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Keystone Review by Topic/Module (2015) Name _____________________________ Module A Topic 1: Basic Biological Principles Terms to Know: Biology Cell Eukaryote Organ Organelle Organ System Organism Prokaryote Tissue Concepts to Know: Characteristics of Life Made of ____________ -Smallest unit of life -Uni- or multicellular Use energy -Autotroph: obtains energy from the _____ -Heterotroph: obtains energy from ________ __________________ -Asexual: one parent forms offspring (clone) -Sexual: one (haploid) cell from two parents form 1st cell of new organism Respond to Stimuli/ Environment -Ex: ___________________ ______________________ ______________________ Universal ___________ ____________________ -DNA ________ & _________ -Growth: increase in size of organism -Development: changing in form through a life cycle Maintain Homeostasis -Keep/ maintain a __________________ __________________ __________ over time -Evolve Structure & Function o Evolution has led to structures having certain functions to allow for survival Teeth structure (herbivores vs. carnivores) Opposable thumbs Organization of Cells & Living Things Atoms Molecules Organelles _________ _______________ __________________ __________________________________ ___________________ Prokaryotic vs. Eukaryotic Cells Prokaryotic Nucleus Plasma Membrane Cytoplasm Ribosomes Membrane-bound Organelles DNA Eukaryotic Common parts of the Cell 1. _________________ 2. _________________ Animal Cells vs. Plant Cells -Cell Wall -Nucleus -Central Vacuole -Plasma Membrane -Centrioles -Ribosomes -Chloroplast -Rough ER -Golgi Apparatus -Small Vacuoles -Lysosomes -Smooth ER -Mitochondria Function 3. _________________ Plant 4. _________________ Both Animal Keystone Review by Topic/Module (2015) Topic 2: The Chemical Basis for Life Terms to Know: Adhesion Amino Acid Atom Biological Macromolecule Carbohydrate Catalyst Cohesion Concentration Enzyme Freezing Point Lipid Molecule Monomer Nonpolar Nucleic Acid Organic pH Polar Protein Specific Heat Capacity Concepts to Know: Atoms & Molecules o Atoms can bond together to form molecules Number of bonds they can form is due to the number of _______________ in their outer shell Properties of Water o Oxygen can form TWO bonds and Hydrogen can form ONE bond, so: o o o o Water is a _____________________________ because of its differences in charge (not balanced) Polar substances (like water) and nonpolar substances DO NOT MIX because of the differences in charge Example: __________________________________ Because water is polar, it can bond to other water molecules and other polar substances, creating hydrogen bonds Hydrogen Bonds Allows for ______________________ (water sticking to itself) Allows for ______________________ (water sticking to other things) Gives water ________________________________ (resists changes in temperature) Allows water to expand when it freezes (less dense) Significance of Carbon o Carbon forms __________ bonds o It can bond in different ways which allows it to make diverse molecules Biological Macromolecules C H O N Carbohydrates Lipids Proteins Nucleic Acids P S Monomer Polymer Example Function Biochemical Reactions (reactants, products, dehydration synthesis, hydrolysis) o Reactants Products o Dehydration Synthesis: removing water to build molecules o Hydrolysis: adding water to break apart molecules Energy in Biochemical Reactions o ATP!!!!!!!!! o ATP ADP ATP cycle Enzyme Structure & Function o Biological catalysts: speed up chemical reactions without being consumed or changed o Temperature: too high/low will cause the enzyme to denature (change shape) and not work o pH: too acidic (low)/basic (high) will do the same thing as wrong temperature o Concentration: saturation is when the reaction rate has been maximized and adding more substrate will not increase the reaction rate Keystone Review by Topic/Module (2015) Topic 3: Bioenergetics Terms to Know: ATP Cellular Respiration Chloroplast Electron Transport Chain Photosynthesis Concepts to Know: Photosynthesis (purpose: to capture sunlight energy in glucose until it can be transferred to ATP) o Chloroplasts Unique to ________________________ ______________________ of photosynthesis o Light Reactions Take in __________ and ___________; water is split by light and oxygen is released ATP and NADPH are made o Calvin Cycle Carbon dioxide (from the atmosphere) is taken in, ATP and NADPH are used as “fuel” and glucose is made Cellular Respiration o Aerobic vs. Anaerobic Respiration Aerobic: _______________ oxygen (Kreb’s cycle & ETC; in mitochondria) Anaerobic: _____________________ oxygen (glycolysis; in cytoplasm) o Mitochondria Plants and animals have them Location of _________________________________ part of cellular respiration o Glucose & ATP Energy from the sun is stored in glucose until it can be transferred into