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HIV Resistance Publications - May to July/August 2009 Title Author Abstracts Presented at the XVIII International HIV Drug Resistance Workshop Journal Volume Issue June 2009, Florida Genetic determinants in HIV-1 Gag and Env V3 are related to viral response to combination antiretroviral therapy with a protease inhibitor. Ho SK AIDS - Epub ahead of print The dynamics of appearance and disappearance of HIV-1 integrase mutations during and after withdrawal of raltegravir therapy. Ferns RB AIDS - Epub ahead of print Nucleoside reverse transcriptase inhibitor-sparing regimen (nonnucleoside reverse transcriptase inhibitor + protease inhibitor) was more likely associated with resistance comparing to nonnucleoside reverse transcriptase inhibitor or protease inhibitor + nucleoside reverse transcriptase inhibitor in the randomized ANRS 121 trial Soulié, Cathia AIDS - July 2009 23 12 Additional HIV-1 mutation patterns associated with reduced phenotypic susceptibility to etravirine in clinical samples Kagan, Ron M AIDS - July 2009 23 12 The impact of transmission clusters on primary drug resistance in newly diagnosed HIV-1 infection Yerly, Sabine AIDS - July 2009 23 11 Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing Archer, John AIDS - June 2009 23 10 The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing firstline antiretroviral therapy Hosseinipour, Mina C AIDS - June 2009 23 9 Antiretroviral medication adherence and the development of class-specific antiretroviral resistance Gardner, Edward M AIDS - June 2009 23 9 Increased mutations in Env and Pol suggest greater HIV-1 replication in sputum-derived viruses compared with blood-derived viruses Wagner, Thor A AIDS - May 2009 23 8 Women exposed to single-dose nevirapine in successive pregnancies: effectiveness and nonnucleoside reverse transcriptase inhibitor resistance McIntyre, James A AIDS - April 2009 23 7 Antiretroviral drug susceptibility among drug-naive adults with recent HIV infection in Rakai, Uganda Eshleman, Susan H AIDS - April 2009 23 7 Tolerance and viral resistance after single-dose nevirapine with tenofovir and emtricitabine to prevent vertical transmission of HIV-1 The TEmAA ANRS 12109 Study group AIDS - April 2009 23 7 Comparison of Laboratory Methods for Analysis of Non-nucleoside Reverse Transcriptase Inhibitor Resistance in Ugandan Infants Jessica D. Church Aids Research and Human Retroviruses - July 2009 25 7 Pol Bootscanning Analysis of HIV Type 1 Can Exhibit Unexpected Recombinations Anne-Cécile Jeannot Aids Research and Human Retroviruses - July 2009 25 7 Analysis of HIV Type 1 gp41 and Enfuvirtide Susceptibility among Men in the United States Who Were HIV Infected Prior to Availability of HIV Entry Inhibitors Sarah E. Hudelson Aids Research and Human Retroviruses - July 2009 25 7 Comparison of HIV Type 1 Sequences from Plasma, Cell-Free Breast Milk, and Cell-Associated Breast Milk Viral Populations in Treated and Untreated Women in Mozambique Mauro Andreotti Aids Research and Human Retroviruses - July 2009 25 7 Characterization of Genetically Diverse HIV Type 1 from a London Cohort: Near Full-Length Genomic Analysis of a Subtype H Strain Vera Holzmayer Aids Research and Human Retroviruses - July 2009 25 7 Modulation of K65R Selection by Zidovudine Inclusion: Analysis of HIV Resistance Selection in Subjects with Virologic Failure Receiving Once-Daily Abacavir/Lamivudine/Zidovudine and Tenofovir DF (Study COL40263) Lisa Ross Aids Research and Human Retroviruses - July 2009 25 7 In Utero HIV Infection Is Associated with an Increased Risk of Nevirapine Resistance in Ugandan Infants Who Were Exposed to Perinatal Single Dose Nevirapine Jessica D. Church Aids Research and Human Retroviruses - July 2009 25 7 Current HIV Type 1 Molecular Epidemiology Profile and Identification of Unique Recombinant Forms in Jakarta, Indonesia Ivo N. Sahbandar Aids Research and Human Retroviruses - July 2009 25 7 Near Full-Length Genome Characterization of an HIV-1 CRF01_AE Strain in Jiangsu, China: Evidence of Two Independent Introductions from Fujian Dongmei Guo Aids Research and Human Retroviruses - June 2009 25 6 Phylogenetic Analysis of HIV-1 Reverse Transcriptase Sequences from 382 Patients Recruited in JJ Hospital of Mumbai, India, between 2002 and 2008 Alaka Deshpande Aids Research and Human Retroviruses - June 2009 25 6 Detection of Drug Resistance-Associated and Background Mutations in Human Immunodeficiency Virus Type 1 CRF01_AE Protease and Reverse Transcriptase Derived from Drug Treatment-Naive Patients Residing in Central Thailand Wattana Auwanit Aids Research and Human Retroviruses - June 2009 25 6 Human Immunodeficiency Virus Type 1 gp 41 Mutations in Proviral DNA among Antiretroviral Treatment-Naive Individuals from India Sourav Sen Aids Research and Human Retroviruses - May 2009 25 5 A Novel Codon Insert in Protease of Clade B HIV Type 1 Parris S. Jordan Aids Research and Human Retroviruses - May 2009 25 5 Structural Basis of Drug Resistance by Genetic Variants of HIV Type 1 Clade C Protease from India Abraham Joseph Kandathil Aids Research and Human Retroviruses - May 2009 25 5 Low Prevalence of Drug Resistance Transmitted Virus in HIV Type 1-Infected ARV-Naive Patients in Cambodia Janin Nouhin Aids Research and Human Retroviruses - May 2009 25 5 HIV Type 1 Drug Resistance in Adults Receiving Highly Active Antiretroviral Therapy in Abidjan, Côte d'Ivoire Debra L. Hanson Aids Research and Human Retroviruses - May 2009 25 5 High HIV Type 1 Prevalence and Wide Genetic Diversity with Dominance of Recombinant Strains But Low Level of Antiretroviral Drug-Resistance Mutations in Untreated Patients in Northeast Gabon, Central Africa Armel Mintsa-Ndong Aids Research and Human Retroviruses April 2009 25 4 HIV Type 1 Group M Subtype G in Cameroon: Five Genome Sequences Julie Yamaguchi Aids Research and Human Retroviruses April 2009 25 4 First Detection of a Novel HIV Type 1 CRF01_AE/07_BC Recombinant among an Epidemiologically Linked Cohort of IDUs in Jiangsu, China Hongxiong Guo Aids Research and Human Retroviruses April 2009 25 4 Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya. Steegen K AIDS Research and Therapy - June 2009 6 12 HIV-1 Resistance to First- and SecondGeneration Non-nucleoside Reverse Transcriptase Inhibitors Jade Ghosn AIDS Reviews 11 3 The Challenge of HIV-1 Antiretroviral Resistance in Africa in the Era of HAART Hakim Sendagire AIDS Reviews 11 2 Characterization and Structural Analysis of HIV-1 Integrase Conservation Francesca CeccheriniSilberstein AIDS Reviews 11 1 HIV-1 Genotypic Drug Resistance Interpretation Rules – 2009 Spanish Guidelines Carmen de Mendoza AIDS Reviews 11 1 Cohorts, trials, and evidence: expanding our confidence in guidelines for antiretroviral resistance testing. Volberding P Annals of Internal Medicine - July 2009 151 2 Natural Polymorphisms of HIV-1 Integrase and Inherent Susceptibilities to a Panel of Integrase Inhibitors. Low A Antimicrobial Agents and Chemotherapy Epub ahead of print Use of different inhibitory quotients to predict early virological response to Tipranavir in antiretroviral experienced HIV patients. Morello J Antimicrobial Agents and Chemotherapy Epub ahead of print Antiretroviral Drug Resistance Surveillance among Treatment-Naive Human Immunodeficiency Virus Type 1Infected Individuals in Angola: Evidence for Low Level of Transmitted Drug Resistance Inês Bártolo Antimicrobial Agents and Chemotherapy July 2009 53 7 Detection and Quantification of Minor Human Immunodeficiency Virus Type 1 Variants Harboring K103N and Y181C Resistance Mutations in Subtype A and D Isolates by Allele-Specific Real-Time PCR Andrea Hauser Antimicrobial Agents and Chemotherapy July 2009 53 7 Protease Inhibitor Resistance Analysis in the MONARK Trial Comparing First-Line Lopinavir-Ritonavir Monotherapy to Lopinavir-Ritonavir plus Zidovudine and Lamivudine Triple Therapy Constance Delaugerre Antimicrobial Agents and Chemotherapy July 2009 53 7 Treatment with the Fusion Inhibitor Enfuvirtide Influences the Appearance of Mutations in the Human Immunodeficiency Virus Type 1 Regulatory Protein Rev Valentina Svicher Antimicrobial Agents and Chemotherapy July 2009 53 7 Predictive Value of PharmacokineticsAdjusted Phenotypic Susceptibility on Response to Ritonavir-Enhanced Protease Inhibitors (PIs) in Human Immunodeficiency Virus-Infected Subjects Failing Prior PI Therapy Joseph J. Eron Jr Antimicrobial Agents and Chemotherapy June 2009 53 6 Susceptibility of Human Immunodeficiency Virus Type 1 to the Maturation Inhibitor Bevirimat Is Modulated by Baseline Polymorphisms in Gag Spacer Peptide 1 Kurt Van Baelen Antimicrobial Agents and Chemotherapy May 2009 53 5 Human Immunodeficiency Virus Type 1 Isolates with the Reverse Transcriptase (RT) Mutation Q145M Retain Nucleoside and Nonnucleoside RT Inhibitor Susceptibility Vici Varghese Antimicrobial Agents and Chemotherapy May 2009 53 5 Genotypic analysis of the protease and reverse transcriptase of non-B HIV type 1 clinical isolates from naïve and treated subjects. Monno L Antiviral Research - Epub ahead of print Evolution of drug resistance after virological failure of a first-line highly active antiretroviral therapy regimen in Uganda Steven J Reynolds Antiviral Therapy 14 4 HIV type-1 clade C resistance genotypes in treatment-naive patients and after first virological failure in a large community antiretroviral therapy programme. Orrell C Antiviral Therapy 14 4 In vivo selection by enfuvirtide of HIV type-1 env quasispecies with optimal potential for phenotypic expression of HR1 mutations. Goubard A Antiviral Therapy 14 Evolution and predictors of HIV type-1 drug resistance in patients failing combination antiretroviral therapy in Italy Simona Di Giambenedetto Antiviral Therapy 14 Resistance profiles after different periods of exposure to a first-line antiretroviral regimen in a Cameroonian cohort of HIV type-1-infected patients Alessandro Soria Antiviral Therapy 14 Historical resistance profile helps to predict salvage failure Mauro Zaccarelli Antiviral Therapy 14 Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype André Altmann Antiviral Therapy 14 Mutations in the thumb–connection and RNase H domain of HIV type-1 reverse transcriptase of antiretroviral treatmentexperienced patients Joshua M Waters Antiviral Therapy 14 Investigation of expert rule bases, logistic regression, and non-linear machine learning techniques for predicting response to antiretroviral treatment Mattia CF Prosperi Antiviral Therapy 14 Immunological responses during a virologically failing antiretroviral regimen are associated with in vivo synonymous mutation rates of HIV type-1 env Helene Mens Antiviral Therapy 14 Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries Martine Peeters Antiviral Therapy 14 In vivo selection by enfuvirtide of HIV type-1 env quasispecies with optimal potential for phenotypic expression of HR1 mutations Béatrice Labrosse Antiviral Therapy 14 HIV type-1 transmission dynamics in recent seroconverters: relationship with transmission of drug resistance and viral diversity Patricia RecordonPinson Antiviral Therapy 14 A phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance. Buendia P Bioinformatics Epub ahead of print Virological efficacy and emergence of drug resistance in adults on antiretroviral Johannessen A BMC Infectious Diseases - July 9 4 108 treatment in rural Tanzania. 