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Principles Of Oncology 1.In a 23 years old female with an asymptomatic 2-cm mass in the lower pole of the right thyroid lobe,the most appropriate diagnostic approach is: A.Excisional biopsy. B.Incisional biopsy. C.Tru-cut biopsy. D.Fine needle aspiration cytology (FNAC). Answer : D 2. a 53 years old male patient who has been diagnosed to have colon cancer, the appropriate oncologic resection is: A.Resection of the mass only. B.Trans- anal excision with negative margin. C.Resection of the mass with adequate negative proximal and distal margins as well as adequate lymph node sampling. D.Ileocolic bypass of the mass. Answer: C 3.The aim of Frozen Section (F.S) is: A.To assess the resected specimen margins. B.To know the final and definitive diagnosis. C.To know the preliminary diagnosis. D. A and C. Answer: D. 4.A 46 years old lady who presented with a big mass in the right thigh of two months duration, the ideal orientation of the biopsy incision would be : A. B. C. D. Transverse incision. .Longitudinal Incision. Oblique incision. Circumferential incision. Answer : B 5. A 48 years old lady who was diagnosed to have left breast cancer, she was investigated then underwent surgical excision( Lumpectomy and axillary dissection), the first important step to do after excision of the lump is; A. To Mark the excised specimen margins. B. To immediately stain the specimen. C. To send the specimen for Frozen Section. D. To keep it in normal saline. Answer : A Breast Cancer 1.All of the following are invasive breast cancer EXCEPT: A.Invasive ductal carcinoma (NOS). B.Tubular carcinoma. C.Ductal carcinoma in situ. D.Medulary breast carcinoma. Answer is: C 2.The surgical management for ductal carcinoma in situ is: A.Modefied radical mastectomy. B.Lumpectomy or simple mastectomy without axillary lymph node dissection. C.Chemotherapy alone. D.Combined chemoradiation therapy. Answer is: B 3.Stage III breast cancer is clinically characterized by: A. A single mobile axillary lymph node. B. A 2 cm breast mass with clinically and pathologically negative axillary lymph nodes. C. A 5 cm breast mass with a single non-enhancing liver lesion. D. A small breast mass with fixed matted axillary lymph nodes. Answer is: D 4. A 47 years old lady who presented to the clinic with a history of painless left breast mass,nipple retraction and discharge since two months ,her examination showed around 2x2 cm breast mass with nipple retraction and no palpable axillary lymph nodes.The best diagnostic procedure would be: A.Fine needle aspiration cytology (FNAC). B.Ultrasound of the breast. C.Mammogram. D.True-cut biopsy Answer is: D. 5.The commonest sites for breast cancer metastasis are all of the following EXCEPT: A.Liver. B.Lungs. C.Adrenal glands. D.Bone. Answer is: C Esophageal and Gastric Tumors 1. All of The following gastric polyps are benign EXCEPT: A. Hyperplasic polyps. B. Villous polyps. C. Inflammatory polyps. D. Gastric fundic polyps. Answer is: B 2.All of the following are considered risk factors for esophageal cancer EXCEPT: A. Alcohol. B. Smoking. C.Achalasia. D.Barrett esophagus. Answer : D 3. 50% of cases of Squamous cell carcinoma (SCC) of the esophagus involve: A. The Upper third. B. The middle third. C. Th lower third. D. The cervical portion of the esophagus. Answer : B 4.The best surgical management for proximal gastric cancer is: A.Total gastrectomy. B.Distal gastrectomy. C.Proximal subtotal gastrectomy. D.Gastrojejnostomy. Answer is: A 5. All of the following benign conditions are associated with increased rates of gastric carcinoma except: A. B. C. D. Pernicious anemia. Multiple endocrine neoplasia type I (MEN 1). Adenomatous polyps. Chronic atrophic gastritis. Answer is: B 6. Blood supply of the stomach is mainly from: A.Superior mesenteric artery (SMA). B.Inferior mesenteric artery (IMA). C.Celiac Trunk. D.Non of the above. Answer : C Hepatobiliary Tumors 1.All of the following are metastatic liver tumors EXCEPT: A.Cholangiocarcinoma. B.Melanoma. C.Renal cell carcinoma. D.Sarcoma. Answer: A 2.All of the following are benign liver diseases EXCEPT: A.Focal Nodular Hyperplasia (FNH). B.Hepatic Adenoma. C.Hepatoma. D.Hemangioma. Answer : C 3.Correct statement about hepatic adenoma : A.Adenomas are best diagnosed by percutaneous biopsy. B.Lesions are frequently associated with oral contraceptive use. C. Adenomas are considered as high risk for malignant transformation. D.All adenomas should be resected. Answer : B 4.The following are risk factors that have been implicated in the development of Hepatocellular carcinoma (HCC) EXCEPT: A.Hepatitis C. B.Hepatitis B. C.Alcohol. D.Heptic Hemangioma. Answer: D 5.Tru statement about Focal Nodular Hyperplasia (FNH) is: A.The development of the lesion is mainly related to the use of oral contraceptive pills. B.Spontaneous intraperitoneal hemorrhage is a common complication. C.Most lesions are asymptomatic. D.The frequency of malignant degeneration is an indication for resection. Answer : C