Download PHS 398 (Rev. 9/04), Biographical Sketch

BIOGRAPHICAL SKETCH
Fei, Baowei
NAME:
eRA COMMONS USER NAME: BAOWEIFEI
Assistant Professor
Georgia Cancer Coalition Distinguished Scholar
POSITION TITLE:
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
DEGREE
YEAR(s)
FIELD OF STUDY
Case Western Reserve University, Ohio
Doctor of Philosophy
Systems Engineering
Case Western Reserve University, Ohio
Master of Science
Computer Science
Shanghai Jiao Tong University, Shanghai
Doctor of Engineering
Biomedical Engineering
Xi’an Jiaotong University, Xi’an
Master of Engineering
Biomedical Engineering
Xi’an Jiaotong University, Xi’an
Bachelor of Science
Biomedical Engineering &
Instrumentation
A. Personal Statement
Currently, I lead the Quantitative BioImaging Laboratory (QBIL) at Emory University. I have experience of
leading NIH and DoD sponsored projects when I worked at Case Western Reserve University in Cleveland,
Ohio. I received comprehensive training in biomedical engineering, computer science, and radiology, which
includes two doctor degrees and two Master degrees. In 2006, my work entitled “New Imaging Method
Provides a „Before and After‟ Snapshot of the Prostate” was highlighted by the U.S. Department of Defense
Congressionally Directed Medical Research Program. In 2009, I was selected as a Georgia Cancer
Coalition Distinguished Scholar. In summary, I have a demonstrated record of successful and productive
research projects. In summary, I have a demonstrated record of successful and productive research
projects in an area that has significant impact on prostate cancer management that affect 1 in 6 men, and
my expertise and experience have prepared me to lead the proposed project.
B. Positions and Honors
2009Assistant Professor, Department of Radiology, Emory University, Atlanta, GA
2009Assistant Professor, Department of Biomedical Engineering, Georgia Institute of Technology
2005-2008
Assistant Professor, Radiology/Biomedical Engineering, Case Western Reserve University, Ohio
2005-2008
Member of Case Comprehensive Cancer Center, Case Western Reserve University, Ohio
2002-2004
Senior Research Associate, Biomedical Engineering, Case Western Reserve University,
2000-2001
Research Associate, Biomedical Engineering, Case Western Reserve University
1998-2000
Research Fellow, Biomedical Engineering, Nanyang Technological University, Singapore
1995-1998
Research Assistant, Biomedical Engineering, Shanghai Jiao Tong University, Shanghai
1993-1995
Principal Engineer, Department of Research & Development, Zhuhai Biolight Co. Guangdong
1990-1993
Engineer, Research Institute of Shanghai Medical Electronics Co. LTD., Shanghai
2009
2008-2009
2007-2009
2007-2009
2003-2009
National Institute of Health (NIH) Study Section ZRG1 SBIB
US Army Medical Research and Materiel Command (USAMRMC) Study Section
Maryland Technology Development Corporation (TEDCO) Grant Reviewer
Editorial Board of Clinical Medicine: Urology
Associate Editor, Medical Physics;
Honors (Selected from 18 awards/Honors)
2009
2006
Georgia Cancer Coalition Distinguished Cancer Scholar – Georgia State, USA
http://www.georgiacancer.org/res-dist-baowei_fei.php
Research work entitled “New imaging method provides a „before and after‟ snapshot of the prostate”
is highlighted on the US Department of Defense (DoD) Congressionally Directed Medical Research
Programs (CDMRP) website homepage (http://cdmrp.army.mil/highlights/2006.htm#2 )
2003
2001
1997
1990
Research work on molecular imaging for prostate cancer was included in the 2003 Annual Report of
US Department of Defense (DoD) Congressionally Directed Medical Research Programs (CDMRP).
http://cdmrp.army.mil/annreports/2003annrep/pdf/4_pcrp.pdf
Postdoctoral Traineeship Award, US Department of Defense Prostate Cancer Research Program.
