart • Stroke Volume is determined by four factors: 1) Preload 2) Contractility 3) Relaxility 4) Afterload 20 5/5/15 The Cardiovascular System • The normal heart rate for each species is set internally and is dependent on the resting rate of SA node depolarization. • Outside factors increase or decrease the HR. 21 5/5/15 22 5/5/15 The Circulatory System • Arteries are blood vessels that carry blood away from the heart. • Pulmonary circulation carries deoxygenated blood from the heart to the lungs. • Systemic circulation carries oxygenated blood to body tissues. • Arteries are usually paired The Circulatory System • There are two types of arteries: Elastic, such as the aorta Muscular, such as the arterioles 23 5/5/15 The Circulatory System • Capillaries are the microscopic blood vessels found in tissues from branching arterioles. • Capillaries occur in groups call capillary beds or capillary networks. • Capillary walls are one endothelial cell thick • The exchange of gasses, nutrients, and waste products occurs at this level The Circulatory System • Veins carry blood towards the heart. • Pulmonary veins carry oxygenated blood from the lungs back to the left atrium. • Systemic veins carry deoxygenated blood from body tissues back to the right atrium. 24 5/5/15 The Circulatory System • Capillaries join together to form venules and venules join together to form veins. • Many veins have one-way valves present. • Muscular m ovements and values insure that the venous blood is returned to the heart. • All systemic veins drain into the cranial or caudal vena cava. 25 5/5/15 26 5/5/15 27 5/5/15 The Circulatory System • A fetus r eceives oxygen from the blood of its mother. • Fetal lungs are not used for gas exchange. • Fetal lungs only need enough oxygen to keep the tissues alive. • Gas exchange occurs through the placenta and umbilical cord The Circulatory System • On the first breath after birth. • The lungs inflate and the new born starts to oxygenate its own blood. • The foramen ovale and ductus arteriosus close so that the lungs are no longer bypassed in circulation. 28 5/5/15 29 5/5/15 30 5/5/15 The Circulatory System • A pulse is the rate of alternating stretching and recoiling of elastic fibers in an artery as blood passes through with each heartbeat. • A clinical pulse evaluates the regularity of pulsations and their strength. • Auscultation is not a true pulse. • There should be one pulse for each heartbeat. The Circulatory System • The pulse should be the same for each heartbeat. • Most often the pulse is felt on superficial arteries lying against firm surfaces, such as bones. • Generally, large animals have slower pulses and small animals have faster pulses. 31 5/5/15 The Circulatory System • Blood pressure ( BP) is the measurement of of the amount of pressure that flowing blood exerts against arterial walls. • BP is dependent on: Heart rate Stoke v olume Diameter and elasticity of the artery Total blood volume The Circulatory System • Blood pressure varies during the cardiac cycle. • Systolic is the highest number • Diastolic is the lowest number • Mean Arterial Pressure (MAP) is the average pressure during one cardiac cycle. • MAP = (CO X SVR) + CVP 32 5/5/15 The Circulatory System • Blood pressure can be measured by: Oscillometric method, where a cuff is placed over an artery and the cuff measures the magnitude and and frequency of the pulsations. Doppler ultrasound, where a transducer is attached to a sphygmomanometer and systolic BP is measured. Direct method, where a catheter is placed in an artery and the BP is measured directly from circulation. The Cardiovascular System • Indirect m ethods of monitoring the CV System: Auscultation of the thorax Peripheral artery palpation Arterial BP evaluation Thoracic radiography Electrocardiography Echocardiography 33 5/5/15 The Cardiovascular System • Electrocardiography ( EKG or ECG) is based on the electrical activity of the heart. • The EKG detects the myocardial impulses on the surface of the body and produces a graphic representation. • The components of a EKG are: P wave QRS complex T wave 34 5/5/15 The Cardiovascular System • Echocardiography, or an ECHO, is a common cardiac ultrasound procedure. • Sound waves are bounced off the heart to watch the heart beat and blood flow. • ECHO’s are used to evaluate the size, shape, and movement of the heart and its various parts. 35 5/5/15 The Cardiovascular System • Two-dimensional echocardiography produces a cross section of of the heart, and gives the ability to see the heart working in real time. • Doppler echocardiography adds color to the two dimensional image and is useful for evaluation of valvular stenosis or valvular insufficiencies. 36 5/5/15 The Cardiovascular System • Superficial blood vessels can be used to perform venipuncture to collect blood samples, administer IV medications, and place IV catheters. • The external jugular vein is the most common site for venipuncture. • The superficial caudal epigastric vein (milk vein) can use used in dairy cattle but is not desirable. • In ruminants and r odents the coccygeal vein can also be used. 37 5/5/15 38 5/5/15 39 5/5/15 40