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Agenda Introduction to Biotechnology Human Health Article: “Fly genome could help improve health, environment” Biotechnology The Future of Genetics Research Imagine a dictionary… Human Genome Project Project from 1990-2003 Determining the complete DNA sequence of the human genome Interesting observations and discoveries! 2% of nucleotides in human body make up genes and code for all proteins ~25,000 total genes – much less than expected (~140,000) 50% or more of DNA is stretching and repeating sequences Bioinformatics A field of study that deals with using computer technology to create and analyze large databases of information Genomics The study of genomes and the complex interactions of genes that result in phenotypes Single Nucleotide Polymorphisms (SNPs) Can act as a marker for a gene or be associated with a gene if it is genetically linked Epigenetics The study of how changes in inheritance of certain traits or phenotypes are based on changes in gene function and not changes in DNA sequence Words changed through the ages Gene Expression and Microarrays Gene Expression Although all cells have the same DNA, some cells have specialized functions and different genes are “turned on” or expressed Microarrays Microarrays Allow scientists to see the activity of genes under certain conditions Genetics and Human Health Genetic Profile: the complete genotype of an individual, including various mutations Map Your Genome Map My Genome Product Indian Rupees Canadian Dollars Map my Genome Genetic Counselling 2,000 36.72 GenomePatri 25,000 459.05 Brainmap 8,400 154.24 Myfitgene 10,000 183.62 + Is it worth the money? + Is this a good idea? Bad idea? Genetics and Human Health How could the genetic profile be used in medicine? What may be some ethical issues? Section 6.3, p. 266 Homework “Fly genome could help improve health, environment” article and questions Your Opinion: Who do you think should have access and ownership of this sort of information? Is this sort of genetic research worth it?