2009 Characterization of the patterns of drug resistance mutations in newly diagnosed HIV-1 infected patients naive to the antiretroviral drugs. Alteri C BMC Infectious Diseases - July 2009 9 1 High Frequency of Clinically Significant Mutations after First-Line Generic Highly Active Antiretroviral Therapy Failure: Implications for Second-Line Options in Resource-Limited Settings N. Kumarasamy Clinical Infectious Diseases - July 2009 49 2 Antiretroviral Resistance Patterns and HIV-1 Subtype in Mother-Infant Pairs after the Administration of Combination ShortCourse Zidovudine plus Single-Dose Nevirapine for the Prevention of Motherto-Child Transmission of HIV Amphan Clinical Infectious Chalermchockcharoenkit Diseases - July 2009 49 2 High frequency of clinically significant mutations after first-line generic highly active antiretroviral therapy failure: implications for second-line options in resource-limited settings. Kumarasamv N Clinical Infectious Diseases - July 2009 49 2 Replication Capacity of HIV-1 in the Presence of Resistance-Associated Substitutions in Protease Dean L. Winslow Clinical Infectious Diseases - July 2009 49 1 High Frequency of Antiretroviral Drug Resistance among HIV-Infected Adults Receiving First-Line Highly Active Antiretroviral Therapy in N’Djamena, Chad Donato Koyalta Clinical Infectious Diseases - July 2009 49 1 HIV-1 Superinfection in an HIV-2–Infected Woman with Subsequent Control of HIV-1 Plasma Viremia Huldrych F. Günthard Clinical Infectious Diseases - June 2009 48 11 Effect of HIV-1 Subtype on Virologic and Immunologic Response to Starting Highly Active Antiretroviral Therapy Anna Maria Geretti Clinical Infectious Diseases - May 2009 48 9 Are All Subtypes Created Equal? The Effectiveness of Antiretroviral Therapy against Non–Subtype B HIV-1 Sergei L. Kosakovsky Pond Clinical Infectious Diseases - May 2009 48 9 Low Levels of Antiretroviral-Resistant HIV Infection in a Routine Clinic in Cameroon that Uses the World Health Organization (WHO) Public Health Approach to Monitor Antiretroviral Treatment and Adequacy with the WHO Recommendation for Second-Line Treatment Charles Kouanfack Clinical Infectious Diseases - May 2009 48 9 Clinical validation and applicability of different tipranavir/ritonavir genotypic scores in HIV-1 protease inhibitorexperienced patients. Saracine A Current HIV Research - July 2009 7 4 Pre-screening HIV-1 reverse transcriptase resistance mutations in subtype B patients using a novel multiplex primer extension assay. Jakobsen MR Current HIV Research - July 2009 7 4 Management of paediatric HIV-1 resistance. Gupta GB Current Opinion Infectious Diseases - June 2009 22 3 Drug-resistant viruses may repair impaired fitness by mutations outside the drug target site. Cai L Future Microbiology June 2009 4 507-9 Identification of new genotypic cut-off levels to predict the efficacy of lopinavir/ritonavir and darunavir/ritonavir in the TITAN trial. Hill A HIV Medicine Epub ahead of print The mutational archive in proviral DNA does not change during 24 months of continuous or intermittent highly active antiretroviral therapy L Palmisano HIV Medicine 10 8 Primary drug resistance and transmission analysis of HIV-1 in acute and recent drug-naïve seroconverters in Singapore CC Lee HIV Medicine 10 6 Prolonged use of tenofovir in HIV/hepatitis B virus (HBV)-coinfected individuals does not lead to HBV polymerase mutations and is associated with persistence of lamivudine HBV polymerase mutations J Audsley HIV Medicine 10 4 Drug resistant mutations detected by genotypic drug resistance testing in patients failing therapy in clade C HIV-1 infected individuals from India. Kandathil AJ Indian Journal of Medical Microbiology July 2009 27 3 Effect of human immunodeficiency virus type 1 protease inhibitor therapy and subtype on development of