Title: “Molecular Imaging for SPECT/MRI-guided Minimally Invasive Treatment of Prostate Cancer”
http://cdmrp.army.mil/search.aspx
The Outstanding Young Investigator Award in Biomedical Engineering of the Year 1997 in Shanghai,
The Society of Biomedical Engineering of Shanghai.
Admitted to the Extraordinary Youth Program of Xi’an Jiaotong University at 14 years of age
in 1986 and obtained the B.S. Degree in Biomedical Engineering at the age of 18 in 1990.
C. Selected peer-reviewed publications (Select from 33)
1.
B Fei, JL Duerk, DB Sodee, DL Wilson. “Three-dimensional semiautomatic warping registration of the
prostate and pelvis”, Academic Radiology, Vol. 12, pp. 815-824, 2005. PMID: 16039535
2.
B Fei, JL Duerk, DT Boll, JS Lewin, DL Wilson, “Slice to volume registration and its potential application
to interventional MRI-guided radiofrequency thermal ablation of prostate cancer,” IEEE Transactions on
Medical Imaging, Vol. 22, No. 4, pp. 515-525, 2003. PMID: 12774897
3.
B Fei, C Kemper, DL Wilson, A comparative study of warping and rigid body registration for the prostate
and pelvic MR volumes, Computerized Medical Imaging and Graphics, Vol. 27, pp.267-281, 2003.
PMID: 12631511
4.
B Fei, JL Duerk, DL Wilson, “Automatic 3D registration for interventional MRI-guided treatment of
prostate cancer,” Computer Aided Surgery, Vol. 7, No.5, pp. 257-267, 2002. PMID: 12582978
5.
B Fei, A Wheaton, Z Lee, JL Duerk, DL Wilson, “Automatic MR volume registration and its evaluation
for the pelvis and prostate,” Physics in Medicine and Biology, Vol. 47, pp. 823-838, 2002. PMID:
11931473
6.
B Fei, WS Ng, S Chauhan, CK Kwoh, “The safety issues of medical robotics,” Reliability Engineering
and System Safety, Vol. 73, No. 2, pp. 183-192, Jul. 2001.
7.
B Fei, H Wang, C Wu, M Chiu, Choline PET Imaging for Monitoring Early Tumor Response to
Photodynamic Therapy, Journal of Nuclear Medicine, 51(1): 130-138, 2010. PMID: 20008981
8.
Wang H, Fei B (corresponding author). “A modified fuzzy C-means classification method using a
multiscale diffusion filtering scheme”. Medical Image Analysis. 13(2):193-202, 2009. PMID: 18684658
9.
Cheng Y, C Samia, Meyers JD, Panagopoulos I, Fei B (co-corresponding author), Burda C. “Highly
efficient drug delivery with gold nanoparticle vectors for in vivo photodynamic therapy of cancer”.
Journal of American Chemical Society (JACS), 30(32):10643-7. 2008. PMCID: PMC2719258
10.
B Fei, H Wang, JD Meyers, D Feyes, NL Oleinick, JL Duerk, “High-Field Magnetic Resonance Imaging
of the Response of Human Prostate Cancer to Pc 4-based Photodynamic Therapy in an Animal
Model”, Lasers in Surgery and Medicine, 39(9):723-30, 2007. PMCID: PMC2719260
11.
X Chen, RC Gilkeson, B Fei (corresponding author), “Automatic 3D-to-2D registration for ct and dualenergy digital radiography for Calcification Detection”, Medical Physics, 34(12):4934-43, 2007. PMCID:
PMC2743028
12.
B Fei, HS Wang, RF Muzic, CA Flask, DL Wilson, JL Duerk, DK Feyes, NL Oleinick, Deformable and
rigid registration of microPET and high-resolution MR images for photodynamic therapy of cancer in
mice, Medical Physics, vol. 33, No. 3, pp. 753-760, 2006. PMID: 16878577
13.
B Fei, Z Lee, JL Duerk, JS Lewin, DB Sodee, DL Wilson, “Registration and fusion of SPECT, high
resolution MRI, and interventional MRI for thermal ablation of the prostate cancer,” IEEE Transactions
on Nuclear Science, Vol. 51, No.1, pp. 177-183, 2004.
