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Chemicals inside us and around us PROTEINS Proteins are a large molecules made up of one or more chains of amino acids. Amino acids are joined together by a peptide bond. Union of a few amino acids is a peptide. Chains of many amino acids is a polypeptide. Proteins that contain other kinds of molecules are called Conjugated proteins. The structures of proteins The primary structure of proteins is determinated by the sequence of amino acids. The secondary structure of proteins depends on whether the protein chains are straight or folded up in a particular pattern. Functions of proteins - Structure (i.e. myosin, keratins) - Catalysis (enzymes) - Control (insulin) - Energy (albumin, casein) - Transport (haemoglobin) - Protection (antibody) Denaturation of proteins Denaturation occurs when the normal bonding patterns are disturbed causing the change of the protein shape . This can be caused by changes in temperature, pH or salt concentration. If the protein is not severely denaturated, it may regain its normal structure. CARBOHYDRATES Carbohydrates are organic compounds and they have the general formula Cx(H2O)y. Sugars are the simplest carbohydrates. Monosaccharides Simple sugars Disaccharides Two monosaccharides linked together Oligosaccharides Few monosaccharides linked together Polysaccharides Long chains of monosaccharides Functions of carbohydrates - Intermediates for the conversion of food into energy - Energy storage molecules in plants - They form cell walls in plant cells - They are structural components in the body shells of many invertebrates - They occur in the surface coat of animal cells and in bacteria cell walls Carbohydrates are produced during photosynthesis. Photosynthesis is the process by which green plants produce carbohydrates from CO2, O2 and H20 using the energy from sunlight. LIPIDS Lipids are organic compounds that are insoluble in water but soluble in organic solvents. Simple lipids are esters of fatty acids and various alchols. Functions of lipids - Storage form for metabolic energy (triglycerides) - Components of membranes - Messagers (prostaglandis, steroid hormones) CLASSIFICATION OF LIPIDS Fat and oils Compoud lipids Waxes Esters of fatty acids and alcohols containing addictional groups ( i.e. phospholipids and glycolipids) Some important vitamins are lipids. Vitamins are substances used by living cells to aid enzyme reactions. NUCLEIC ACIDS DNA RNA (Deoxyribonucleic acid) (ribonucleic acid) DNA and RNA store and transfer genetic information DNA is the genetic material and contain the informations necessary for the synthesis of proteins. Before protein can be synthesized, the instructions in DNA must first be copied to messenger RNA. Structure and composition of nucleic acids Nucleic acids are composed of units called nucleotides linked together. Each nucleotide contains a base, a sugar (deoxyribose in DNA and ribose in RNA) and a phosphate group. DNA is composed of two strands that are twisted forming a configuration that is called double helix. THE FLOW OF GENETIC INFORMATION DNA Replication Transcription RNA Translation Proteins BIBLIOGRAPHY P. Briano – A Matter of life - English for Chemistry, Biology and Biotechnology – Edisco P. Vaudo – On the Lab – Ed. Yuvenilia D. L. Nelson, M. M. Cox – Introduzione alla Biochimica di Lehninger – Ed. Zanichelli Author: Gabriele