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The Digestive System MEDICAL TERMINOLOGY M S . PA S T O R Nutrition and Digestion Objectives - Identify and describe the structures of the digestive using proper medical terminology - Explore careers relating to this system There are six types of nutrients: • Water • Carbohydrates • Proteins • Fats • Minerals • Vitamins Carbohydrates • Carbohydrates are the main source of energy for the body. • simple and complex carbohydrates supply glucose • fiber from plant foods helps elimination • Proteins are necessary for growth and repair of the body’s cells. – body makes 12 out of 20 amino acids – other eight essential amino acids come from food • Fats provide energy and key building components. – fats are saturated and unsaturated – butter, lard and oils – essential fatty acids come from food • Minerals are inorganic materials needed in small amounts – help to build or repair tissues – replenished by eating variety of foods • Vitamins are organic molecules that work with enzymes. – vitamins are fat-soluble and water-soluble – Fat soluble: A, D, E, K – Water-soluble: B, C (ascorbic acid) , folic acid – regulate cell functions, growth, development • Unbalanced diets can lead to malnutrition or undernutrition – Malnutrition occurs in when you don’t get the right nutrients for your body, or you over consume some nutrients. – Undernutrition is when you lack the essential nutrients your body needs in order to function properly. Key Concept #2 The main stages of food processing are ingestion, digestion, absorption, and elimination • Ingestion is the act of eating • Digestion is the process of breaking food down into molecules small enough to absorb • Absorption is uptake of nutrients by body cells • Elimination is the passage of undigested material out of the digestive compartment LE 41-12 Small molecules Pieces of food Mechanical digestion Chemical digestion Nutrient (enzymatic hydrolysis) molecules enter body cells Undigested material Food INGESTION DIGESTION ABSORPTION ELIMINATION • More complex animals have a digestive tube with two openings, a mouth and an anus – This digestive tube is called a complete digestive tract or an alimentary canal – It can have specialized regions that carry out digestion and absorption in a stepwise fashion Key Concept #3 Each organ of the mammalian digestive system has specialized food-processing functions • The human digestive system consists of an alimentary canal and accessory glands that secrete digestive juices through ducts • Accessory glands are the – salivary glands – pancreas – liver – gallbladder • Food is pushed along by peristalsis, rhythmic contractions of muscles in the wall of the canal LE 41-15a Cardiac orifice Tongue Salivary glands Oral cavity Parotid gland Sublingual gland Pharynx Esophagus Submandibular gland Pyloric sphincter Liver Stomach Ascending portion of large intestine Gallbladder Pancreas Ileum of small intestine Small intestine Large intestine Rectum Anus Appendix Cecum Duodenum of small intestine The Oral Cavity, Pharynx, and Esophagus • In the oral cavity, food is lubricated and digestion begins • Teeth chew food into smaller particles that are exposed to salivary amylase, initiating breakdown of carbohydrates • The region we call our throat is the pharynx, a junction that opens to both the esophagus and the windpipe (trachea) • The esophagus pushes food from the pharynx down to the stomach by peristalsis Bolus of food Tongue Epiglottis up Epiglottis up Pharynx Glottis Larynx Trachea Glottis down and open Esophageal sphincter contracted Epiglottis down Esophagus Glottis up and closed Esophageal sphincter relaxed Esophageal sphincter contracted Relaxed muscles To lungs To stomach Contracted muscles Relaxed muscles Stomach The Stomach • The stomach stores food and secretes gastric juice, which converts a meal to acid chyme • Gastric juice is made up of hydrochloric acid and the enzyme pepsin • Pepsin is secreted as inactive pepsinogen by chief cells; pepsin is activated when mixed with hydrochloric acid in the stomach – It’s purpose is to break down protein • Mucus protects the stomach lining from gastric juice Esophagus Cardiac orifice Stomach 5 µm Pyloric sphincter Interior surface of stomach Small intestine Folds of epithelial tissue Epithelium Pepsinogen Pepsin (active enzyme) HCl Gastric gland HCl converts pepsinogen to pepsin. Pepsin then activates more pepsinogen, starting a chain reaction. Pepsin begins the chemical digestion of proteins. Mucus cells Chief cells Parietal cells Pepsinogen and HCl are secreted into the lumsden of the stomach. Chief cell Parietal cell • Gastric ulcers, lesions in the lining, are caused mainly by the bacterium Helicobacter pylori Bacteria 1 µm Mucus layer of stomach The Small Intestine • The small intestine is the longest section of the alimentary canal • It is the major organ of digestion and absorption • The first portion of the small intestine is the duodenum – Where acid chyme from the stomach mixes with digestive juices from the pancreas, liver, gallbladder, and the small intestine itself Accessory Glands Liver Bile Gallbladder Stomach Acid chyme Intestinal juice Pancreas Duodenum of small intestine The Pancreas • The pancreas has both digestive and endocrine (hormone) functions. • Digestive Function – Releases bicarbonate to neutralize the acid chyme that enters the small intestine – Releases proteases to help with further digestion of proteins • Endocrine Function – Releases insulin & glucagon to control bloodsugar levels The Liver • The liver produces bile, which aids in digestion and absorption of fats The Small Intestine: Absorption of Nutrients • The small intestine has a large surface area, due to villi and microvilli that are exposed to the intestinal lumen • The enormous microvillar surface greatly increases the rate of nutrient absorption Key Vein carrying blood to hepatic portal vessel Nutrient absorption Microvilli (brush border) Blood capillaries Epithelial cells Muscle layers Epithelial cells Large circular folds Villi Lacteal Villi Intestinal wall Lymph vessel The Large Intestine • The large intestine, or colon, is connected to the small intestine • Its major function is to recover water that has entered the alimentary canal • Wastes of the digestive tract, the feces, become more solid as they move through the colon • Feces is stored in the rectum until it exits via the anus Glucose Regulation as an Example of Homeostasis • Animals store excess calories as glycogen in the liver and fats in the muscles. • Hormones like insulin & glucagon regulate glucose metabolism • When fewer calories are taken in than are expended, fuel is taken from storage and broken down to be used by cells. LE 41-3 STIMULUS: Blood glucose level rises after eating. Homeostasis: 90 mg glucose/ 100 mL blood STIMULUS: Blood glucose level drops below set point.