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Expert Reviews Project CARTHER Excellence: Strengths: This is a highly innovative project which relies on carbon based fluorescent nanomaterials as markers of cancerous cells for diagnostics and therapy. The multidiscipliarity nature of the proposed research has been demonstrated as it involves advanced knowledge in physics, chemistry, biology and nanomaterials. Knowledge sharing among the participants in light of the research and innovation objectives is clearly described and the expertise, contribution, and complementarity of each partner are identified. The exchange programme is suitable and consists of training courses, industry - academia secondments, common research activities, regular meetings and internal workshops. Weaknesses: The main objective of the experimental study is defined only in a generic manner. There is not a critical discussion as to why four different types of nanomaterials should be investigated. The current state of the art has not been thoroughly reviewed. Impact Strengths: The project contribution to realising the potential of individuals and to providing new skills and career perspectives in the fields of nanomaterials, bio-imaging and cancer therapy is high. The researchers will gain experience in a multi-disciplinary academic and industrial environment. The potential impact on competitiveness and innovation in the field of bio-functionalised nanomaterials at the European and global levels is convincing, in particular in reducing healthcare costs and in developing cutting edge technologies in nanomaterial synthesis, characterisation, and bio-imaging. The measures proposed for dissemination and communication, including public engagement, are convincing and clearly described. IPR issues and exploitation of the potential project results by the private sector and academia are adequately addressed. Weaknesses: No clear provisions are made for the organisation of an international workshop towards the end of the project. Implementation Strengths: The project work plan is coherent and structured into work packages consistent with the overall project objectives. Milestones and deliverables are adequate to monitor the intermediate targets and long-term objectives. The allocation of resources for the different work packages is appropriate. The proposed management, including quality management, and coordination structure for the project are clearly described. The participating institutions have the required infrastructure and experimental resources required to carry out the proposed project. The competences, experience and complementarity of the participating organisations and institutional commitment are clearly described. Weaknesses: The risks that might endanger the scientific project objectives are not sufficiently addressed and the measures to mitigate such risks are not clear. This is particularly important in this research project as it is based on relatively new ideas and developments. The description of what will be done in each work package is not sufficiently detailed. Project CARDIALLY Excellence Strengths: The proposal is innovation driven and of scientific relevance. The research proposed is of high quality and the methodology is appropriate. The scientific expertise of the partners is very relevant to the proposal, as demonstrated from their scientific publications. The applicants describe in a credible way the quality and benefits of their interactions within the consortium. Partners are highly complementary, and their roles are well distributed. Weaknesses: The actions for knowledge transfer are broadly addressed, and not specific to the innovation objectives of the proposal Impact Strengths: The benefits for individuals in relation to career perspectives, skills and working conditions are properly and convincingly addressed. The applicants describe in a credible way the measures to achieve a long-lasting and strong partnership. Outreach activities are very well addressed. Weaknesses There are no major weaknesses detected on impact in the proposal. Implementation Strengths: The work plan is excellent. The technical tasks propose high quality research in a proper timeframe. The management structures are very well articulated. The infrastructure available is suitable for the proposed work. The competences and experience of the various partners are highly relevant. There are clear complementarities among the partners. Weaknesses: The risk analysis is broadly presented, and not specific to the work proposed. Project MAKERS Excellence Strengths: The research is credible with multidisciplinary character and clearly stated objectives. The project credibly suggests generating a set of recommendations for an improvement of the EU industrial policy based on novel research. The proposed research methodology is adequate and is very well described. The project gives sufficient details about the mechanism of interaction among partners and the potential for achievement of synergy effect. Weaknesses: The presentation of the sharing of knowledge lacks some details regarding the planned activities. The project does not give full description of how the economic sectors were selected. Impact Strengths: The participating institutions have demonstrated that they will provide good working conditions. The project offers very good opportunities for career development and skills improvement for all researchers. The project offers suitable opportunities for an efficient communication of the study’s findings. The mechanism for transfer of knowledge among the participants is adequately presented and there is convincing evidence about the benefits for the involved institutions and globally Weaknesses The future collaboration is not sufficiently described to fully convince about sustainability beyond EU funding. The project does not explain sufficiently the division of responsibilities among partners for the dissemination of the project's outcome. Implementation Strengths: The work plan is structured adequately. The allocation of tasks and resources is appropriate and is well matched with competences of partners. The institutional environment is suitable for the successful execution of the project. The project