Download Session-1-topics_in_ten

Topics in ten…
Bacteria
Bacteria
Bacteria
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Size (500nm – several um)
Genetics (HGT)
Gram type (peptidoglycan)
Metabolism
Reproduction
Pathogenesis
Viruses
Viruses
Viruses
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Size (30nm – several um)
Genetics - type
Proteins – env,
Reproduction
Epigenetics:
the study of changes in gene expression or cellular
phenotype, caused by mechanisms other than changes
in the underlying DNA sequence
Epigenetics:
the study of changes in gene expression or cellular
phenotype, caused by mechanisms other than changes
in the underlying DNA sequence
Prions
Prions are generally quite resistant to proteases, heat, radiation, and formalin treatments.
Effective prion decontamination relies upon protein hydrolysis or reduction or destruction of
protein tertiary structure.
Examples include bleach, caustic soda, and strongly acidic detergents such as LpH.
134 °C (274 °F) for 18 minutes in a pressurized steam autoclave may not be enough to
deactivate the agent of disease
Prions
Affected animal(s)
sheep, goat
cattle
mink[42]
white-tailed deer, elk, mule deer, moose[42]
cat[42]
nyala, oryx, greater kudu[42]
ostrich[43]
Disease
Scrapie[42]
Bovine spongiform encephalopathy (BSE), mad
cow disease[42]
Transmissible mink encephalopathy (TME)
Chronic wasting disease (CWD)
Feline spongiform encephalopathy (FSE)
Exotic ungulate encephalopathy (EUE)
Spongiform encephalopathy
(Has not been shown to be transmissible.)
Creutzfeldt–Jakob disease (CJD)[42]
Iatrogenic Creutzfeldt–Jakob disease (iCJD)
Variant Creutzfeldt–Jakob disease (vCJD)
Familial Creutzfeldt–Jakob disease (fCJD)
human
Sporadic Creutzfeldt–Jakob disease (sCJD)
Gerstmann–Sträussler–Scheinker syndrome
(GSS)[42]
Fatal familial insomnia (FFI)[44]
Kuru[42]