resistance in subtypes B and G. Palma AC Infections, Genetics and Evolution - Epub ahead of print The frequency of HIV-I drug resistance mutations among treatment-naive individuals at a tertiary care centre in south India. Kandathil AJ International 20 Journal of STD and AIDS - August 2009 8 Clinical and Genotypic Findings in HIVInfected Patients With the K65R Mutation Failing First-Line Antiretroviral Therapy in Nigeria. Hawkins CA JAIDS - Epub ahead of print Development of HIV-1 Drug Resistance Through 144 Weeks in AntiretroviralNaïve Subjects on Emtricitabine, Tenofovir Disoproxil Fumarate, and Efavirenz Compared With Lamivudine/Zidovudine and Efavirenz in Study GS-01-934. Margot NA JAIDS - Epub ahead of print Lower Risk of Resistance After ShortCourse HAART Compared With Zidovudine/Single-Dose Nevirapine Used for Prevention of HIV-1 Mother-to-Child Transmission Lehman, Dara JAIDS - August 2009 51 5 Molecular Epidemiological Study of HIV-1 CRF01_AE Transmission in Hong Kong Chen, J H K JAIDS - August 2009 51 5 Lower risk of resistance after shortcourse HAART compared with zidovudine/single-dose nevirapine used for prevention of HIV-1 mother-to-child transmission. Lehman DA JAIDS - August 2009 51 5 Initiation of HAART at Higher CD4 Cell Counts Is Associated With a Lower Frequency of Antiretroviral Drug Resistance Mutations at Virologic Failure Uy, Jonathan JAIDS - August 2009 51 4 HIV-1 Genetic Diversity and Transmitted Drug Resistance in Health Care Settings in Maputo, Mozambique Bártolo, Inês MSc JAIDS - July 2009 51 3 Increased Detection of HIV-1 Drug Resistance at Time of Diagnosis by Testing Viral DNA With a Sensitive Assay Ellis, Giovanina M JAIDS - July 2009 51 3 104 A V3-independent pathway to resistance to small molecule CCR5 inhibitors Anastasopoulou, Kleio JAIDS - June 2009 51 2 Transmission Networks of Drug Resistance Acquired in Primary/Early Stage HIV Infection BG, Brenner JAIDS - June 2009 51 2 Survival of HIV-1 Infected MultidrugResistant Patients Recycling Enfuvirtide After a Previous Failure Cossarini, Francesca JAIDS - June 2009 51 2 HIV-1 Transmission Cluster With T215D Revertant Mutation Among Newly Diagnosed Patients From the Basque Country, Spain Cuevas, Maria Teresa JAIDS - May 2009 51 1 Lack of Primary Mutations Associated With Integrase Inhibitors Among HIV-1 Subtypes B, C, and F Circulating in Brazil Passaes, Caroline Bittencourt JAIDS - May 2009 51 1 Relationship of Injection Drug Use, Antiretroviral Therapy Resistance, and Genetic Diversity in the HIV-1 pol Gene Kowalski, Jeanne JAIDS - April 2009 50 4 Prevalence of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy: evolution over 12 years and predictors Bracciale L Journal of Antimicrobial Chemotherapy Epub ahead of print Rules-based HIV-1 genotypic resistance interpretation systems predict 8 week and 24 week virological antiretroviral treatment outcome and benefit from drug potency weighting. Zazzi M Journal of Antimicrobial Chemotherapy Epub ahead of print Fosamprenavir/ritonavir in advanced HIV disease (TRIAD): a randomized study of high-dose, dual-boosted or standard dose fosamprenavir/ritonavir in HIV-1-infected patients with antiretroviral resistance Jean-Michel Molina Journal of Antimicrobial Chemotherapy 64 2 HIV-1 reverse transcriptase thumb subdomain polymorphisms associated with virological failure to nucleoside drug combinations César Garriga Journal of Antimicrobial Chemotherapy 64 2 Rapid selection and archiving of mutation E157Q in HIV-1 DNA during short-term low-level replication on a raltegravircontaining regimen Jade Ghosn Journal of Antimicrobial Chemotherapy 64 2 Using HIV resistance tests in clinical practice Stephen Taylor Journal of Antimicrobial Chemotherapy 64 2 Evolution of raltegravir resistance during therapy Nadine Sichtig Journal of Antimicrobial