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Lecture Three Amino acids & Peptides Dr. Khalidah Merzah Amino acids and peptides Properties of Amino Acids • Capacity to polymerize • Novel acid-base properties • varied structure and chemical functionality • Chirality •Steroisomers / enantiomers •Biological system only synthesize and use L-aminoacids Essential/Non-Essential Amino Acids • Essential –histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine • Non-essential – alanine, arginine*, aspartate, asparagine, cysteine*, glutamate, glutamine, glycine*, proline*, serine, tyrosine* Protein Nomenclature • Peptides 2 – 50 amino acids • Proteins >50 amino acids • Amino acid with free α-amino group is the amino-terminal or N-terminal residue • Amino acid with free α-carboxyl group is the carboxyl-terminal or C-terminal residue • Three letter code – Met-Gly-Glu-Thr-Arg-His • Single letter code – M-G-E-T-R-H