ATP Photosynthesis energy changes: _________________________________________________ Cellular Respiration energy changes: _________________________________________________ o Glycolysis In _______________________ No oxygen needed ___________________________ use it to make some ATP from glucose o Electron Transport Chain In _______________________ Needs oxygen Releases more ATP from original glucose molecule Done by ____________________________ ONLY Topic 4: Homeostasis & Cell Transport Terms to Know: Active Transport Carrier (transport) Protein Cell (Plasma) Membrane Concentration Gradient Diffusion Endocytosis Endoplasmic Reticulum Exocytosis Facilitated Diffusion Golgi Apparatus Hypertonic Hypotonic Impermeable Isotonic Mitochondrion Nucleus Osmosis Passive Transport Permeable Pumps (ion or molecular) Semipermeable Keystone Review by Topic/Module (2015) Concepts to Know: Cell Membrane Structure & Function (AKA PLASMA MEMBRANE) o Function: ______________________________________ Diffusion & Osmosis o Diffusion: any movement of molecules from high to low concentration o Osmosis: movement of a solvent (__________________) from high to low concentration Facilitated Diffusion: o Passive Transport o Uses transport protein o How __________________ moves into cells Active Transport vs. Passive Transport Sodium-Potassium Pump o Active Transport o Uses Transport Protein/Carrier Protein/Ion Pump o Exchanges 3 sodium ions out of the cell to bring 2 potassium ions into the cell o Allows things to happen like your heart muscle cells to contract, nerves to send signals Exocytosis and Endocytosis o Exocytosis: moves substances _________ the cell o Endocytosis: moves substances _________ the cell Pinocytosis (______________) & Phagocytosis (_____________) Organelles Involved in Transport (How is each involved?) o Nucleus ________________________________________________________________________________ o Cytoplasm _______________________________________________________________________________ o ER ____________________________________________________________________________________ o Golgi Apparatus __________________________________________________________________________ o Mitochondria ____________________________________________________________________________ Homeostasis: ____________________________________________________________________________________ o Examples: ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ ________________________________________________________________________________ Keystone Review by Topic/Module (2015) Name __________________________ Module B Topic 5: Cell Growth & Reproduction Terms to Know: Anaphase Cell Cycle Chromosomes Crossing Over Cytokinesis DNA Replication Gamete Interphase Meiosis Metaphase Mitosis Nondisjunction Prophase Telophase Concepts to Know: Asexual vs. Sexual Reproduction o Asexual Reproduction: ____ parent cell (___________) divides to create ______ (________) cells (like cloning) o Sexual Reproduction: ______ parent cells (both ___________) unite to form first cell of offspring (_________) Cell Cycle: life cycle of the cell o Interphase: ____________________________________________ o Mitosis: ______________________________________________ o Cytokinesis: ___________________________________________ Mitosis o Purpose: ____________________________________________ Meiosis o Purpose: ____________________________________________ Genetic variation through meiosis o Crossing over: ____________________________________________________________________________ o Independent Assortment: ___________________________________________________________________ Keystone Review by Topic/Module (2015) Topic 6: Genetics (& DNA) Terms to Know: Allele Chromosomes Cloning Co-dominance DNA Replication Dominant Gene Gene splicing Gene therapy Genetically Modified Organism Gene Recombination Genetic Engineering Genetics Genotype Incomplete Dominance Inheritance Multiple Alleles Nondisjunction Phenotype Polygenic Trait Recessive Semiconservative Sex-linked Trait Transcription Translation Concepts to Know: Heredity, traits, genes, chromosomes o Heredity: a trait is “heritable” if it can _____________________________________ ______________: a molecule that carries genetic information to tell the cell when to make which proteins __________: segment of DNA that codes for a particular protein ____________: form of a gene ___________________: made of DNA and proteins; contains lots of genes Mendel’s laws o Law of _________________________: each allele segregates (separates) into different gametes o Law of ________________________________________: genes on separate chromosomes assort into gametes independently Punnett Squares (Mendelian and non-Mendelian) o Punnett Square: used to determine ____________________________________________________________ __________________: trait that always shows if present (capital