Chemotherapy 64 1 Rapid decline in the efficiency of HIV drug resistance genotyping from dried blood spots (DBS) and dried plasma spots (DPS) stored at 37°C and high humidity J. Gerardo GarcíaLerma Journal of Antimicrobial Chemotherapy 64 1 Virological and immunological response in HIV-1-infected patients with multiple treatment failures receiving raltegravir and optimized background therapy, ANRS CO3 Aquitaine Cohort Linda Wittkop Journal of Antimicrobial Chemotherapy 63 6 Design and validation of new genotypic tools for easy and reliable estimation of HIV tropism before using CCR5 antagonists Eva Poveda Journal of Antimicrobial Chemotherapy 63 5 Quasispecies variant dynamics during emergence of resistance to raltegravir in HIV-1-infected patients Isabelle Malet Journal of Antimicrobial Chemotherapy 63 4 Novel recombinant virus assay for measuring susceptibility of human immunodeficiency virus type 1 group M subtypes to clinically approved drugs. Covens K Journal of Clinical Microbiology July 2009 47 7 Virological response to highly active antiretroviral therapy in patients infected with human immunodeficiency virus type 2 (HIV-2) and in patients dually infected with HIV-1 and HIV-2 in the Gambia and emergence of drug-resistant variants. Jallows S Journal of Clinical Microbiology July 2009 47 7 Nevirapine Resistance in Human Immunodeficiency Virus Type 1-Positive Infants Determined Using Dried Blood Spots Stored for Up to Six Years at Room Temperature Julie A. E. Nelson Journal of Clinical Microbiology April 2009 47 4 Mutation N155H in HIV-2 integrase confers high phenotypic resistance to raltegravir and impairs replication capacity. Salgado M Journal of Clinical Virology - Epub ahead of print Detection of the protease codon 35 amino acid insertion in sequences from treatment-naïve HIV-1 subtype C infected individuals in the Central Region of Portugal. Pereira-Vaz J Journal of Clinical Virology - Epub ahead of print Mutation L33M in the HR1 region of HIV-1 gp41 may play a role in T20 resistance Huihui Chong Journal of Clinical Virology - July 2009 45 3 Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure Melanie Balduin Journal of Clinical Virology - May 2009 45 1 Resistance to antiretrovirals in HIVinfected pregnant women Adriana Weinberg Journal of Clinical Virology - May 2009 45 1 Slow Accumulation of HIV Resistance Mutations: Implications for ResourceLimited Settings? Wendy S. Stevens Journal of Infectious Diseases - September 2009 200 5 Rate of Accumulation of Thymidine Analogue Mutations in Patients Continuing to Receive Virologically Failing Regimens Containing Zidovudine or Stavudine: Implications for Antiretroviral Therapy Programs in Resource-Limited Settings Alessandro Cozzi-Lepri Journal of Infectious Diseases - September 2009 200 5 Failure of Treatment with First-Line Lopinavir Boosted with Ritonavir Can Be Explained by Novel Resistance Pathways with Protease Mutation 76V Monique Nijhuis Journal of Infectious Diseases - September 2009 200 5 Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms Soo-Yon Rhee Journal of Infectious Diseases - August 2009 200 3 Establishment of Drug-Resistant HIV-1 in Latent Reservoirs Viktor Dahl Journal of Infectious Diseases - May 2009 199 9 Identification of Nevirapine-Resistant HIV1 in the Latent Reservoir after SingleDose Nevirapine to Prevent Mother-toChild Transmission of HIV-1 Megan Wind-Rotolo Journal of Infectious Diseases - May 2009 199 9 Circulating HIV Type 1 Drug Resistance Will Have Limited Impact on the Effectiveness of Preexposure Prophylaxis among Young Women in Zimbabwe David A. M. C. van de Vijver Journal of Infectious Diseases - May 2009 199 9 Antiretroviral Drug Resistance in HIV-2: Three Amino Acid Changes Are Sufficient for Classwide Nucleoside Analogue Resistance Robert A. Smith Journal of Infectious