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ATRIAL FIBRILLATION Kay Abbott CNS Arrhythmia WHAT IS ATRIAL FIBRILLATION? AF is the most common cardiac arrhythmia 1.2million patients diagnosed in UK 200,000 new AF patients diagnosed annually 575,000 hospital admissions per year (1% of NHS Budget annually) 1 in 4 stroke patients admitted in AF Atrial fibrillation Association (January 2009) Pathology Chaotic electrical activity develops within the upper chambers of the heart (Atria) and completely takes over from SA node Atria no longer beat in an organised way and pump less efficiently Some impulses will be stopped by the AV node but ventricles will beat irregularly and possibly rapidly. Sinus Rhythm S Atrial Fibrillation S AV AV Causes High Blood Pressure Coronary Heart Disease Mitral valve disease (?Rheumatic Heart disease, Infection) Congenital heart disease Pneumonia Lung Cancer Pulmonary embolism Overactive thyroid Carbon monoxide poisoning Substance abuse (drugs, alcohol) Old age Symptoms of A.F. Palpitations Shortness of Breath Chest Discomfort Light Headedness/fainting Fatigue NO SYMPTOMS AT ALL ECG IN ATRIAL FIBRILLATION The signals causing the beating of the ventricles (black arrows) are irregular and a little rapid; the signals picked up from the fibrillating atrium (red arrows) are very rapid and cause only an irregular ripple effect on the baseline of the trace. TYPES OF ATRIAL FIBRILLATION PAROXYSMAL AF – multiple episodes of AF that cease within 7 days with no treatment PERSISTENT AF - LONGSTANDING AF – episodes lasting longer than 7 days or less than 7 days with treatment a one year duration continuous AF of more than ATRIAL FLUTTER What is Atrial Flutter Similar to Atrial Fibrillation but has some important differences Impulse originates in the right atrium (usually) and the atria beat very quickly and regularly at around 300 beats per minutes taking over from the sinus node AV node will not conduct all of these beats to the ventricles but allows every 2nd, 3rd or 4th beat through. Gives a regular ventricular heart rate of either 150bpm; 100bpm or 75 bpm. Causes of Atrial Flutter Share similar causes as Atrial Fibrillation More common in patients who have history of previous heart disease Men twice as more likely to suffer than women Often no one singular cause but a number of factors that increase the likelihood : – – – – – – – – – – – High Blood Pressure Ischaemic Heart disease Heart Valve Problems Cardiomyopathy Pneumonia Cardiac Surgery Pericarditis Overactive thyroid COPD Excess Alcohol Pulmonary embolism Atrial Flutter 1 impulse allowed through AV node Sinus Rhythm S Atrial impulse rate 300 divided by one impulse allowed through the AV node gives a Ventricular heart rate on the ECG of 75 bpm S AV AV What would ventricular rate be if 2 impulses allowed through? What would ventricular rate be if 3 impulses allowed through? Atrial Flutter The signals causing the beating of the ventricles (black arrows) are regular the signals picked up from the fluttering atrium (red arrows) are very rapid at a rate of approx 300 bpm and cause a saw-tooth appearance on the baseline of the trace. RISKS OF ATRIAL FIBRILLATION / ATRIAL FLUTTER Increased risk of stroke as blood in atria becomes stagnant which in turn increases risk of clot formation If rate not controlled then risk of clot formation higher and can also (in extreme cases) lead to heart muscle damage leading to heart failure TREATMENTS Drug Treatments: Stroke Prevention - Warfarin or Aspirin* Rate Control/Anti-Arrhythmic – Beta Blocker, Calcium Channel Blocker, Flecainide, Digoxin and/or Amiodarone Non Drug Treatments: Cardioversion Ablation CHADS2* / Congestive cardiac failure 1 Hypertension 1 Age 1 Diabetes 1 Stroke/TIA 2 CHA2DS2VASc Score Congestive Cardiac Failure 1 Hypertension 1 Age>75 2 Diabetes 1 Stroke/TIA 2 Vascular 1 Age>65 1 Sex Category 1 RAAF SERVICE Referrals from Hospital/GP/A&E ECG enclosed confirming AF Rapid Warfarin initiation Tests/OPD arranged Treatment Follow up for 6 months Referring Algorithm [care pathway] for all Patients Presenting with Atrial Fibrillation/Flutter ALL BOXES MUST BE COMPLETED OR REFERRAL WILL BE RETURNED DELAYING TREATMENT ECG must be enclosed confirming AF New Onset AF less than 1 year? Yes/No Unknown Onset – Symptomatic Yes/No Add patient to AF Register [for Primary Care] Unknown Onset – Asymptomatic Yes/No Onset of AF longer than 1 year Yes/No What is the patient’s heart rate? bpm Target Rate Control = 60–80 bpm at rest 1st Line: Beta Blockers - 2nd Line: Diltiazem/Verapamil - Digoxin = 1st line for Sedentary patients ANTI-COAGULATION – Please inform patient of referral for Warfarin Therapy Prompt anticoagulation reduces the risk of systemic thromboembolism. CHADS2 SCORE ………………. LIST OF CONTRAINDICATIONS TO ANTICOAGULANT THERAPY: - Active Bleeding - Non-Compliance - Active Peptic Ulcer - Oesophageal Varices - Bacterial Endocarditis - Patient Choice - Clotting Disorder - Pregnancy/Breast Feeding - Dementia (mmse<20) - Severe Hepatic Disease - Excessive Alcohol Intake (greater than 2-3 - Severe Hypertension >180/110 units per day for women, 3-4 for men) - Significant Renal Impairment (Creatinine clearance - History of Repeated Falls <10ml/min) - Inflammatory Bowel Disease - Within 24 Hours of Surgery Please sign below to confirm that there are no contraindications to long term anticoagulation. Upon receiving a signed form the RAAF service will automatically forward it to the anticoagulant clinic for early appointment. Name and Signature………………………………………………………Date…………………………. Oral anticoagulation should be initiated with a target INR of 2-3 and continued until further notice. A SIGNED FORM CONSTITUTES A REFERRAL FOR WARFARIN, THEREFORE THE PATIENT SHOULD BE COUNSELLED AS TO THE MERITS OF INITIATION OF WARFARIN AND THE CLINICAL BENEFITS/RISKS VERSUS ALTERNATIVE TREATMENTS BY THE REFERRING CLINICAL TEAM REFERRER to arrange following BLOOD TESTS: - Full Blood Count - Urea & Electrolytes Tests Date tests requested: …………………………….. - Liver Function Tests - Thyroid Function Patient Name: Unit No: NHS No: Referrer Name: GP/Hospital: Patient Address: Date of Birth: Referrer Contact Details: PLEASE FAX THIS FORM TO RAAF SERVICE, SOUTHEND HOSPITAL FAX NO. 01702 385965 TEL. NO. 01702 435555 ext 6078 Thank You Any Questions