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Transcript
The Muscular System and
Homeostasis
10.1 Movement and Muscle Tissue
10.2 Muscles, Health, and Homeostasis
Chapter 10 The Muscular System and Homeostasis
In this chapter, you will learn:
 There are three types of muscle tissue: skeletal muscle, smooth muscle,
and cardiac muscle.
 Skeletal muscle produces body movement, maintains body
temperature, and provides support for the body.
 Muscle fibres are filled with myofibrils that house thin (actin) and
thick (myosin) contractile protein myofilaments.
 Actin and myosin slide past each other during a muscle contraction.
 Creatine phosphate, fermentation, and aerobic cellular respiration
provide energy for muscle contractions.
 Three types of skeletal muscle—slow-twitch, fast-twitch, and an
intermediate type—are found in different parts of the body.
 Muscles atrophy with inadequate stimulation and can hypertrophy
with appropriate repeated stimulation.
 The muscular system works with other body systems to maintain
homeostasis.
10.1 Movement and Muscle Tissue
In this section, you will:
 observe and compare the three types of muscle
tissue
 describe, in general, the action of actin and myosin in
muscle contraction and heat production
 identify the sources of energy for muscle contraction
Muscle Cells
Muscle Function
• Skeletal muscle supports the
body.
• Skeletal muscle makes the bones
move.
• Skeletal muscle helps to maintain
a constant body temperature.
• Skeletal muscle helps to protect
the internal organs and stabilize
the joints.
Muscle Fibres
Components of Skeletal Muscle Fibres
Component
Description
Function
Muscle fibre
single muscle cell
is responsible for muscle contractions
myoglobin
oxygen-binding pigment (similar to hemoglobin) in a skeletal
muscle fibre
stores oxygen for use during muscle
contractions
sarcolemma
membrane of a muscle fibre
surrounds the muscle fibre and
regulates the entry and exit of
materials
sarcoplasm
cytoplasm of a muscle fibre
is the site of metabolic processes for
normal cell activities; contains
myoglobin and glycogen (which
stores energy for muscle
contractions)
sarcoplasmic
reticulum
smooth endoplasmic reticulum in a muscle fibre
stores calcium ions needed for
muscle contractions
Myofibrils
organized bundles of myofilaments; cylindrical structures, as
long as the muscle fibre itself
contain myofilaments that are
responsible for muscle contractions
thick filament
fine myofilament composed of bundles of protein called
myosin (about 11 nm in diameter)
binds to actin and causes muscle
contractions
thin filament
fine myofilament composed of strands of protein called actin
(about 5 nm in diameter)
binds to myosin and causes muscle
contractions
The Movement of Actin and Myosin
Sliding Filament Model
Calcium
Controls
Muscle
Contractions
http://www.youtube.com/watch?v
=CbfK1GiaCk&playnext=1&list=PLE7E224845
4B7C3E9
animations
 http://www.youtube.com/watch?v=Y1tx8U8c670
 http://media.pearsoncmg.com/bc/bc_campbell_biolo
gy_7/media/interactivemedia/activities/load.html?49
&C
 http://www.mcgrawhill.ca/school/applets/abbio/quiz/
ch10/myofilament_contraction.swf
 http://www.mcgrawhill.ca/school/applets/abbio/quiz/
ch10/sarcomere_contraction.swf
 http://media.pearsoncmg.com/bc/bc_campbell_biolo
gy_7/media/interactivemedia/activities/load.html?49
&D
Crash Course
 https://www.youtube.com/watch?v=jqy0i1KXUO4
Big Guns: The Muscular System - CrashCourse
Biology #31
Energy for Muscle Contraction
ATP required for contraction and is generated by
THREE mechanisms.
Creatine phosphate builds up and
is stored in resting muscle (purple
box). For the muscle to contract
(green area), it needs to acquire
ATP. (A) When the muscle starts
contracting, it breaks down stored
creatine phosphate. This
generates some ATP that is used
immediately. (B) To continue
contracting, the muscle carries
out aerobic cellular respiration as
long as oxygen is available. When
the oxygen has been used up, the
muscle can carry out fermentation
for a limited period of time.
Fermentation results in only a
small amount of ATP compared
with the amount produced by
aerobic cellular respiration, and
lactate builds up. Once the
muscle resumes resting (purple
box), creatine phosphate builds
up again.
#1
Creatine Phosphate Breakdown
Creatine phosphate quickly regenerates ATP by
directly donating a phosphate (good for about 15
seconds, first ATP regeneration mechanism to kick in
under anaerobic conditions)
#2
Cellular Respiration
ATP is made in mitochondria by aerobic means - requires
oxygen.
Pyruvic acid is transported into mitochondria and oxidized to
carbon dioxide and water.
“#3
Fermentation" (glycolysis)
Anaerobic production of ATP by glycolysis occurs during
strenuous exercise after CP stores are exhausted.
Very inefficient, good for only 1-2 minutes before muscle fatigue
occurs.
The end product of glycolysis, pyruvic acid, is converted to lactic
acid if it isn't metabolized by cellular respiration fast enough to
meet ATP needs of the muscle. Lactic acid builds up, the pH
drops, muscles fatigue and ache.
Oxygen Debt
 Lactic acid is transported to the liver where it is
converted back to pyruvic acid, which is then
metabolized by cellular respiration, which of course
requires oxygen.
