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Chapter 1: The Nature of Analytical Chemistry CHE 321: Quantitative Chemical Analysis Dr. Jerome Williams, Ph.D. Saint Leo University Overview • Role of Analytical Chemistry • Quantitative Analytical Methods Role of Analytical Chemistry • “Analytical chemistry is a measurement science consisting of a set of powerful ideas and methods that are useful in all fields of science and medicine.” Role of Analytical Chemistry • Terminology – 1. Qualitative Analysis – reveals identity of elements and compounds in a sample. – 2. Quantitative Analysis – determines identity of species (if unknown) and the amount of each substance in a sample. Role of Analytical Chemistry • Terminology (continued) – 3. Analyte – components of a sample that are to be determined. Role of Analytical Chemistry • Analytical chemists use science and technology to solve practical problems. • Analytical chemistry is applied in all areas of science, industry, and medicine. • Chemistry: The Central Science; all sub-disciplines rely on analytical chemistry to function. Figure 1-1 p3 p6 Quantitative Analytical Methods • Four general areas of analysis – 1. Gravimetric methods determine the mass of analyte or some compound chemically related to it. – 2. Volumetric methods use the volume of a solution containing sufficient reagent to react with the analyte. Quantitative Analytical Methods • Four general areas of analysis – 3. Electrochemical methods measure electrical properties (potential, current, resistance) to find composition of samples. – 4. Spectroscopic methods based on interaction of electromagnetic radiation with analyte atoms & molecules, or on the production of radiation by analytes.