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7 The Nervous System PART A PowerPoint® Lecture Slide Presentation by Jerry L. Cook, Sam Houston University ESSENTIALS OF HUMAN ANATOMY & PHYSIOLOGY EIGHTH EDITION ELAINE N. MARIEB Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Neurons  Neurons = nerve cells….NOT NERVES!  transmit messages  Major regions of neurons  Cell body – nucleus and metabolism  Processes – fibers extending from the cell body Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Neuron Anatomy  Cell body  Processes of cell body  Dendrites – conduct impulses toward the cell body (incoming)  Axons – conduct impulses away from the cell body (outgoing) Figure 7.4a–b Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Axons and Nerve Impulses  Axons end in axonal terminals  Axonal terminals contain vesicles with neurotransmitters  Axonal terminals are separated from the next neuron by a gap (synaptic cleft)  *Synapse – junction between nerves Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings How Neurons Communicate at Synapses Figure 7.10 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Fiber Coverings  Schwann cells – produce myelin sheaths in jelly-roll like fashion  Nodes of Ranvier – gaps in myelin sheath along the axon Figure 7.5 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Neuron Component Location  Gray matter – cell bodies and unmyelinated fibers  Areas where signals are processed  Cortex of brain  Center of spinal cord  White matter – myelinated axons  Areas where signals are transmitted  Center of brain  Outer area of spinal cord Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Functional Classification of Neurons  Sensory neurons  Carry impulses from the sensory receptors to CNS  Motor neurons  Carry impulses from CNS  Interneurons  Connect sensory and motor neurons in the CNS Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Neuron Classification Figure 7.6 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells (Neuroglia)  Astrocytes  Abundant, star-shaped cells  Brace neurons  Form barrier between capillaries and neurons  Control the chemical environment of the brain Figure 7.3a Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Microglia  Spider-like phagocytes  Dispose of debris  Ependymal cells  Line cavities of the brain and spinal cord  Circulate cerebrospinal fluid Figure 7.3b–c Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Oligodendrocytes  Produce myelin sheath around nerve fibers in the central nervous system Figure 7.3d Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nervous Tissue: Support Cells  Satellite cells  Protect neuron cell bodies  Schwann cells  Form myelin sheath in the peripheral nervous system Figure 7.3e Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Functional Properties of Neurons  Irritability – ability to respond to stimuli  Conductivity – ability to transmit an impulse  The plasma membrane at rest is polarized  Fewer positive ions are inside the cell than outside the cell Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Starting a Nerve Impulse  Depolarization – a stimulus depolarizes the neuron’s membrane  A depoloarized membrane allows sodium (Na+) to flow inside the membrane  The exchange of ions initiates an action potential in the neuron Figure 7.9a–c Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Nerve Impulse Propagation  The impulse continues to move toward the cell body  Impulses travel faster when fibers have a myelin sheath Figure 7.9d–f Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings The Action Potential  If the action potential (nerve impulse) starts, it continues over the entire axon  Potassium ions rush out of the neuron after sodium ions rush in, which repolarizes the membrane  The sodium-potassium pump restores the original configuration  This action requires ATP Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Continuation of the Nerve Impulse between Neurons  Impulses can cross the synapse to another nerve  Neurotransmitter is released from the axon terminal  Dendrite on next neuron has receptors that are stimulated by the neurotransmitter  An action potential is started in the dendrite Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings How Neurons Communicate at Synapses Figure 7.10 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings