Download Ab to glomerular basement membrane

Glomerular basement membrane antibodies
General Information
Diagnostic test for Goodpasture’s syndrome.
•
Specimen transport: At room temperature
•
Repeat Frequency
•
Special precautions
Laboratory Information
Normal Range
Volume and Sample type
Method
Turnaround time
(working days)
< 10 units
7ml clotted blood
ELISA
7 days
Clinical Information
•
Indications for the test:
Rapidly progressive glomerulonephritis.
•
Factors affecting the test
In comparison to biopsy proven cases of GBM disease, ELISA tests for anti-GBM
antibodies have been shown to have a clinical diagnosis agreement of 97 percent, a
sensitivity of 87 percent and a specificity of 98 percent. A small number of patients
with other renal diseases - systemic vasculitis, SLE and mixed connective tissue
disease may exhibit borderline titres.
Clinical workstation reference: GBM Ab to glomerular basement membrane (GBM)
8