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7
The Nervous System
PART A
PowerPoint® Lecture Slide Presentation by Jerry L. Cook, Sam Houston University
ESSENTIALS
OF HUMAN
ANATOMY
& PHYSIOLOGY
EIGHTH EDITION
ELAINE N. MARIEB
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Neurons
 Neurons = nerve cells….NOT NERVES!
 transmit messages
 Major regions of neurons
 Cell body – nucleus and metabolism
 Processes – fibers extending from the cell
body
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Anatomy
 Cell body
 Processes of cell body
 Dendrites –
conduct impulses
toward the cell
body (incoming)
 Axons – conduct
impulses away
from the cell body
(outgoing)
Figure 7.4a–b
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Axons and Nerve Impulses
 Axons end in axonal terminals
 Axonal terminals contain vesicles with
neurotransmitters
 Axonal terminals are separated from the next
neuron by a gap (synaptic cleft)
 *Synapse – junction between nerves
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
How Neurons Communicate at Synapses
Figure 7.10
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Fiber Coverings
 Schwann cells –
produce myelin
sheaths in jelly-roll
like fashion
 Nodes of Ranvier –
gaps in myelin sheath
along the axon
Figure 7.5
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Component Location
 Gray matter – cell bodies and unmyelinated
fibers
 Areas where signals are processed
 Cortex of brain
 Center of spinal cord
 White matter – myelinated axons
 Areas where signals are transmitted
 Center of brain
 Outer area of spinal cord
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Classification of Neurons
 Sensory neurons
 Carry impulses from the sensory receptors
to CNS
 Motor neurons
 Carry impulses from CNS
 Interneurons
 Connect sensory and motor neurons in the
CNS
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Neuron Classification
Figure 7.6
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
(Neuroglia)
 Astrocytes
 Abundant, star-shaped cells
 Brace neurons
 Form barrier
between capillaries
and neurons
 Control the chemical
environment of
the brain
Figure 7.3a
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Microglia
 Spider-like phagocytes
 Dispose of debris
 Ependymal cells
 Line cavities of the
brain and spinal cord
 Circulate
cerebrospinal
fluid
Figure 7.3b–c
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Oligodendrocytes
 Produce myelin sheath around nerve fibers
in the central nervous system
Figure 7.3d
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nervous Tissue: Support Cells
 Satellite cells
 Protect neuron cell bodies
 Schwann cells
 Form myelin sheath in the peripheral
nervous system
Figure 7.3e
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Functional Properties of Neurons
 Irritability – ability to respond to stimuli
 Conductivity – ability to transmit an impulse
 The plasma membrane at rest is polarized
 Fewer positive ions are inside the cell than
outside the cell
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Starting a Nerve Impulse
 Depolarization – a
stimulus depolarizes the
neuron’s membrane
 A depoloarized
membrane allows
sodium (Na+) to flow
inside the membrane
 The exchange of ions
initiates an action
potential in the neuron
Figure 7.9a–c
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Nerve Impulse Propagation
 The impulse
continues to move
toward the cell body
 Impulses travel faster
when fibers have a
myelin sheath
Figure 7.9d–f
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
The Action Potential
 If the action potential (nerve impulse) starts,
it continues over the entire axon
 Potassium ions rush out of the neuron after
sodium ions rush in, which repolarizes the
membrane
 The sodium-potassium pump restores the
original configuration
 This action requires ATP
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
Continuation of the Nerve Impulse
between Neurons
 Impulses can cross the synapse to another nerve
 Neurotransmitter is released from the axon
terminal
 Dendrite on next neuron has receptors that
are stimulated by the neurotransmitter
 An action potential is started in the dendrite
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
How Neurons Communicate at Synapses
Figure 7.10
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings