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Lower Airway Larynx Tracheobronchial Trachea Bronchi Bronchioles Respiratory Terminal Tree (TB Tree) Hyoid Bone  Not part of the larynx.  The Hyoid bone is an anchor for the anterior muscles of the neck and is highly mobile. It also attaches to the muscles of the tongue to provide a stable or mobile base as the mobility of the tongue requires. Larynx  Voice Box  Function  Prevents aspiration  Generates sound for speech  Conducts air between the pharynx and trachea  Creates pressure changes Aspiration    Aspiration is the movement of food, liquid, vomit or a foreign substance into the trachea. Aspiration usually involves coughing or choking until the substance is removed if the patient has intact reflexes If large amounts of material or acidic, caustic materials (vomit) are aspirated, lung damage will result Increased Risk of Aspiration •Extremes of Age •Recent Meal •Delayed gastric emptying •Trauma •Depressed level of consciousness •Poor motor control Cartilages of the Larynx  Composed of nine cartilages Three unpaired cartilage  Thyroid (Greek for Oblong Shield)  Cricoid (Greek for ring)  Epiglottitis (Greek for “above glottis”) Three paired cartilages (six total)  Arytenoids (Greek for ladle)  Corniculates (Latin for horns – cornucopia)  Cuneiforms (Latin for wedge) 2. Arytenoid cartilage 3. Cervical trachea 6. Epiglottic larynx 7. Epiglottis 8. False Vocal Cords 9. Hyoid Bone 12. Subglottic larynx 15. True Vocal Cords Paired Cartilages  The Arytenoids, Cuneiforms, and Corniculates are all associated with movement of the vocal cords and are used in phonation. Thyroid Cartilage  The largest laryngeal cartilage is the thyroid cartilage  “Adam’s  Superior Apple” border has a Vshaped notch.  Suspended from hyoid bone.  Posterior wall is open.  The true and false vocal cords are found on the interior of the larynx. Vocal Cords  Two pairs of folds that protrude inward: pair – False cords  Lower pair – True cords  Upper  The space between the vocal cords is called the rima glottidis or glottis  Narrowest portion of the adult airway Vocal Cords Vocal Cords  Vocal Cord Abduction  Cords are opening or moving away from the midline  This occurs during inspiration  Vocal Cord Adduction  Cords are moving toward the midline or coming together  This occurs during expiration  http://www.entusa.com/normal_larynx.htm Epiglottis  Spoon-shaped cartilage which prevents aspiration by covering the opening of the larynx during swallowing.  The tongue and the epiglottis are connected by folds of mucous membranes which form a small space called the vallecula. Intubation  A device called a laryngoscope is used to visualize the laryngeal structures.  It is composed of a handle and one of two types of blades:  A curved blade (McIntosh)  A straight blade (Miller or Wisconsin)  A curved laryngoscope blade is inserted into the vallecula during intubation to lift the epiglottis indirectly.  A straight laryngoscope blade is used to directly lift the epiglottis during intubation Cricoid Cartilage      Resembles signet (class) ring. Inferior to Thyroid. Only complete ring of laryngeal structures. Inferior border is attached to the first C-shaped tracheal ring. The narrowest portion of the airway in an infant.  We use this fact when ventilating infants as infant ET tubes do not have cuffs to seal the trachea. Cricothyroid membrane  Connects the cricoid and thyroid cartilages  Is the site for an emergency airway  Cricothyrotomy Laryngeal Swelling Swelling (edema) at the glottis, subglottic or supraglottic region can cause stridor  Stridor is a high pitched crowing sound usually heard on inspiration from air traveling through a narrowed opening   Croup, Epiglottis, Foreign Body http://www.rale.ca/Stridor.htm Laryngospasm  A laryngeal reflex which will close the vocal cords inside the larynx  Laryngospasm results from  Extubations  Near drowning  Inhalation of noxious substances  Smoke inhalation Valsalva Maneuver  Forced expiratory effort against a closed glottis to increase intrathoracic pressure (defecation) or to inflate the eustachian tubes and middle ears (“clearing” of the ears on airplanes).  The larynx will tightly seal preventing air from escaping during physical work  Lifting, pushing, throat-clearing, vomiting, urination, defecation and parturition. Head Position Flexed Extended Histology of the Larynx  Above the vocal cords  stratified  Below squamous epithelium the vocal cords  pseudostratified  Trachea columnar epithelium to respiratory bronchioles Tracheobronchial Tree  Two Divisions  Cartilaginous  Airways Primarily conducting airways; no gas exchange.  Noncartilaginous  Airways Both conducting airways and sites of gas exchange.  Dichotomous Branching  Each airway divides into two “daughter” branches  Each division (bifurcation) gives rise to a new generation of airways  As airways divide, they become  Shorter  Narrower  More numerous Cartilaginous Airways  Trachea  Main Stem Bronchi  Lobar Bronchi  Segmental Bronchi  Subsegmental Bronchi Lobar Bronchi Trachea Generation 0  11 – 13 cm long and 1.5 – 2.5 cm wide.  Extends from Cricoid cartilage (6th cervical vertebrae) to the 2nd costal cartilage or 5th thoracic vertebrae.   C6 – T5 15 - 20 C-shaped cartilages supports the trachea.  Posterior wall is contiguous with esophagus.  Trachea  The end of the trachea is called the carina.  This is the division of the trachea into the right and left mainstem bronchi.  Air is 100% saturated with water vapor and is warmed to 37 °C (body temperature).  The carina is located at approximately T5 or the Angle of Louis.  The surgical opening into the trachea is called a tracheostomy.  2nd or 3rd tracheal ring. Main Stem Bronchi Generation 1  Trachea divides into the right and left mainstem bronchi – one for each lung  Right Mainstem is wider, shorter and more vertical   Branches  Left Mainstem  Branches  at a 25 degree angle at a 40 – 60 angle Infants  Both mainstem bronchi form a 55 angle with the trachea Newborn Complications of Intubation  During intubations, if the tube is advanced to far, the tube will usually go into the right mainstem bronchi.  Lung inflation will be absent on the left but present on the right.  Withdraw tube until bilateral sounds are heard.  Failure to hear lung sounds or visualize chest inflation on either side means the tube is probably in the stomach.  Extubate the patient and re-attempt the intubation. Aspiration  Children  Foreign who aspirate objects body usually lodged in right main stem bronchi secondary to the angle being less acute.  Wheezing on right or absent lung sounds (breath sounds). Lobar Bronchi Generation 2  Lobar Bronchi correlate to the number of lobes of the lung.  The right mainstem bronchi will divide into the right upper, right middle and right lower lobe bronchi.  The left mainstem bronchi will divide into the left upper and left lower lobe bronchi.  Segmental Bronchi  Generation 3  Correlate with the segments of the lung.  There are 10 segmental bronchi on the right.  There are 8 segmental bronchi on the left. Subsegmental Bronchi  4th to 9th Generations  1 to 4 mm in diameter  Connective tissue containing:  Nerves  Lymphatics  Bronchial Arteries Non-Cartilaginous Airways  Bronchioles 10th to 15th Generation.  1 mm in diameter.  Simple cuboidal epithelium.  No cartilage.   Terminal Bronchioles Less than 0.5 mm in diameter.  No cartilage (lack of support).  Cilia and mucous glands disappear.  Clara Cells appear  Inter-bronchiole connections called Canals of Lambert begin to appear.  Blood Supply to the Tracheobronchial Tree  Bronchial Blood Supply  Bronchial arteries nourish the tracheobronchial tree  The arteries arise from the aorta and follow the tracheobronchial tree as far as the terminal bronchioles.  Beyond the terminal bronchioles pulmonary arteries & capillaries feed the airways & alveoli.  Normal bronchial blood flow is approximately 1% of the cardiac output.  Also feed the mediastinal lymph nodes, pulmonary nerves, part of the esophagus and the visceral pleura. Review of TB Tree  Trachea  Mainstm Bronchi  Lobar Bronchi  Segmental Bronchi  Subsegmental Bronchi  Bronchioles – cartilage disappears  Terminal Bronchioles Site of Gas Exchange “The Respiratory Zone”  Consists of the respiratory bronchioles, alveolar ducts, and alveolar sacs, and alveoli.  Parenchyma, Acinus or Primary Lobule. Creative Commons Attribution Alveolar Epithelium  Two principal cell types:  Alveolar Type I Cells  Squamous pneumocyte  Broad thin cells.  95% of alveolar surface  0.1 m to 0.5 m thick  Alveolar  5% Type II Cells of alveolar surface  Cuboidal in shape  Responsible for secretion of pulmonary surfactant that reduce surface tension and keep the alveoli stable. Facts about the Lungs  There are 300 million alveoli in the lungs.  The surface area of the lungs is 75-85 square meters (Tennis Court).  The lung has 35 times more surface area then the skin. Additional Components of Alveolar Epithelium  Pores of Kohn  Small holes in the walls of interalveolar septa.  3 m to 13 m in diameter  Alveolar Macrophages or Type III alveolar cells.  Major role in removing bacteria and other foreign particles.  Interstitium  Gel-like substance between alveoli-capillary clusters that add support Lung  Extends from the diaphragm to 1-2 cm above the clavicles (about the 1st rib).  The lung apex is at the top of the lung and is somewhat pointed.  The base is broad and concave and lies at about the 6th rib or xiphoid process anteriorly, the 8th rib laterally, and the 11th rib posteriorly.  The right lung is larger and heavier than the left. Lung Lobes and Segments  Right lung  Three Lobes Upper, Middle, Lower  Divided by the Horizontal and Oblique fissures.   10  Segments Left lung  Two Lobes Upper and Lower  Divided by the Oblique fissures.  8 Segments LOBES AND SEGMENTS OF THE LUNGS RIGHT LUNG LEFT LUNG UPPER LOBE UPPER LOBE (UPPER DIVISION) • APICAL SEGMENT ANTERIOR SEGMENT • POSTERIOR SEGMENT •APICAL/POSTERIOR •ANTERIOR MIDDLE LOBE UPPER LOBE (LINGULA) •LATERAL •MEDIAL •SUPERIOR •INFERIOR LOWER LOBE LOWER LOBE •SUPERIOR •ANTERIOR BASAL •MEDIAL BASAL •LATERAL BASAL •POSTERIOR BASAL •SUPERIOR •ANTERIOR/MEDIAL BASAL •LATERAL BASAL •POSTERIOR BASAL Lung Fissures  Oblique Fissure  Found in the left and right lung  Separates the upper and lower lobes of both lungs  Horizontal  Found or minor Fissure only in the right lung  Separates the upper and middle lobes  Horizontal fissure  Oblique fissure Hilum  The hilum is where arteries, veins, bronchi, nerves and lymph vessels enter and leave the lung.  It is located on the medial border of the lung.