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http://www.medicine-on-line.com Case 038: Faint and distant heart sounds. Authors: David C Chung MD, FRCPC Faint & distant heart sounds: 1/4 Thomas YK Chan MD, PhD, FRCP Affiliation: The Chinese University of Hong Kong A 56 year-old woman was admitted to hospital for right femoral hernia repair. She has always been in good health ever since childhood and could not remember when she was in a doctor’s office last. She was not taking any medications, did not smoke and did not drink alcoholic beverages, and had no history of allergy. She weighed 55 kg and was 165 cm tall. Her vital signs were: blood pressure 128/78 mmHg, pulse rate 64/min and regular, respiratory rate 12/min. Physical examination revealed that the heart sounds were faint and distant at the traditional apex area of the heart (5th intercostal space just medial to the left mid-clavicular line) but were clearly heard at the base. Auscultation of the lungs revealed normal breath sounds and, in addition, heart sounds that were clearly audible on the right side of her chest. Her preoperative ECG appears below: http://www.medicine-on-line.com Faint & distant heart sounds: 2/4 1. What are the abnormalities seen on this ECG? The obvious abnormalities are: Limb leads The P wave is negative in lead I and lead II, iso-electric in lead aVF, and positive in lead III—indicating an abnormal P wave axis in the direction of the foot and to the right. The QRS complex is negative in lead I but positive in lead aVF, indicating right axis deviation. Chest leads The tall R wave in V1 decreases progressively towards V6 instead of the normal progression of increasing R wave amplitude towards V6. Progress of the Case: An astute intern suspected the patient has dextrocardia and proved his case by repeating the ECG with the electrodes of the right and left arm reversed and the chest electrodes positioned in mirror-image positions on the right chest as shown below. http://www.medicine-on-line.com Faint & distant heart sounds: 3/4 The ECG he obtained appears below. It shows normal P wave and QRS axes as well as normal progression of R waves across the chest leads: NB: A more common condition leading to abnormalities seen in the limbs leads of the original ECG is reversal of the arm electrodes. If that is the case, the chest leads would be unaffected and should show normal R wave progression. 2. What is dextrocardia? Dextrocardia is a positional abnormality of the heart. Around the 4th week of gestation, the primordial heart tube normally bends to the right, placing the fully developed heart in the left chest with the cardiac apex pointing in the leftward direction. In dextrocardia, the primordial heart tube bends to the left, placing the fully developed heart in the right chest with the apex pointing in the rightward direction. With matching developments in the great vessels, the right-sided heart becomes a mirror image of the normal left-sided heart. The incidence is estimated to be 1 in 10,000 live births. Many of these patients have similar transposition of organs in the abdomen with a left-sided liver and right-sided stomach, a condition called situs inversus. Subjects with dextrocardia and situs inversus have low incidents of accompanying cardiac defects and function http://www.medicine-on-line.com Faint & distant heart sounds: 4/4 normally throughout life, their condition being discovered only by accident when they have an ECG, chest x-ray, and at surgery or autopsy. On the other hand, subjects who have isolated dextrocardia without situs inversus are prone to have serious cardiac anomalies. Progress of the Case: Chest x-ray confirmed that the patient had dextrocardia. There was no cardiac defects seen on echocardiography, and abdominal ultrasound confirmed situs inversus. Further reading Marelli AJ. Chapter 65 – Congenital heart disease in adults. In Goldman: Cecil Textbook of Medicine, 22nd edition. Saunders, 2004.