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Download Profil de poste Postdoc bioinformatique UMR1011
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Post-doctoral position at INSERM UMR1011-Lille Transcriptional regulation by nuclear receptors in obesity-related diseases Research project: Our laboratory, which is part of the European Genomic Institute for Diabetes (EGID, Lille, France), studies obesity-related diseases including diabetes and nonalcoholic fatty liver disease. We rely on long-lasting experiences in biochemistry, molecular biology and functional genomics together with access to state-of-the-art technologies to investigate transcriptional regulatory programs involving nuclear receptors in key metabolic organs (liver, adipose tissue…). Using a combination of in-vitro cellular and animal models, we aim to define the role exerted by nuclear receptors in the pathophysiology of these obesityrelated diseases. Candidate profile: We are seeking a highly motivated post-doc who should have a PhD in molecular biology with backgrounds in the study of transcriptional regulation. His/her project will involve investigation of transcriptional regulatory networks and epigenome using both cell-lines and mouse tissues. Experience and interest for analyses of genomic data issued from high-throughput sequencing technologies or microarrays would be a strong asset. Indeed, in close interaction with both bioinformaticians and biologists from our laboratory, the successful candidate will leverage omics data in order to identify novel regulatory pathways involving nuclear receptors in obesity-related diseases. For further details visit our website (http://www.u1011.lille.inserm.fr/) and contact Drs J. Eeckhoute ([email protected]) [email protected]). or P. Lefebvre (philippe-
