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Biomedical Imaging Dr Mohamed El Safwany, MD. Contents • Mammography Mammography Intended learning outcome • The student should learn at the end of this lecture Clinical mammographic techniques . Introduction and History • Breast cancer is 2nd only to lung cancer as cause of death in women – Very treatable with early detection! • Mammography became a reliable diagnostic tool in 1950s when industrial x-ray film introduced Definition of breast cancer: • Cancer that forms in tissues of breast, usually ducts (tubes that carry milk to nipple) and lobules (glands that make milk). • Occurs in both men and women (male breast cancer is rare) Principles Of Breast Cancer • Pt.s in early stages respond well to treatment • Patients with advanced disease do poorly • Earlier diagnosis, better chance of survival • Mammography is tool for early detection Diagnostic Mammogram • For woman presenting with clinical evidence of breast disease, palpable mass or other symptom • Uses specific projections to – Rule out cancer – Demonstrate suspicious area seen on screening mammogram Breast Anatomy • Lobule size is affected by age and hormones • Involution: process of decreasing lobule size with age and after pregnancy Anatomy (cont’d) • Breasts vary in size and shape • Consist of glandular, fat, and fibrous tissue Anatomy • The breast tapers anteriorly ending in the nipple • Encircled by areola: area of pigmented skin • Breasts are supported by Cooper’s ligament Female breasts are divided into 15 – 20 lobules • Base of breast overlies pectoralis major and serratus anterior muscles • Part of breast extends into axillary fossa Typical Mammography Unit Equipment is C-arm SID is fixed at 24 – 26” Mammography Equipment • Dedicated units have high-frequency generators • Provide more precise control of kVp, mA, and exposure time • Specially designed to produce high-contrast and high-resolution images Mammography uses • Low kVp : 25 – 28 • AEC Automatic Exposure Control • Anode material made of molybdenum, with rhodium target • Grid with ratio: 4:1, or 5:1 200 lines/inch Magnification • Increases visibility of small structures • Radiation dose increases with magnification Compression Device • Compression decreases thickness of breast, magnification and scattered radiation • Increases contrast • Reduces motion unsharpness • Reduces dosage Compression Device Made of firm plastic Amount of compression: between 25 and 40 pounds pressure Compression may be uncomfortable! Screen-Film Systems • Mammography cassettes contain a single screen • Mammographic film is single emulsion • Occasionally, extended time processing is used – (reduces dose and increases contrast) Digital Mammography State of the art! • No film or chemical processing • Images easily sent over internet • Much better definition Procedure • Complete, careful history and physical assessment – Take notes on location of scars, palpable masses, skin abnormalities, and nipple alterations • Examine previous mammograms for positioning, compression, and exposure factors Procedure (con’t) • Patients dress in open-front gown • Breasts must be bared for imaging – Cloth will cause image artifact • Remove deodorant and powder from axilla and breast – Can mimic calcifications on image Procedure (cont’d) • Explain procedure to pt., including possibility for additional projections • Consider natural mobility of breast before positioning • Support breast firmly so that nipple is directed forward • Profile nipple, if possible Positioning Procedure • Apply proper compression to produce uniform breast thickness – Essential to high-quality mammograms • Place ID markers Routine mammography projections Craniocaudal (CC) Mediolateral oblique (MLO) Craniocaudal Projection Patient position – Standing or seated facing IR holder • Part position – Elevate inframammary fold to maximum height – Adjust IR height to inferior surface of breast – Gently pull breast onto IR holder with both hands while instructing patient to press chest to IR holder Craniocaudal Projection • Arrange breast on film so nipple is in profile and maximum amount of breast tissue is radiographed • CR – Perpendicular to base of breast • Structures – Central, subareolar, medial fibroglandular breast tissue, posterior pectoral muscle Craniocaudal Positioning (cont’d – Immobilize breast with one hand – Use other hand to move opposite breast out of image – Shoulder relaxed in external rotation Craniocaudal Projection (cont’d) – Rotate head away from breast being examined (watch out for hair!) – – Lean pt. toward machine Compress breast slowly until skin taut Mediolateral Oblique Projection • Position – – – – Center breast with nipple in profile, if possible Hold breast up and out Compress breast slowly until taut Pull down on abdominal tissue to open inframammary fold Mediolateral Oblique positioning – Instruct pt. to hold opposite breast laterally, out of anatomy of interest – Exposure on suspended respiration – Release compression immediately! Mediolateral Oblique • Open inframammary fold • Deep and superficial breast tissues well separated • Retroglandular fat well seen • Uniform tissue exposure – If compression is adequate Mediolateral Oblique • Degree of obliquity is 30° to 60° • Depends on body habitus – Tall, thin patients require steeper angulation • CR perpendicular to base of breast • Structures – lateral aspect of breast and axillary tail Male Mammography • Approximately 1000 males develop breast cancer every year • Standard CC and MLO are obtained • Males not screened- mammogram only if lump discovered Gynecomastia CC view ( lesion) Needle Localizations • Used to localize breast lesions before surgery • Special, open-hole plate may be used for ease of localization – Plate contains grid to plot coordinates – Operative stereotactic surgery may be used Needle Localization Text Book • David Sutton’s Radiology • Clark’s Radiographic positioning and techniques Assignment • Two students will be selected for assignment. Question • Define value of compression device in mammographic techniques? Thank You 43 Thank you for your attention!