 The amount of oxygen required to finish
metabolism of lactic acid is the oxygen debt - that’s
the wind-sucking you do after going anaerobic.
10.2 Muscles, Health, and
Homeostasis
In this section, you will:
 explain how the skeletal muscles of the motor system
support other body systems to maintain homeostasis
 identify conditions that impair the healthy
functioning of muscles and technologies that are used
to treat or prevent these conditions
 describe the benefits of exercise for maintaining the
healthy structure and functioning of muscles
Muscular Atrophy, Sprains and Strains
A sprain is an injury to a
ligament, the tough, fibrous
tissue that connects bones to
other bone. Ligament injuries
involve a stretching or a tearing
of this tissue.
A strain is an injury to either a muscle or
a tendon, the tissue that connects
muscles to bones. Depending on the
severity of the injury, a strain may be a
simple overstretch of the muscle or
tendon, or it can result in a partial or
complete tear.
Common Disorders & Ailments of Skeletal Muscles
Condition
Description
muscular
dystrophy
a collective term for several hereditary conditions in which the skeletal muscles degenerate, lose
strength, and are gradually replaced by fatty and fi brous tissue that impedes blood circulation; this,
in turn, accelerates muscle degeneration in a fatal spiral of positive feedback
botulism
a potentially fatal muscular paralysis caused by a toxin produced by the bacterium Clostridium
botulinum; the toxin prevents the release of a muscle-stimulating compound (acetylcholine)
released by muscle-related cells of the nervous system, thus leading to paralysis
cramps
painful muscle spasms triggered by strenuous exercise, extreme cold, dehydration, salt (electrolyte)
imbalance, low blood glucose, or reduced blood fl ow
contracture
abnormal muscle shortening not caused by nerve stimulation; can result from inability to remove
calcium ions from the sarcoplasm or from the contraction of scar tissue (as in people who have
experienced severe burns)
fibromyalgia
chronic muscular pain and tenderness often associated with fatigue and sleep disturbances; can be
caused by infectious diseases, physical or emotional trauma, or medications
crush syndrome
a shock-like state following massive crushing of the muscles (as in, for example, the aftermath of an
earthquake, the collapse of a building following an explosion, or a traffi c accident); associated with
high fever, heart irregularities caused by potassium ions released from the muscles, and kidney
failure caused by blockage of the renal tubules with myoglobin released by the traumatized muscles
delayed onset
muscle soreness
pain, stiffness, and tenderness felt from several hours to a day after strenuous exercise; associated
with trauma to the muscles, disruptions in the myofibrils and sarcolemma, and increased levels of
myoglobin and muscle-fibre enzymes in the blood
myositis
muscle inflammation and weakness resulting from infection or an autoimmune disease
Myograms
These graphs show the force of
muscle contraction with time.
(A) A simple muscle twitch has
three periods: latent,
contraction, and relaxation. (B)
When a muscle is not allowed to
relax completely between
stimuli, the contraction gradually
increases in intensity until it
reaches a maximum, which is
sustained until the muscle
fatigues.
Types muscle fibres
Skeletal muscles have different proportions of fasttwitch and slow-twitch fibres. Thus, the force and
response times of their contractions differ.
Chapter 10 Review
 What body systems do muscles support?
 How do muscles support these systems?
 Explain the difference in muscle composition between
a person who is not active versus someone who is very
active?
 Describe two different types of muscle injuries.
Recommend appropriate treatments for each.
 Explain how muscles change with strength training?
With endurance training? With inactivity?
Concept Organizer
Chapter 10 Summary
 All muscles do their work by contracting (shortening). Relaxation is
the passive state of a muscle. There are three types of muscle cells:
skeletal, smooth, and cardiac.
 Skeletal muscle cells are attached to the bones of the skeleton, have
many nuclei, are striated and tubular, and contract voluntarily.
 Smooth muscle cells are found in the walls of internal organs, have
one nucleus, are not striated, and contract involuntarily.
 Cardiac muscle cells form the walls of the heart; have one nucleus,
are striated, tubular, and branched; and contract involuntarily.
 The fact that skeletal muscles can only either contract or relax means
they can pull but not push. Therefore, they must work in pairs to move
any part of the body—a relaxed muscle is only lengthened when the
opposing muscle contracts to stretch it. Skeletal muscle contractions
are explained by the sliding filament model.
Chapter 10 Summary
 Skeletal muscle produces heat as well as movement and
also supports and pads the body. Each muscle is made up
of clusters of bundles of muscle fibres, which enclose
bundles of myofibrils containing thin myofilaments of
actin and thick myofilaments of myosin. Blood vessels
supply nutrients and oxygen to the fibre bundles and
remove wastes. The oxygen fuels the cellular respiration
that supplies most of the energy muscles use.
 Nerves trigger and control muscle contractions, which last
for only a fraction of second in each muscle fibre. It is the
wave of successive contractions, or twitches, that result in a
muscle contraction. Skeletal muscles have both slow and
fast-twitch fibres that are good for either endurance (slowtwitch) or intense (fast-twitch) activities. Using the skeletal
muscles is the only way to maintain and build their
function.
Additional Videos
http://www.youtube.com/watch?v=BXOTb4ZxKDI
Extraordinary Humans: Muscles (45 min)
http://www.youtube.com/watch?v=EKWaJ_7PPXE
Science of steroids National geographic
(45 min)