Diseases - May 2009 199 9 Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel Dan Turner Journal of Medical Virology 81 9 The relationship between genotypic sensitivity score and treatment outcomes in late stage HIV disease after supervised HAART Delivette Castor Journal of Medical Virology 81 8 Absence of genotypic drug resistance and presence of several naturally occurring polymorphisms of human immunodeficiency virus-1 CRF06_cpx in treatment-naive patients in Estonia Radko Avi Journal of Medical Virology 81 6 Evaluation of Different RNA Extraction Methods and Storage Conditions of Dried Plasma or Blood Spots for Human Immunodeficiency Virus Type 1 RNA Quantification and PCR Amplification for Drug Resistance Testing Marjorie Monleau Journal of Medical Virology - April 2009 47 4 Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (19962008). Martinez-Cajas JL Journal of the International AIDS Society - June 2009 12 1 Sensitive detection of the K103N nonnucleoside reverse transcriptase inhibitor resistance mutation in treatment-naïve HIV-1 infected individuals by rolling circle amplification. Wang B Journal of Virological Methods - October 2009 161 1 Clinical Cut-offs for HIV-1 Phenotypic Resistance Estimates: Update Based on Recent Pivotal Clinical Trial Data and a Revised Approach to Viral Mixtures. Winters B Journal of Virological Methods - Epub ahead of print Gag Determinants of Fitness and Drug Susceptibility in Protease Inhibitor Resistant HIV-1. Parry CM Journal of Virology - Epub ahead of print Selective advantage profile of HIV-1 integrase mutants explain in vivo evolution of raltegravir resistance genotypes. Quercia R Journal of Virology - Epub ahead of print The impact of individual HIV-1 protease mutations on drug susceptibility is highly influenced by complex interactions with the background protease sequence. Van Marck H Journal of Virology - Epub ahead of print Molecular characterization of clinical isolates of human immunodeficiency virus resistant to the protease inhibitor darunavir. Saskova KG Journal of Virology 83 - September 2009 17 Positive selection pressure introduces secondary mutations at gag cleavage sites in human immunodeficiency virus type 1 harboring major protease resistance mutations. Banke S Journal of Virology 83 - September 2009 17 Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3'Azido-3'-Deoxythymidine. Delviks-Frankenberry KA Journal of Virology 83 - September 2009 17 Tissue-Specific Sequence Alterations in the Human Immunodeficiency Virus Type 1 Envelope Favoring CCR5 Usage Contribute to Persistence of Dual-Tropic Virus in the Brain Lachlan Gray Journal of Virology 83 - June 2009 11 Impact of Human Immunodeficiency Virus Type 1 Resistance to Protease Inhibitors on Evolution of Resistance to the Maturation Inhibitor Bevirimat (PA-457) Catherine S. Adamson Journal of Virology 83 - May 2009 10 Replicative Capacity Differences of Thymidine Analog Resistance Mutations in Subtype B and C Human Immunodeficiency Virus Type 1 Kimberly L. Armstrong Journal of Virology 83 - May 2009 9 Predictors of Virologic Failure and Genotypic Resistance Mutation Patterns in Thai Children Receiving NonNucleoside Reverse Transcriptase Inhibitor-Based Antiretroviral Therapy. Jittamala P Paediatric Infectious Diseases - Epub ahead of print Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use. Le T PLoS One - June 2009 4 6 HIV transmission in a state prison system, 1988-2005. Jafa K PLoS One - May 2009 4 5 Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo. Tsibris AM PLoS One - May 2009 4 5 Virological monitoring and resistance to first-line highly active antiretroviral therapy in adults infected with HIV-1 treated under WHO guidelines: a systematic review and meta-analysis Ravindra K Gupta The Lancet Infectious Diseases - July 2009 9 7