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CHAPTER 13 RNA & Protein Synthesis 13.1 The Role of RNA 13.2 Ribosomes & Protein Synthesis 13.3 Mutations 13.4 Gene Regulation & Expression 100 100 100 100 200 200 200 200 300 300 300 300 400 400 400 400 500 500 500 500 600 600 600 600 700 700 700 700 800 800 800 800 900 900 900 900 1000 1000 1000 1000 1100 1100 1100 1100 1200 1200 1200 1200 1. RNA CONTAINS THE SUGAR A ribose. B deoxyribose. C glucose. D lactose. A RIBOSE. 2. UNLIKE DNA, RNA CONTAINS A adenine. B uracil. C phosphate groups. D thymine. B URACIL. 3. WHICH OF THE FOLLOWING ARE FOUND IN BOTH DNA AND RNA? A ribose, phosphate groups, and adenine B deoxyribose, phosphate groups, and guanine C phosphate groups, guanine, and cytosine D phosphate groups, guanine, and thymine C PHOSPHATE GROUPS, GUANINE, AND CYTOSINE 4. WHICH NUCLEOTIDE IN FIGURE 13–1 INDICATES THE NUCLEIC ACID ABOVE IS RNA? A uracil B guanine C cytosine D adenine Figure 13–1 A URACIL 5. WHICH OF THE FOLLOWING IS TRUE? A RNA is usually single-stranded. B DNA is usually single-stranded. C DNA contains uracil. D RNA contains thymine. A RNA IS USUALLY SINGLE-STRANDED. 6. WHICH TYPE OF RNA BRINGS THE INFORMATION IN THE GENETIC CODE FROM THE NUCLEUS TO OTHER PARTS OF THE CELL? A rRNA B tRNA C mRNA D RNA polymerase C MRNA 7. HOW MANY MAIN TYPES OF RNA ARE THERE? A 1 B 3 C hundreds D thousands B 3 8. WHICH OF THE FOLLOWING STATEMENTS IS TRUE OF EUKARYOTIC DNA? A A promoter is part of an intron. B An intron is part of a promoter. C Introns are sequences of DNA. D Exons are edited out of pre-mRNA. C INTRONS ARE SEQUENCES OF DNA. 9. WHICH MOLECULES ARE INVOLVED IN PROTEIN SYNTHESIS? A transfer RNA, introns, and mutagens B messenger RNA, introns, and ribosomal RNA C ribosomal RNA, transfer RNA, and mutagens D messenger RNA, ribosomal RNA, and transfer RNA D MESSENGER RNA, RIBOSOMAL RNA, AND TRANSFER RNA 10. FROM WHICH MOLECULES ARE MRNA MOLECULES TRANSCRIBED? A tRNA B rRNA C DNA D proteins C DNA 11. WHAT IS PRODUCED DURING TRANSCRIPTION? A RNA molecules B DNA molecules C RNA polymerase D proteins A RNA MOLECULES 12. DURING EUKARYOTIC TRANSCRIPTION, AN RNA MOLECULE IS FORMED THAT IS A complementary to both strands of DNA. B identical to an entire single strand of DNA. C double-stranded and inside the nucleus. D complementary to part of one strand of DNA . D COMPLEMENTARY TO PART OF ONE STRAND OF DNA . 13. WHAT DOES FIGURE 13–2 SHOW? A anticodons B exons C introns D the genetic code Figure 13–2 D THE GENETIC CODE 14. HOW MANY NUCLEOTIDES ARE NEEDED TO SPECIFY THREE AMINO ACIDS? A 3 B 6 C 9 D 12 C 9 15. THERE ARE 64 CODONS AND 20 AMINO ACIDS. WHICH OF THE FOLLOWING IS TRUE? A Several different codons can specify the same amino acid. B Each codon specifies a different amino acid. C Some amino acids have no link to a codon. D Each amino acid is specified by only one codon. A SEVERAL DIFFERENT CODONS CAN SPECIFY THE SAME AMINO ACID. 16. IN FIGURE 13–3, WHICH AMINO ACID IS SPECIFIED BY THE MRNA CODE CCC? A Gly B Lys C Ala D Pro Figure 13–3 D PRO 17. ACCORDING TO FIGURE 13–3, WHICH CODE SPECIFIES THE SAME AMINO ACID AS UAU? A UAC B UAA C UGC D UGU Figure 13–3 A UAC 18. A PROMOTER IS A A binding site for DNA polymerase. B binding site for RNA polymerase. C start signal for replication. D stop signal for transcription. B BINDING SITE FOR RNA POLYMERASE. 