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C. elegans model of Duchenne muscular dystrophy: analysis of muscle structure (optic microscopy) active molecule phalloidin staining: visualization of actine fibers WT dys-1-; CeMyoDts dys-1-; CeMyoDts + prednisone (0.5 mg/ml / steroid) Identification of prednisone from a test screen of 100 molecules (reduces muscle degeneration) Prednisone is used as a treatment for DMD boys Identification of this molecule in the C. elegans model in a blind screen indicates that this model can be used for the search of active molecules