14.
B Fei, Z Lee, DT Boll, JL Duerk, JS Lewin, DL Wilson, “Image registration and fusion for interventional
MRI-guided thermal ablation of the prostate cancer,” Peer-reviewed paper in Lecture Notes in
Computer Science Vol. 2879, pp. 364-372, Springer-Verlag Berlin Heidelberg, 2003.
D. Research Support
Georgia Cancer Coalition Distinguished Clinicians and Scientists Award (PI: Fei)
Source: Georgia Cancer Coalition – Georgia State
7/01/2009 – 6/30/2014
The major goal of this award to develop in vivo imaging technology for cancer research
Role: PI
P50CA128301 (PI: Meltzer, Hu, Goodman)
9/24/08-8/31/13
NIH/NCI
Emory Molecular and Translation Imaging Center (P50)
The goal is to create In vivo Cancer Molecular Imaging Center (ICMIC) at Emory University
Project 1 (PI: Schuster): Characterization of Prostate Cancer with FACBC PET/CT
Core C (Core Director: Votaw): Quantitative image and statistical analysis
Role: Co-investigator
1 RO1 CA 129356-01 (PI: Schuster)
09/1/07-08/31/12
NIH
18F-FACBC PET-CT for the Detection and Staging of Recurrent Prostate Carcinoma
The major goal of this research is to determine if PET imaging with anti-[18F]FACBC will lead to improved
patient care in the diagnosis and staging of prostate cancer and to elucidate the mechanism of its uptake
within malignant cells.
Role: Co-investigator
1P20CA128301-01 (PI: Bremner)
07/01/07-06/30/13
NIH
Neural Circuits in Women with Abuse and PSTD
The major goal of this project is to measure changes in brain function that occur during stress and the way
these may affect myocardial ischemia in patients with CVD and depression.
Role: Co-investigator
R01 MH073886 (PI: Bremner)
09/01/08-08/31/13
NIH/NIMH
Mechanisms of Depression in CVD
This project uses SPECT imaging of myocardial perfusion and PET imaging of brain blood flow during a
cognitive stress challenge in patients with heart disease with and without depression.
Role: Co-investigator
Completed Research Support
R21CA120536 (PI: Fei)
4/1/06-12/31/08
NIH/NCI:
Multimodality in vivo Molecular Imaging for Prostate PDT
The objective is to perform PDT of prostate cancer in a mouse model and to develop small animal imaging.
Role: PI
R21 MH080208-02 (PI: Bremner)
08/31/07-07/31/09
NIH
Benzodiazepine Receptor in PTSD
The major goal of this study is to use imaging of the benzodiazepine receptor in women with PTSD,
hypothesizing a reduction in benzodiazepine receptor binding in prefrontal cortex in women with abuse and
PTSD compared to women with abuse without PTSD and normal women.
Role: Co-investigator
Translational Research Program (PI: Fei)
7/15/08-12/31/08
Coulter Foundation
Dual-energy digital radiography for early detection of cardiac disease
The objective is to develop dual-energy digital radiography techniques as a screen tool for cardiac
diseases.
Role: PI
Presidential Research Initiative (PI: Fei)
7/1/07-12/31/08
Case Western Reserve University
In Vivo Imaging for Nanoparticle-based Cancer Therapy
The goal is to evaluate nanoparticles for cancer treatment and to develop imaging to monitor the therapy.
Role: PI
Cancer Center Project (PI: Fei)
3/1/06-8/30/07
Case Comprehensive Cancer Center
Multimodality in vivo Imaging for photodynamic therapy of prostate cancer
This application proposes to test a second-generation photosensitizing drug for photodynamic therapy of
prostate cancer in an animal model. Longitudinal images will be acquired to monitor tumor changes after
therapy.
Role: PI
Department of Defense (PI: Fei)
4/25/02-4/24/04
Department of Defense (DoD)
Molecular Imaging for MRI-guided Minimally Invasive treatment for Prostate Cancer
The overall goal of this project is to develop multimodality imaging for interventional MRI-guided
radiofrequency thermal ablation treatment for prostate cancer.
Role: PI