19. WHAT HAPPENS DURING TRANSLATION? A Messenger RNA is made from a DNA code. B The cell uses a messenger RNA code to make proteins. C Transfer RNA is made from a messenger RNA code. D Copies of DNA molecules are made. B THE CELL USES A MESSENGER RNA CODE TO MAKE PROTEINS. 20. WHICH OF THE FOLLOWING TERMS IS LEAST CLOSELY RELATED TO THE OTHERS? A spindle fiber B tRNA C polypeptide D anticodon A SPINDLE FIBER 21. DURING TRANSLATION, THE TYPE OF AMINO ACID THAT IS ADDED TO THE GROWING POLYPEPTIDE DEPENDS ON THE A codon on the mRNA and the anticodon on the rRNA. B anticodon on the mRNA and the anticodon on the tRNA. C anticodon on the rRNA and the codon on the mRNA. D codon on the mRNA and the anticodon on the tRNA. D CODON ON THE MRNA AND THE ANTICODON ON THE TRNA. 22. A PROTEIN IS BEING ASSEMBLED WHEN A DNA is being translated. B RNA is being transcribed. C RNA is being translated. D DNA is being transcribed. C RNA IS BEING TRANSLATED. 23. GENES CONTAIN INSTRUCTIONS FOR ASSEMBLING A operons. B nucleosomes. C proteins. D mutagens. C PROTEINS. 24. WHICH IS THE CORRECT SEQUENCE OF THE TRANSFER OF INFORMATION IN MOST ORGANISMS? A protein to DNA to RNA B RNA to DNA to protein C DNA to RNA to protein D RNA to protein to DNA C DNA TO RNA TO PROTEIN 25. WHAT IS AN EXCEPTION TO THE CENTRAL DOGMA OF MOLECULAR BIOLOGY? A Viruses sometimes transfer information from RNA to DNA. B Viruses sometimes transfer information from DNA to RNA. C Viruses sometimes transfer information from proteins to DNA. D Viruses can translate without RNA. A VIRUSES SOMETIMES TRANSFER INFORMATION FROM RNA TO DNA. 26. THE GENETIC CODE IS ALWAYS READ A 3 bases at a time in the same direction. B 4 bases at a time in the same direction. C 3 bases at a time and the direction varies. D 4 bases at a time and the direction varies. A 3 BASES AT A TIME IN THE SAME DIRECTION. 27. IN EUKARYOTES A Transcription takes place in the cytoplasm, and translation takes place in the nucleus. B Transcription takes place in the nucleus, and translation takes place in the cytoplasm. C Transcription and translation both take place in the nucleus. D Transcription and translation both take place in the cytoplasm. B TRANSCRIPTION TAKES PLACE IN THE NUCLEUS, AND TRANSLATION TAKES PLACE IN THE CYTOPLASM. 28. A MUTATION THAT INVOLVES ONE OR A FEW NUCLEOTIDES IS CALLED A a mutagen. B an inversion. C a point mutation. D a translocation. C A POINT MUTATION. 29. WHICH OF THE FOLLOWING IS A CHROMOSOMAL MUTATION? A inversion B insertion C point mutation D substitution A INVERSION 30. WHICH OF THE FOLLOWING IS THE NAME OF A TYPE OF CHROMOSOMAL MUTATION AND A TYPE OF GENE MUTATION? A substitution B insertion C deletion D inversion C DELETION 31. WHEN A CHROMOSOME UNDERGOES A DELETION MUTATION, INFORMATION IS A repeated. B lost. C reversed. D transferred. B LOST. 32. MOST MUTATIONS A have no effect on an organism. B are fatal to an organism. C are helpful to an organism. D are harmful to an organism. A HAVE NO EFFECT ON AN ORGANISM. 