letter) __________________: genetic make-up (ex – Bb) __________________: two of the same allele (true-breeding) __________________: one allele is not completely dominant over the other (ex – red, pink, & white) __________________: physical characteristic (ex – blue eyes) __________________: traits that result from many genes interacting (height, skin color) __________________: both alleles show up (ex – red, roan, & white) __________________: trait that only shows if it’s the only type present (lower case letter) __________________: genes with more than 2 possible alleles (blood) __________________: two different alleles (hybrid/ carrier) DNA Structure and function o Shape: __________________________________ o Bases: __________________________________ RNA structure and function (Bases: __________________) o mRNA _________________________________ o tRNA __________________________________ o rRNA __________________________________ Transcription o Purpose: __________________________________ o Location: __________________________________ Translation (Genetic code) o Purpose: __________________________________ o Location: __________________________________ Mutations Original: Biotechnology (cloning, genetic engineering, etc.) o Clone: identical copy of a cell or organism o Genetic Engineering: inserting genes from one organism into another to get it to produce the foreign protein Example: ________________________________________________________________________ Example: ________________________________________________________________________ o Genetically Modified Organism: ______________________________________________________________ Keystone Review by Topic/Module (2015) Topic 7: Theory of Evolution Terms to Know: Allele Frequency Competition Embryology Endosymbiosis Evolution Extinction Fossils Founder Effect Genetic Drift Homologous Structure Natural Selection Speciation Vestigial Structure Concepts to Know: Genetic variation o Variation: differences in a population Examples: ________________________________________________________________________ o More variations make for a more stable population that can survive a changing environment better Theory of evolution by natural selection o Natural selection: beneficial traits that allow for survival are passed on to future generations Survival of the fittest Evidence for evolution o Fossil record: shows how species have _________________________________ o Embryology: similarities in development shows common ancestors o Molecular Biology: more similarities in DNA sequences and proteins = ________________________________ o Homologous Structures: similar in structures but different in _______________________ Example: _____________________________ o Vestigial Structures: structures that have lost their _______________________________________ Example: _____________________________ Selection Pressures o Directional Selection o Stabilizing Selection o Disruptive Selection Microevolution (founder effect, bottleneck effect, etc.) o Gene flow: genes move back and forth between populations as organisms migrate o Genetic Drift Bottleneck Effect: an event (flood, fire, etc.) wipes out most of the population and the resulting population does not resemble the original population Founder Effect: a new population is started from part of an original population in a new area o Isolation (keeps species separate) Reproductive isolation: Geographic Isolation: populations are physically separated so they can’t interbreed Behavioral Isolation: mating/courtship differences Temporal Isolation: mating seasons do not match up Keystone Review by Topic/Module (2015) Topic 8: Ecology Terms to Know: Abiotic Biogeochemical Cycles Biome Biosphere Biotic Community Consumer Decomposer Ecology Ecosystem Energy Pyramid Energy Transformation Environment Food Chain Food Web Habitat Limiting Factor Nonnative Species Population Producer Species Succession Symbiosis Trophic Level Concepts to Know: Interdependence of living things o _______________________________________________________________________________________ Flow of energy in ecosystems (food chains/webs) Trophic levels Competition, predation, symbiosis (three types) o Competition: going after the same resources (land/food) among same or different species o Predation: one species eating another o Symbiosis: close relationship between two species Mutualism: _____________ benefit Commensalism: _________ benefits, other is ________________________ Parasitism: _________ benefits, other is ____________________________ Biogeochemical Cycles: water/hydrologic, carbon, oxygen, nitrogen, phosphorus, sulfur Succession o Primary Succession: community started ________________________________________________________ o Secondary Succession: community started _______________________________________________________ Population growth/limits Effects of human interactions Biomes