presents strong institutional commitments Weaknesses: The proposed management structure is insufficiently detailed. The institutional complementarity is not sufficiently described in the proposal. Project REDOXIT Excellence Strengths: The research objectives of the project are clear. The proposal exploits recent developments in all partners and seeks to capitalise on these by bringing together analytical science, cell biology, animal models and drug development. The proposed experimental work is well supported by citations and preliminary work reported by the applicants and has a very high quality. This is a timely and innovative multi-disciplinary proposal to develop fundamental understanding of a potentially very interesting therapeutic target. The quality of knowledge sharing among the participants in light of the research objectives is very good Weaknesses: The type of the interaction between the participating organizations is not well addressed. The experience of each participant, what exactly would be transferred per secondments and examples of knowledge return is not convincingly presented. Progress beyond the state of the art is not clearly spelled out. Impact Strengths: The potential of enhancing research- and innovation-related human resources is high and is convincing from the concrete examples that were presented. The effectiveness of the proposed measures for communication and results dissemination is well presented and is very good. There are some project-specific and concrete examples, being workshops one of them. The development of new and lasting research collaborations is sufficiently presented and these are sound. There are some concrete examples of potential new collaboration and the proposal well addresses their self-sustainability beyond the lifetime of the project. Weaknesses: The potential contribution to the improvement of the research and innovation potential in Europe, has only been addressed in general terms. The commercial exploitation strategy of the results is not well elaborated. The benefits from training the ESRs is not clear for all partners Implementation Strengths: The project organisation and management structures are well outlined and their quality is very good for the overall feasibility of the project. The adequacy of the work plan and the activities proposed to reach the project objectives are well presented and are sound. Moreover, a list of high quality deliverables is provided. The institutional environment is very good. Good evidence of previous relevant experience, participant expertise and the supervisory record of senior researcher is given. The financial management strategy has been mentioned in sufficient detail and is adequate. Weaknesses: The progress monitoring mechanisms of the proposal are not sufficient. The nature of potential risks has not been addressed in detail. Project SOLIRING Excellence Strengths: The project is of high quality, innovative and credible. Novel technological concepts will be explored associated with very recent scientific discoveries in fundamental knowledge in an area of photonics, which is very promising for novel devices and functionalities. Strong multidisciplinary and interdisciplinary aspects of the research will be performed that span areas of applied mathematics, physics, advanced computation, metamaterials and nanophotonics. A good coupling to implementation in industry in the field of nonlinear optics is planned, with investigating different schemes of nanophotonic assemblies and carefully examining potential applications in the commercial sector and Aston University group contributing with specially equipped Labs. High quality of the knowledge sharing is planned between the Project members being at the top level of the international level within the domain of miniaturized frequency comb systems, some of them are pioneers of the field. Weaknesses: -None Impact Strengths: The proposal provides a very convincing Sec.3.2 on potential benefits to be derived from improved optics/photonics technology thus improving innovation potential at the European and global levels. Enhancing the research and innovation potential at the global (and European) level by secondments to and from the University pioneers in nano photonics. The project will enhance the ability of the ESRs through productive collaborations, and simultaneous ER and ESR secondments to one host organisation. At the end of the project, the participating ESRs will become competitive not only in academic environment, but also in industry. A good dissemination plan is envisaged via open access papers, talks, conferences. Added value is brought by the plan to disseminate the emerging results via presentations to industrial representatives of small and medium size companies. Consortium Workshops (4 in 36 months), regular meetings (>6 a year), and a web-portal of the project are convincingly described to provide a high clarity and quality knowledge sharing between the participants Weaknesses: There is an imbalance between ERs and ESRs in the proposal. Only general way towards protection of intellectual property rights is discussed, no particular strategy is proposed. Implementation Strengths: The essential work plan is well developed and clearly presented, including precise definitions of tasks, objectives and deliverables. The management structure is appropriate and contains several actions designed to maintain a high quality of research and exchange of knowledge. This is further enhanced by a very detailed allocation of task and resources, by carefully verifying all patentable results, and by assigning to each incoming seconded personnel a personal tutor in the host organization. The high level competence and large research experience of the participating organizations is presented. There is evidence that the participating institutions offer appropriate academic infrastructures for performing the planned research also for receiving several secondments at the same time. The institutional environment described in the proposal is optimal for this project. Expertise is shared in very complementary manner. Weaknesses: No specific action for gender equality aspects is given. The risk plan is focused on WP2, while other are neglected.