33. WHAT ARE SOME CHARACTERISTICS OF POLYPLOIDY PLANTS? A They tend to be weaker and smaller than diploid plants. B They tend to be bigger and stronger than diploid plants. C They tend to be weaker, but bigger than diploid plants. D They tend to be smaller, but stronger than diploid plants. B THEY TEND TO BE BIGGER AND STRONGER THAN DIPLOID PLANTS. 34. WHICH OF THE FOLLOWING STATEMENTS IS TRUE ABOUT GENE REGULATION IN PROKARYOTES? A Promoters determine whether a gene is expressed. B Expressed genes make more DNA. C DNA-binding proteins determine whether a gene is expressed. D RNA polymerase regulates gene expression. C DNA-BINDING PROTEINS DETERMINE WHETHER A GENE IS EXPRESSED. 35. IN E. COLI, THE LAC OPERON CONTROLS THE A breakdown of lactose. B production of lactose. C breakdown of glucose. D production of glucose. A BREAKDOWN OF LACTOSE. 36. A LAC REPRESSOR TURNS OFF THE LAC GENES BY A binding to the promoter. B DNA polymerase. C binding to the operator. D binding to the lac genes. C BINDING TO THE OPERATOR. 37. WHEN E. COLI IS GROWN ON GLUCOSE, AND THERE IS NO LACTOSE AVAILABLE A lactose molecules bind to the lac repressor. B the lac repressor binds to the operator of the lac operon. C RNA polymerase binds to the promoter of the lac operon. D the lac genes are transcribed into messenger RNA. B THE LAC REPRESSOR BINDS TO THE OPERATOR OF THE LAC OPERON. 38. WHICH IS INVOLVED WITH THE REGULATION OF EUKARYOTIC GENES? A operon B DNA polymerase C TATA box D operator C TATA BOX 39. WHICH OF THE FOLLOWING IS PART OF ONLY PROKARYOTIC GENES? A operon B TATA box C promoter sequences D enhancer sequences A OPERON 40. GENE REGULATION IN EUKARYOTES A usually involves operons. B is simpler than in prokaryotes. C allows for cell specialization. D includes the action of an operator region. C ALLOWS FOR CELL SPECIALIZATION. 41. SPECIALIZED CELLS REGULATE THE EXPRESSION OF GENES BECAUSE THEY A do not want the genes to become worn out. B cannot control the translation of proteins. C do not carry the complete genetic code in their nuclei. D do not need the proteins that are specified by certain genes. D DO NOT NEED THE PROTEINS THAT ARE SPECIFIED BY CERTAIN GENES. 42. WHAT REGULATES THE EXPRESSION OF MOST EUKARYOTIC GENES? A miRNA B transcription factors C dicer enzymes D silencing complexes B TRANSCRIPTION FACTORS 43. HOX GENES DETERMINE AN ANIMAL’S A body plan. B size. C skin color. D eye color. A BODY PLAN. 44. HOX GENES A determine when bacteria replicate their chromosome. B determine where the flagellum is on a bacterium. C determine when a dog’s cells replicate their DNA D determine the location of a dog’s ears. D DETERMINE THE LOCATION OF A DOG’S EARS. 45. THE BASIC BODY STRUCTURE OF THE FLY IN FIGURE 13–4 IS DETERMINED BY A CLUSTER OF A repressor genes. B Hox genes. C polypeptides. D frameshift mutations. Figure 13–4 B HOX GENES.