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5.3 Regulation of the Cell Cycle
Internal and external factors regulate cell division.
• External factors include physical and chemical signals.
• Growth factors are proteins that stimulate cell division.
– Most mammal cells form a single layer in a culture
dish and stop dividing once they touch other cells.
13.1 Ecologists Study Relationships
BellWORK!!!! Do it now.
What is it called when some cells in your
body won’t stop dividing (mitosis).
Hint: it kills 12% of humans worldwide.
5.3 Regulation of the Cell Cycle
CANCER
•
when cells divide and grow uncontrollably, forming
tumors and invading the body.
5.3 Regulation of the Cell Cycle
• Apoptosis is when cells die automatically/normally
5.3 Regulation of the Cell Cycle
Cell division is uncontrolled in cancer.
• When cancer cells enter the blood, it spreads
through the body (metastacizes). This is VERY
bad.
normal cell
cancer cell
bloodstream
5.3 Regulation of the Cell Cycle
Symptoms
• Vary widely
• “The Great Imitator”
5.3 Regulation of the Cell Cycle
Tumors are lumps of cancer cells
• Two Types
1. Benign tumors remain
clustered and can be
removed.
2. Malignant tumors
metastasize (spread)
5.3 Regulation of the Cell Cycle
• About half of people who get treatment for malignant cancer
die from it
5.3 Regulation of the Cell Cycle
• What causes cancer?
• causes of cancer are diverse, complex, and only partially
understood.
• Things known to increase risk (carcinogens):
• Tobacco use
• Radiation
• Laziness
• Obesity
• Pollution
• The Sun
5.3 Regulation of the Cell Cycle
How to avoid cancer:
•
•
•
•
•
Don’t smoke cigarettes
Don’t drink alcohol
Exercise 3-5 times per week
Eat vegetables, fruit, and fish
Avoid red meat (cows)
5.3 Regulation of the Cell Cycle
Curing Cancer
• Cancer is a class of diseases
– There will probably never be one “cure”
• We still do not know:
– What, exactly, causes cells to become cancerous?
– How, exactly, do cancer cells work?
• Focus on prevention.
• So, be a doctor, and help figure it out!