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Anaphylaxis is likely when all of the
following 3 criteria are met:
• Sudden onset and rapid progression of
symptoms.
• Life-threatening Airway and/or Breathing and/or
Circulation problems.
• Skin and/or mucosal changes (flushing, urticaria,
angioedema)
Adrenaline IM dose – adults:
0.5 mg IM
(= 500 micrograms = 0.5 mL of
1:1000) adrenaline.
Adrenaline IM dose – children
12 years: 500 micrograms IM (0.5 mL)
i.e. same as adult dose
300 micrograms (0.3 mL) if child is
small.
One ampoule of 1:1000 adrenaline
in 1 ml volume.
= This equals 1mg in 1 ml.
= This equals 1000 μg/ml.
Which one of the following penicillins
is natural ?
A- Amoxicillin
B- Ampicillin
C- Cloxacillin
D- Penicillin G
E- Oxacillin
Which one of the following penicillins
is used orally only?
A- Amoxicillin
B- Ampicillin
C-Cloxacillin
D-Penicillin G
E-Penicillin v
Which one of the following penicillins
is anti staphylococcal?
A-Amoxicillin
B-Ampicillin
C-Cloxacillin
D-Penicillin G
E-Penicillin v
All the following drugs are beta lactam
antibiotics except:
A- Amoxicillin
B- Ampicillin
C- Cloxacillin
D- Imipenem
E- Vancomycin.
Which one of the following penicillins
is anti pseudomonal?
A-Amoxicillin
B-Carbinicillin
C-Cloxacillin
D- Imipenem
E-Vancomycin.
Which one of the following penicillins is
not effective against gram negative
bacteria?
A-Amoxicillin
B-Carbinicillin
C-Cloxacillin
D- Imipenem
E-Ampicillin.
Which one of the following drugs is an
Injectable cephalosporin which has
half life of 8 hours and excreted in
the bile?
A- Cephalexin
B- Cefaclor
C- Ceftriaxone
D- Cefuroxime
E- Cefixime
Which one of the following drugs is
first generation cephalosporin?
A- Cephalexin
B- Cefaclor
C- Ceftriaxone
D- Cefuroxime
E- Cefixime
Which one of the following drugs is a
second generation cephalosporin?
A- Cephalexin
B- Cephalothin
C- Ceftriaxone
D- Cefuroxime
E- Cefixime
Which one of the following antibiotics
is not broad spectrum?
A- Ampicillin.
B- Cloxacillin
C- Ceftriaxone
D- Amoxicillin
E- Cephalexin.
Which one of the following drugs is
not used systemically?
A- Cephalexin.
B- Cephalothin.
C- Bacitracin.
D- Vancomycin.
E- Cefixime.
Concerning penicillins all the followings
are true except?
A-Penicillin g is given Parenterally.
B- Ampicillin is better absorbed than
amoxicillin.
C-penicillin v is given orally.
D-procaine penicillin is given IM.
E- Piparacillin is an anti pseudomonal
drug.
All of the following drugs can be
injected intravenously except:
A- Ceftriaxone
B- Cefotaxime
C- Cefuroxime Axetil
D- Benzathine Penicillin
E- Penicillin G
Which one of the following drugs has
the best activity against Penicillinase
producing gram negative bacteria?
A- Ampicillin
B- Oxacillin
C- Ampicillin + Cloxacillin
D- Amoxicillin + Clavulanic acid
E- Cefuroxime axetil
Concerning cephalosporins all the
following are true except:
A- First generation cephalosporins have better activity
on gram positive bacteria than third generation.
B- Cephalexin cab be used to treat soft tissue infections
C- Ceftriaxone is used in serious infections
D- Cefotaxime is used by injections
E- Cefuroxime axetil is not effective agaist gram
negative bacteria.
Which one of the following drugs can
be used safely in patients with severe
allergy to penicillins?
A-Ceftriaxone
B-Aztreonam
C-Vancomycin
D- Imipenem
E- Cefuroxime axetil.
Which one of the following drugs is
not a beta lactam antibiotic?
A-Meropenem
B-Carbinicillin
C-Ceftriaxone
D-Vancomycin
E-Ticarcillin
Which one of the following drugs is
known to induce toxic skin rash in EB
virus infection?
A- Cephalexin
B- Ceftriaxone
C- Ampicillin
D- Vancomycin
E- Clindamycin
Which one of the following antibiotics
is not useful in treating UTI?
A- Cephalexin.
B- Procaine Penicillin.
C- Cefuroxime.
D- Ceftriaxone.
E- Cefixime.
What is the most serious adverse
reaction to penicillin?
How Can you avoid it?
You are working in an outpatient clinic where you were
asked to manage a patient with fever(temp 39), you
diagnosed his condition as acute tonsillitis.
You prescribed procaine penicillin 1,200,000 iu twice
daily IM
Following the injection you were asked to urgently
resuscitate the patient as he loosed consciousness and
fell on the ground.
What are the possible causes?
How are you going to manage this patient?
You are working as a resident physician
at a medical word, you ere asked to
see a patient who developed vomiting
after an intravenous antibiotic.
How are you going to think?
A patient with meningitis and suspected
allergy to penicillin is in need of
effective intravenous beta lactam
antibiotic.
Which drug are you going to choose?
How are you going to administer the
drug?