Download January 7, 2005 - Expert Witness Network

Frank E. Barber, Ph.D.
4003 Pintail Cove
Oxford Mississippi 38655
662-236-4226
[email protected]
Education
1976 Ph.D. University of Washington, Seattle, WA, Electrical & Biomedical Engineering.
Major area of study: Electromagnetic Fields and Waves. Dissertation: "Ultrasonic Microprobe:
for modeling and measuring the angle distribution of echoes from diseased arterial tissues"
1969 M.S. Northeastern University, Electrical Engineering
1966 A.B. Dartmouth College
Honors and Awards
1982 Distinguished Lecturer, IEEE Group on Sonics and Ultrasonics
1980 Research Career Development Award, National Cancer Institute, National Institutes of
Health
1975 Sigma Xi
1975 Tau Beta Pi
Professional Experience
April 2004 to present Senior Scientist for Biomedical Acoustics, National Center for Physical
Acoustics, University of Mississippi, Oxford, MS.
June 1994 to May 2004 President and General Manager, Sound Products International, Inc.,
Brattleboro VT; owned and operated a small company.
June, 1991 - June 1994 Senior Technology Analyst, Pfizer, Inc., Medical Devices Division,
Hospital Products Group, New York, N.Y.
 For Pfizer Corporate Headquarters: monitored research technology & management,
and new product acquisition & development for Pfizer and its Medical Devices
subsidiary companies:
Valleylab, Boulder CO - electrosurgical instruments, ultrasonic surgery, minimally
invasive surgery
Schneider Labs., Minneapolis MN - Catheters & stents for cardiac angiography and
angioplasty
American Medical Systems, Minneapolis MN - Urological devices, prostheses,
prostate surgery
Strato Medical (&Infusaid) Beverly, MA - Implantable pumps, infusion ports,
vascular access devices
81955913 8/11/2017 1:46 AM Page 1 of 6


Howmedica, E. Rutherford, NJ - Hip and knee prostheses, fixation devices,
maxillofacial implants
Biomedical Sensors (England) - in-vivo blood gas sensors
Advisor to and technical liaison between Pfizer and subsidiary Shiley, Inc. regarding
research program to minimize the problems associated with Shiley's heart valve
malfunction
Developed technology analysis and transfer program between Pfizer and David Sarnoff
Research Center, Princeton, NJ, in areas of optics and electro-optics, and
micromachine and nanomachine technology.
April, 1990 - June, 1991 Director, Research & Engineering, Life Sciences, Inc., West Lebanon
NH
1987-April, 1990 Senior Scientist, Institute of Applied Physiology & Medicine, Seattle, WA;
and;
1989-1990 Affiliate Associate Professor of Electrical Engineering, University of Washington,
Seattle
 Ultrasound imaging and tissue characterization
 Clinical research: contrast venography & duplex ultrasound for deep venous
thrombosis.
1975-1987
Harvard Medical School, Department of Radiology; with staff appointments at the
Brigham and Women's Hospital and the Dana Farber Cancer Institute, Boston, MA
1980-1987 Assistant Professor of Radiology (Physics)
1977-1980 Instructor in Radiology (Physics)
1975-1977 Associate in Radiology (Physics)
 Founded & directed Harvard Medical School's Ultrasound Physics Program
 Conceived and developed the Scanning Acoustic Microprobe (SCAMP) - unique echo
sampling and Fourier reconstruction methods for imaging fine scale tissue structure
 Recipient of major National Cancer Institute grants for ultrasonic characterization of
normal and diseased tissues in breast cancer
 Recipient of major National Heart Lung & Blood Institute contracts for ultrasonic
detection and characterization of atherosclerotic lesions
 Collaborated in clinical research: hyperthermia, cardiology and cardiovascular disease,
cancer
 Taught in both medical, and physics and engineering curricula, and supervised
graduate students at Harvard and MIT. Initiated and directed the physics portion of a
National Cancer Institute training program in imaging methods in cancer.
1984-1985 Division of Ultrasound, Elscint Inc., Boston MA-on leave of absence from Harvard
May 1984 - Dec. 1984 Senior Scientist and Director, Probe Division
Jan. 1985 - Apr. 1985 Director of R & D
Responsible for new product research and development
 new production prototypes, manufacturing methods; production & quality control
planning
81955913 8/11/2017 1:46 AM Page 2 of 6

phased and linear array transducers; protocols and procedures for FDA regulatory
compliance
 pulse-Doppler, duplex instruments for vascular and cardiovascular diagnosis
Assisted with the return of Elscint Ultrasound from Boston to Haifa and Jerusalem, Israel.
1970-1975 Engineer, Center for Bioengineering, Univ. of Washington, Seattle, WA
 Conceived, designed and developed for clinical use the first Duplex pulse-echo, pulseDoppler systems for ultrasonic diagnosis - coined the term "Duplex Ultrasound"
 Principal Investigator for all imaging and duplex Doppler projects for the
Cardiovascular Instrumentation Research and Development Program, National Heart,
Lung and Blood Institute.
 Created the ultrasound imaging system that directly elevated ultrasonography from a
clinical research tool to the status of accepted medical practice
 Developed computer methods for three dimensional mapping of ultrasonic images of
the heart
 Performed and published the first measurements to characterize acoustic scattering
from atherosclerotic plaque.
1966-1970 Staff Associate, Bioengineering Department, Forsyth Dental Institute, Boston, MA
With Dr. Sidney Lees, founded the first Bioengineering Program in dental
research
 Developed ultra-high resolution ultrasound transducers for non-destructive testing
 First to produce accurate measurements of the ultrasonic properties of hard dental
tissues.
1965 (Summer) Research Assistant, Radio-physics Department, Dartmouth College.
Military:
1960-1963 - U.S. Army, Honorable discharge.
Consulting Assignments
Advanced Technology Laboratories, Inc., Seattle WA
A.D. Little Company, Inc., Cambridge MA
Technicare Ultrasound, Denver CO
Johnson & Johnson Company NJ
Recurrent Solutions, Inc., Cambridge MA
National Cancer Institute
National Heart Lung & Blood Institute
Elscint, Inc., Boston MA & Haifa Israel
Gordon Products, Inc., Groton CT
Institute of Applied Physiology and Medicine, Seattle WA
New York Institute of Technology, New York NY
SRI International (Stanford Research Institute), Menlo Park, CA
Palo Alto Research Center (PARC), Xerox Corp, Palo Alto, CA
Law Firm of Weil, Gotshal & Manges, New York NY
Law Firm of Allen Rubenstein, New York NY
81955913 8/11/2017 1:46 AM Page 3 of 6
National Science Foundation, Bethesda MD
Continental Can Company, Chicago IL
Whitaker Foundation, Boston MA
Children's Hospital Medical Center, Boston MA
NTR Systems, Inc., Seattle WA
Dentron, Inc., Lincoln NB
Law Firm of Costello and Mabie, Brattleboro VT
Pfizer Inc., Hospital Products Group, New York NY
Professional Activities & Affiliations (memberships & various offices held)
American Association of Physicists in Medicine
Association for the Advancement of Medical Instrumentation
Consultant Editor, Medical Ultrasound.
Acoustical Society of America
American Institute of Ultrasound in Medicine
Institute of Electrical and Electronics Engineers
Engineering in Medicine and Biology Society
Ultrasonics, Ferroelectrics and Frequency Control Society
Selected Bibliography
1. Lees S, Barber FE. Looking into teeth with ultrasound. Science. August 1968; 161:477-478.
2. Barber FE, Baker DW, Nation AWC, Strandness DE Jr., Reid JM. Ultrasonic duplex echoDoppler scanner. IEEE Trans. Bio-Medical Engineering, March 1974; BME-21, 2:109-113.
3. Barber FE, Baker DW, Strandness DE Jr, Ofstad JM, Mahler GD. Duplex Scanner II: for
simultaneous imaging of artery tissues and flow. 1974 Ultrasonics Symposium Proceedings,
IEEE Press, 1974; 744-748.
4. Barber FE. Development of instrument for non-invasive detection of atherosclerotic lesions.
NHLBI Devices and Technology Branch Contractors Conf. Proc., Bethesda MD, p.151, Dec.
1976.
5. Felix WR, Barber FE, Silverman A, Segal B, O'Hara J. Measurement of arterial blood flow
using duplex Doppler ultrasound & sound spectral analysis. Proc. Symp. on Hemodynamics of
Blood 1979, pp. 71-77.
6. Reuter KL, D'Orsi CJ, Raptopoulow VD, Barber FE, Moss LJ. Sono-graphic pseudoasymmetry of the prenatal cerebral hemispheres, 26th Annual Convention of the AIUM, San
Francisco, CA, August 1981.
7. Barber FE, Griffice CP. Power deposition for ultrasound hyperthermia. In: Nussbaum GH.
ed., Physical Aspects of Hyperthermia, American Institute of Physics, New York, 1982:209-230.
81955913 8/11/2017 1:46 AM Page 4 of 6
8. Patriquin HB, DiPietro M, Barber FE, Teele RL. Sonography of thickened gallbladder wall:
Causes in Children. Am. J. Radiology 1983; 141:57-60.
9. Klepper, JR, Barber FE, and Spencer MP. Improved instrumentation for the diagnosis of
venous thrombosis. Presented at the Devices and Technology Branch Contractors Meeting,
Bethesda, MD, December 5-7, 1988.
10. Barber, FE. The Scanning Acoustic Microprobe: I. Analysis and synthesis of a spherically
symmetric point spread function; and II. Application to the measurement and characterization of
a piston reflector. J. Acous. Soc. Am. January, 1991.
11. Barber, FE and X Yang, Real-time detection of HIFU-induced changes in focal attenuation
from B-mode compound scan data. Prog. & Abstracts, 5th Intl. Symp. on Therapeutic
Ultrasound, Oct. 27-29, Boston, MA.
12. Yang, X, Barber FE, and Church CC, The activation of tissue factors by high intensity
focused ultrasound-a pathway to acoustic-biochemical hemostasis. Prog. & Abstracts, 5th Intl.
Symp. on Therapeutic Ultrasound, Oct. 27-29, Boston, MA.
Teaching Experience & Principal Invited Lectureships
Brigham and Women's Hospital, Boston
Harvard School of Public Health, Boston
Harvard-MIT Program in Health Sciences and Technology, Boston
Harvard Medical School, Boston
Northeastern University, Department of Electrical Engineering, Boston
Massachusetts Institute of Technology, Department of Electrical Engineering, Cambridge
Boston University, Department of Biomedical Engineering, Boston
American Association for the Advancement of Science
American Association of Physicists in Medicine
New England Roentgen Ray Society
Atherosclerosis Research Center, MIT & Mass. General Hospital
Children's Hospital Medical Center, Boston
Latin American Radiological Society
Indianapolis Center for Advanced Research
International Conf. on Information Processing in Medical Imaging, Stanford U., Palo Alto,
CA
New England Deaconess Hospital, Boston
Hewlett Packard Co., Palo Alto, CA
SRI International (Stanford Research Institute), Menlo Park, CA
Varian Associates, Palo Alto, CA
IBM, Thomas J. Watson Laboratories, Yorktown Heights, NY
Philips Laboratories, Briarcliff Manor, NY
Sigma Xi Society
Pennsylvania State University
81955913 8/11/2017 1:46 AM Page 5 of 6
Washington University, St. Louis, MO
Marquette University, Milwaukee WI
American Society for Nondestructive Testing
Institute of Electrical & Electronics Engineers:
Ultrasonics Ferroelectrics and Frequency Control Society
Engineering in Medicine & Biology Society
National Cancer Institute's Training Program in Imaging Methods in Cancer
University of Louisiana, Lafayette
81955913 8/11/2017 1:46 AM Page 6 of 6